Publications by authors named "Alexei V Tulin"

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PARP1 and PARG Are the Draft Horses for Polycomb-Trithorax Chromatin Regulator Machinery.
Guillaume Bordet, Alexei V Tulin

Biomolecules· September 2025

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Disordered Protein Tail Is Wagging Poly(ADP-ribosyl)ation.
Guillaume Bordet, Yaroslava Karpova, Saraynia Espeseth, Gavin Mitzel, Zachary Bigelow, Alexei V Tulin

Int J Mol Sci· August 2025

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PARG Mutation Uncovers Critical Structural Determinant for Poly(ADP-Ribose) Hydrolysis and Chromatin Regulation in Embryonic Stem Cells.
Yaroslava Karpova, Sara Piatz, Guillaume Bordet, Alexei V Tulin

Cells· July 2025

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Adaptive genetic mechanisms in mammalian Parp1 locus.
Yaroslava Karpova, Alexei V Tulin

G3 (Bethesda)· September 2024

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PARG Protein Regulation Roles in Longevity Control.
Guillaume Bordet, Alexei V Tulin

Int J Mol Sci· June 2024

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Disrupting Poly(ADP-ribosyl)ating Pathway Creates Premalignant Conditions in Mammalian Liver.
Yaroslava Karpova, David J Orlicky, Edward E Schmidt, Alexei V Tulin

Int J Mol Sci· December 2023

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Poly(ADP-ribosyl)ating enzymes coordinate changes in the expression of metabolic genes with developmental progression.
Guillaume Bordet, Gbolahan Bamgbose, Alexei V Tulin

Sci Rep· November 2023

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The Drosophila gene encoding JIG protein (CG14850) is critical for CrebA nuclear trafficking during development.
Sayem H Bhuiyan, Guillaume Bordet, Gbolahan Bamgbose, Alexei V Tulin

Nucleic Acids Res· June 2023

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Chromatin Immunoprecipitation Approach to Determine How PARP1 Domains Affect Binding Pattern to Chromatin.
Guillaume Bordet, Gbolahan Bamgbose, Sayem H Bhuiyam, Sarah Johnson, Alexei V Tulin

Methods Mol Biol· December 2022

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Using Drosophila Genetics to Identify Factors that Affect PARP1 Activity In Vivo.
Guillaume Bordet, Alexei V Tulin

Methods Mol Biol· December 2022

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Generating PARP Knockout D. melanogaster with CRISPR/Cas9 System.
Yaroslava Karpova, Alexei V Tulin

Methods Mol Biol· December 2022

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TaqMan Multiplex qPCR Method to Genotype PARG Knockout Mice.
Yaroslava Karpova, Alexei V Tulin

Methods Mol Biol· December 2022

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Cell-Based Screening for New PARP Inhibitors Utilizing PARG-Mutated Mouse Embryonic Stem Cells.
Yaroslava Karpova, Danping Guo, Alexei V Tulin

Methods Mol Biol· December 2022

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Poly(ADP-ribosyl)ating enzymes cooperate to coordinate development.
Guillaume Bordet, Iaroslava Karpova, Alexei V Tulin

Sci Rep· December 2022

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Upregulation of PARG in prostate cancer cells suppresses their malignant behavior and downregulates tumor-promoting genes.
Yaroslava Karpova, Sarah J Johnson, Guillaume Bordet, Danping Guo, Atreyi Ghatak, Alexei V Tulin

Biomed Pharmacother· September 2022

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PARG suppresses tumorigenesis and downregulates genes controlling angiogenesis, inflammatory response, and immune cell recruitment.
Sarah Johnson, Yaroslava Karpova, Danping Guo, Atreyi Ghatak, Dmitriy A Markov, Alexei V Tulin

BMC Cancer· May 2022

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Poly(ADP-ribosyl)ating pathway regulates development from stem cell niche to longevity control.
Guillaume Bordet, Elena Kotova, Alexei V Tulin

Life Sci Alliance· March 2022

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Poly(ADP)-Ribosylation Inhibition: A Promising Approach for Clear Cell Renal Cell Carcinoma Therapy.
Yaroslava Karpova, Danping Guo, Peter Makhov, Adam M Haines, Dmitriy A Markov, Alexei V Tulin

Cancers (Basel)· October 2021

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Histone-dependent PARP-1 inhibitors: A novel therapeutic modality for the treatment of prostate and renal cancers.
Peter Makhov, Robert G Uzzo, Alexei V Tulin, Vladimir M Kolenko

Urol Oncol· June 2021

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Poly(ADP-ribose) polymerase 1 in genome-wide expression control in Drosophila.
Guillaume Bordet, Niraj Lodhi, Danping Guo, Andrew Kossenkov, Alexei V Tulin

Sci Rep· December 2020

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Non-NAD-like PARP-1 inhibitors in prostate cancer treatment.
Yaroslava Karpova, Chao Wu, Ali Divan, Mark E McDonnell, Elizabeth Hewlett, Alexei V Tulin

Biochem Pharmacol· September 2019

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Hit and run versus long-term activation of PARP-1 by its different domains fine-tunes nuclear processes.
Colin Thomas, Yingbiao Ji, Chao Wu, Haily Datz, Cody Boyle, Alexei V Tulin

Proc Natl Acad Sci U S A· May 2019

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Non-NAD-like PARP1 inhibitor enhanced synthetic lethal effect of NAD-like PARP inhibitors against BRCA1-deficient leukemia.
Margaret Nieborowska-Skorska, Silvia Maifrede, Min Ye, Monika Toma, Elizabeth Hewlett, Alexei V Tulin

Leuk Lymphoma· April 2019

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PARP-1 Interaction with and Activation by Histones and Nucleosomes.
Colin Thomas, Elena Kotova, Alexei V Tulin

Methods Mol Biol· April 2018

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High-Throughput Colorimetric Assay for Identifying PARP-1 Inhibitors Using a Large Small-Molecule Collection.
Elena Kotova, Alexei V Tulin

Methods Mol Biol· April 2018

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