Publications by authors named "Alexandre Mutchmore"

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[In patients with ischemic stroke, with symptom onset between 4.5 and 24hours, and salvageable brain parenchyma assessed by perfusion CT, without a plan for thrombectomy, does alteplase improve functional independence at 90 days, compared with standard therapy, while being safe?].
Luc Lanthier, Emmanuelle Lapointe, Alexandre Mutchmore, Marc-Émile Plourde, Michel Cauchon

Rev Med Interne· November 2025

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[In patients with metabolic dysfunction-associated steatohepatitis and moderate to advanced liver fibrosis, does semaglutide (2.4mg subcutaneously every week) improve liver histology compared to placebo, and is it safe?].
Alexandre Mutchmore, Dusanka Grbic, Michel Cauchon, Marc-Émile Plourde, Luc Lanthier

Rev Med Interne· October 2025

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[In patients with active cancer and venous thromboembolism who have been anticoagulated for at least 6 months, is extended treatment with a reduced dose of apixaban effective in preventing recurrences and reducing the risk of bleeding, compared to a full dose?].
Luc Lanthier, Geneviève Le Templier, Alexandre Mutchmore, Marc-Émile Plourde, Michel Cauchon

Rev Med Interne· September 2025

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[In patients with type 2 diabetes at high risk of cardiovascular events, does oral semaglutide decrease the risk of major adverse cardiovascular events compared to placebo, and is it safe?].
Alexandre Mutchmore, Mathieu Labossière, Michel Cauchon, Marc-Émile Plourde, Luc Lanthier

Rev Med Interne· July 2025

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[In patients with asymptomatic severe aortic stenosis, does a transcatheter aortic-valve replacement improve prognosis, and is it safe?].
Luc Lanthier, Alexandre Mutchmore, Marc-Émile Plourde, Michel Cauchon

Rev Med Interne· June 2025

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[In hospitalized patients with bacteremia, is a 7-day antibiotic treatment noninferior to a 14-day treatment with respect to mortality?].
Luc Lanthier, Alex Carignan, Alexandre Mutchmore, Marc-Émile Plourde, Michel Cauchon

Rev Med Interne· March 2025

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[In patients with obesity and moderate to severe obstructive sleep apnea, is tirzepatide effective in reducing the apnea-hypopnea index compared to placebo, and is it safe?].
Alexandre Mutchmore, Michel Cauchon, Marc-Émile Plourde, Luc Lanthier

Rev Med Interne· February 2025

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[In patients with heart failure with preserved or mildly reduced ejection fraction, is finerenone effective in reducing a composite of heart failure exacerbation and cardiovascular death compared to placebo, and is it safe?].
Luc Lanthier, Alexandre Mutchmore, Marc-Émile Plourde, Michel Cauchon

Rev Med Interne· January 2025

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[In mechanically ventilated adult patients admitted to intensive care, does the use of pantoprazole for prophylaxis reduce the risk of gastrointestinal bleeding compared to placebo, and is it safe?].
Luc Lanthier, Michaël Mayette, Alexandre Mutchmore, Marc-Émile Plourde, Michel Cauchon

Rev Med Interne· December 2024

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[Among patients with type 2 diabetes and chronic kidney disease, does semaglutide prevent end-stage renal disease, significant loss of kidney function, or death from renal or cardiovascular causes compared to placebo, and is it safe?].
Luc Lanthier, Alexandre Mutchmore, Marc-Émile Plourde, Michel Cauchon

Rev Med Interne· October 2024

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Automated APACHE II and SOFA score calculation using real-world electronic medical record data in a single center.
Alexandre Mutchmore, François Lamontagne, Michaël Chassé, Lynne Moore, Michael Mayette

J Clin Monit Comput· August 2023

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