Publications by authors named "Alexis Combes"

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The coming era of nudge drugs for cancer.
Tristan Courau, Arpita Desai, Allon Wagner, Alexis J Combes, Matthew F Krummel

Cancer Cell· November 2025

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TriLeukeVax: A CD80/IL-15/IL-15Rα Expressing Autologous AML Cell Vaccine Elicits Robust Anti-Leukemic Cytolytic Activity.
Jacob Du, Uthpala N Wijayaratna, Xinyue Wang, Jeffrey P Fung, Belinda Huang, Alexis J Combes

bioRxiv· November 2025

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Spatial Transcriptomics Reveals Fibroblasts as Central Immune Organizers through CXCR4 Signaling in Abdominal Aortic Aneurysm.
Dina Levy-Lambert, Joel L Ramirez, Saba Shaikh, Cesar De Jeronimo Diaz, April G Huang, Alexis Combes

bioRxiv· November 2025

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Single-cell proteomics characterization of bone marrow hematopoiesis with distinct Ras pathway lesions.
Laila Karra, Anna-Marie Finger, Lauren Shechtman, Milana Krush, Rita Meng-Yao Huang, Alexis J Combes

Blood Adv· October 2025

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Clinical cure of chronic hepatitis B is dependent on activation and perpetuation of robust CD4 T cell responses.
Jillian M Jespersen J, Lia Avanesyan, Jean Publicover, Nicholas D Carey, Ravi K Patel, Alexis J Combes

bioRxiv· October 2025

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STING activation reshapes the tumor microenvironment leading to tumor regression in osteosarcoma.
Elizabeth P Young, Christine A Johnson, Alex G Lee, Douglass Morris, Jessica Tsui, Alexis J Combes

bioRxiv· October 2025

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Persistent and progressive acute lung allograft dysfunction is linked to cell compositional and transcriptional changes in small airways.
Elsa Brunet-Ratnasingham, Shivaram Yellamilli, Ruyin Guo, Rashmi Prava Mohanty, Allen Duong, Alexis J Combes

J Heart Lung Transplant· September 2025

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Discovery of a Linked Constellation of Gene Expression Revealed by Local Editing of Fibroblasts in Tumors.
Nicholas F Kuhn, Itzia Zaleta-Linares, Kenneth H Hu, Tristan Courau, Brittany Davidson, Alexis J Combes

bioRxiv· August 2025

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Single-Cell Profiling Reveals Altered Endometrial Cellular Features Across the Menstrual Cycle in Endometriosis Patients.
Ana Almonte-Loya, Wanxin Wang, Sahar Houshdaran, Xinyu Tang, Emily Flynn, Alexis Combes

bioRxiv· August 2025

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Anticlustering for sample allocation to minimize batch effects.
Martin Papenberg, Cheng Wang, Maïgane Diop, Syed Hassan Bukhari, Boris Oskotsky, Alexis J Combes

Cell Rep Methods· August 2025

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Multimodal delineation of a layer of effector function among exhausted CD8 T cells in tumors.
Arja Ray, Molly Bassette, Kenneth H Hu, Lomax F Pass, Tristan Courau, Alexis J Combes

Sci Immunol· July 2025

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Tumor cell heterogeneity drives spatial organization of the intratumoral immune response.
Miho Tanaka, Lotus Lum, Kenneth H Hu, Piyush Chaudhary, Savannah Hughes, Alexis J Combes

J Exp Med· June 2025

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CD38 expression by neonatal human naïve CD4 T cells shapes their distinct metabolic state and tolerogenic potential.
Laura R Dwyer, Andrea M DeRogatis, Sean Clancy, Victoire Gouirand, Charles Chien, Alexis J Combes

bioRxiv· June 2025

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Transient Dietary Changes Modulate Inflammatory Disease Trajectory in the Lean State.
Zewen Jiang, John M Tayeri, Chihiro Tabuchi, Sarah G Gayer, Arum Yoo, Alexis J Combes

bioRxiv· June 2025

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Decoding functional hematopoietic progenitor cells in the adult human lung.
Catharina Conrad, Mélia Magnen, Jessica Tsui, Harrison Wismer, Mohammad Naser, Alexis J Combes

Blood· May 2025

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Single-cell omics technologies - Fundamentals on how to create single-cell looking glasses for reproductive health.
Maïgane Diop, Brittany R Davidson, Gabriela K Fragiadakis, Marina Sirota, Brice Gaudillière, Alexis J Combes

Am J Obstet Gynecol· April 2025

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KDM6B-dependent epigenetic programming of uterine fibroblasts in early pregnancy regulates parturition timing in mice.
Tara I McIntyre, Omar Valdez, Nathan P Kochhar, Brittany Davidson, Bushra Samad, Alexis J Combes

Cell· March 2025

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Identification of a conserved subset of cold tumors responsive to immune checkpoint blockade.
Jade Moore, Jim Gkantalis, Ines Guix, William Chou, Kobe Yuen, Alexis Combes

J Immunother Cancer· March 2025

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A positive ReceptivaDx result for BCL6 does not correlate with abnormal ERA results or decreased expression of receptivity-associated markers: two sides of the endometrial receptivity coin in fertility evaluation and treatment.
David Huang, Emily Flynn, Ana Almonte-Loya, Brittany Davidson, Meagan Chan, Alexis J Combes

F S Sci· February 2025

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Targeting CD206+ macrophages disrupts the establishment of a key antitumor immune axis.
Arja Ray, Kenneth H Hu, Kelly Kersten, Tristan Courau, Nicholas F Kuhn, Alexis J Combes

J Exp Med· January 2025

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Coordinated variation in the immune systems and microbiomes of healthy humans is linked to tonic interferon states.
Joel Babdor, Ravi K Patel, Brittany Davidson, Cecilia Noecker, Maha Rahim, Alexis J Combes

bioRxiv· December 2024

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Proinflammatory immune cells disrupt angiogenesis and promote germinal matrix hemorrhage in prenatal human brain.
Jiapei Chen, Elizabeth E Crouch, Miriam E Zawadzki, Kyle A Jacobs, Lakyn N Mayo, Alexis J Combes

Nat Neurosci· November 2024

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Chromatin remodelling drives immune cell-fibroblast communication in heart failure.
Michael Alexanian, Arun Padmanabhan, Tomohiro Nishino, Joshua G Travers, Lin Ye, Alexis J Combes

Nature· November 2024

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Single-cell spatial transcriptomics of fixed, paraffin-embedded biopsies reveals colitis-associated cell networks.
Elvira Mennillo, Madison L Lotstein, Gyehyun Lee, Vrinda Johri, Christina Ekstrand, Alexis J Combes

bioRxiv· November 2024

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Tumor-associated macrophages restrict CD8 T cell function through collagen deposition and metabolic reprogramming of the breast cancer microenvironment.
Kevin M Tharp, Kelly Kersten, Ori Maller, Greg A Timblin, Connor Stashko, Alexis J Combes

Nat Cancer· July 2024

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