Publications by authors named "Alexey Proshin"

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Combining Experimental and Computational Methods to Produce Conjugates of Anticholinesterase and Antioxidant Pharmacophores with Linker Chemistries Affecting Biological Activities Related to Treatment of Alzheimer's Disease.
Galina F Makhaeva, Nadezhda V Kovaleva, Elena V Rudakova, Natalia P Boltneva, Sofya V Lushchekina, Alexey N Proshin

Molecules· January 2024

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Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: -Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile.
Galina F Makhaeva, Nadezhda V Kovaleva, Natalia P Boltneva, Elena V Rudakova, Sofya V Lushchekina, Alexey N Proshin

Molecules· February 2022

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Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment.
Galina F Makhaeva, Sofya V Lushchekina, Nadezhda V Kovaleva, Tatiana Yu Astakhova, Natalia P Boltneva, Alexey N Proshin

Bioorg Chem· July 2021

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New Multifunctional Agents Based on Conjugates of 4-Amino-2,3-polymethylenequinoline and Butylated Hydroxytoluene for Alzheimer's Disease Treatment.
Galina F Makhaeva, Nadezhda V Kovaleva, Elena V Rudakova, Natalia P Boltneva, Sofya V Lushchekina, Alexey N Proshin

Molecules· December 2020

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New Hybrids of 4-Amino-2,3-polymethylene-quinoline and -Tolylsulfonamide as Dual Inhibitors of Acetyl- and Butyrylcholinesterase and Potential Multifunctional Agents for Alzheimer's Disease Treatment.
Galina F Makhaeva, Nadezhda V Kovaleva, Natalia P Boltneva, Sofya V Lushchekina, Tatiana Yu Astakhova, Alexey N Proshin

Molecules· August 2020

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Corrigendum to "Conjugates of tacrine and 1,2,4-thiadiazole derivatives as new potential multifunctional agents for Alzheimer's disease treatment: Synthesis, quantum-chemical characterization, molecular docking, and biological evaluation". [Bioorg. Chem. 94C (2019)].
Galina F Makhaeva, Nadezhda V Kovaleva, Natalia P Boltneva, Sofya V Lushchekina, Elena V Rudakova, Alexey N Proshin

Bioorg Chem· March 2020

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Conjugates of tacrine and 1,2,4-thiadiazole derivatives as new potential multifunctional agents for Alzheimer's disease treatment: Synthesis, quantum-chemical characterization, molecular docking, and biological evaluation.
Galina F Makhaeva, Nadezhda V Kovaleva, Natalia P Boltneva, Sofya V Lushchekina, Elena V Rudakova, Alexey N Proshin

Bioorg Chem· January 2020

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Cocrystals of a 1,2,4-thiadiazole-based potent neuroprotector with gallic acid: solubility, thermodynamic stability relationships and formation pathways.
Artem O Surov, Andrei V Churakov, Alexey N Proshin, Xia-Lin Dai, Tongbu Lu

Phys Chem Chem Phys· May 2018

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Effects of Biorelevant Media Components on Dissolution Behaviour of 1,2,4-Thiadiazole Derivative Designed for Alzheimer's Disease Prevention.
Maria Promzeleva, Mikhail Chislov, Tatyana Volkova, Alexey Proshin, Roman Kumeev

Chem Biodivers· February 2018

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Improved Biopharmaceutical Properties of Oral Formulations of 1,2,4-Thiadiazole Derivative with Cyclodextrins: in Vitro and in Vivo Evaluation.
Maria Promzeleva, Tatyana Volkova, Alexey Proshin, Oleg Siluykov, Anton Mazur

ACS Biomater Sci Eng· February 2018

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Cocrystal formation, crystal structure, solubility and permeability studies for novel 1,2,4-thiadiazole derivative as a potent neuroprotector.
Artem O Surov, Tatyana V Volkova, Andrei V Churakov, Alexey N Proshin, Irina V Terekhova

Eur J Pharm Sci· November 2017

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Synthesis, molecular docking and biological evaluation of N,N-disubstituted 2-aminothiazolines as a new class of butyrylcholinesterase and carboxylesterase inhibitors.
Galina F Makhaeva, Natalia P Boltneva, Sofya V Lushchekina, Olga G Serebryakova, Tatyana S Stupina, Alexey N Proshin

Bioorg Med Chem· March 2016

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Synthesis, biological activity, distribution and membrane permeability of novel spiro-thiazines as potent neuroprotectors.
Svetlana V Blokhina, Tatyana V Volkova, Marina V Ol'khovich, Angelica V Sharapova, Alexey N Proshin

Eur J Med Chem· April 2014

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Concomitant manipulation of murine NMDA- and AMPA-receptors to produce pro-cognitive drug effects in mice.
Julie Vignisse, Harry W M Steinbusch, Vladimir Grigoriev, Alexei Bolkunov, Alexey Proshin

Eur Neuropsychopharmacol· February 2014

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Crystal structure analysis and sublimation thermodynamics of bicyclo derivatives of a neuroprotector family.
Artem O Surov, Alexey N Proshin, German L Perlovich

Acta Crystallogr B Struct Sci Cryst Eng Mater· February 2014

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Novel 1,2,4-thiadiazole derivatives: crystal structure, conformational analysis, hydrogen bond networks, calculations, and thermodynamic characteristics of crystal lattices.
Artem O Surov, Cong Trinh Bui, Alexey N Proshin, Pascal Roussel, Abdenacer Idrissi

J Phys Chem B· September 2013

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Novel 1,2,4-thiadiazole derivatives as potent neuroprotectors: approach to creation of bioavailable drugs.
German L Perlovich, Alexey N Proshin, Tatyana V Volkova, Ludmila N Petrova, Sergey O Bachurin

Mol Pharm· August 2012

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Thermodynamic and structural aspects of novel 1,2,4-thiadiazoles in solid and biological mediums.
German L Perlovich, Alexey N Proshin, Tatyana V Volkova, Cong Trinh Bui, Sergey O Bachurin

Mol Pharm· October 2011

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Synthesis, pharmacology, crystal properties, and quantitative solvation studies from a drug transport perspective for three new 1,2,4-thiadiazoles.
German L Perlovich, Tatyana V Volkova, Alexey N Proshin, Dmitriy Yu Sergeev, Cong Trinh Bui

J Pharm Sci· September 2010

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Novel isothiourea derivatives as potent neuroprotectors and cognition enhancers: synthesis, biological and physicochemical properties.
German L Perlovich, Alexey N Proshin, Tatyana V Volkova, Sergey V Kurkov, Vlaimir V Grigoriev

J Med Chem· April 2009

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