Publications by authors named "Alfred Sun"

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BrainSTEM: A single-cell multiresolution fetal brain atlas reveals transcriptomic fidelity of human midbrain cultures.
Hilary S Y Toh, Lisheng Xu, Carissa Chen, Pengyi Yang, Alfred X Sun

Sci Adv· October 2025

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Navigating Brain Organoid Maturation: From Benchmarking Frameworks to Multimodal Bioengineering Strategies.
Jingxiu Huang, Yingli Zhu, Jiong Tang, Yang Liu, Ming Lu, Alfred Xuyang Sun

Biomolecules· August 2025

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Vascular network-inspired diffusible scaffolds for engineering functional midbrain organoids.
Hongwei Cai, Chunhui Tian, Lei Chen, Yang Yang, Alfred Xuyang Sun

Cell Stem Cell· May 2025

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Shared and unique transcriptomic signatures of antidepressant and probiotics action in the mammalian brain.
Nirmala Arul Rayan, Jonathan Aow, Michelle Gek Liang Lim, Danusa Mar Arcego, Richard Ryan, Alfred Xuyang Sun

Mol Psychiatry· November 2024

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Repurposing of Zika virus live-attenuated vaccine (ZIKV-LAV) strains as oncolytic viruses targeting human glioblastoma multiforme cells.
Carla Bianca Luena Victorio, Wisna Novera, Arun Ganasarajah, Joanne Ong, Melisyaa Thomas, Alfred Xuyang Sun

J Transl Med· February 2024

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FUS-dependent microRNA deregulations identify TRIB2 as a druggable target for ALS motor neurons.
Wan Yun Ho, Li-Ling Chak, Jin-Hui Hor, Fujia Liu, Sandra Diaz-Garcia, Alfred Xuyang Sun

iScience· November 2023

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Midbrain organoids-development and applications in Parkinson's disease.
Hilary S Y Toh, Xin Yi Choo, Alfred Xuyang Sun

Oxf Open Neurosci· August 2023

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Evidence for a clathrin-independent endocytic pathway for APP internalization in the neuronal somatodendritic compartment.
Jonathan Aow, Tzu-Rung Huang, Yeek Teck Goh, Alfred Xuyang Sun, Gopal Thinakaran

Cell Rep· July 2023

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Unravelling Pathophysiology of Neurological and Psychiatric Complications of COVID-19 Using Brain Organoids.
Jing-Han Ng, Alfred Sun, Hyunsoo Shawn Je, Eng-King Tan

Neuroscientist· February 2023

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The role of tyrosine hydroxylase-dopamine pathway in Parkinson's disease pathogenesis.
Zhi Dong Zhou, Wuan Ting Saw, Patrick Ghim Hoe Ho, Zhi Wei Zhang, Li Zeng, Alfred Xu Yang Sun

Cell Mol Life Sci· November 2022

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Lewy Body-like Inclusions in Human Midbrain Organoids Carrying Glucocerebrosidase and α-Synuclein Mutations.
Junghyun Jo, Lin Yang, Hoang-Dai Tran, Weonjin Yu, Alfred Xuyang Sun

Ann Neurol· September 2021

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Evaluating Capture Sequence Performance for Single-Cell CRISPR Activation Experiments.
Xin Yi Choo, Yu Ming Lim, Khairunnisa Katwadi, Lynn Yap, Karl Tryggvason, Alfred Xuyang Sun

ACS Synth Biol· March 2021

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Potassium channel dysfunction in human neuronal models of Angelman syndrome.
Alfred Xuyang Sun, Qiang Yuan, Masahiro Fukuda, Weonjin Yu, Haidun Yan

Science· December 2019

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PD-linked CHCHD2 mutations impair CHCHD10 and MICOS complex leading to mitochondria dysfunction.
Wei Zhou, Dongrui Ma, Alfred Xuyang Sun, Hoang-Dai Tran, Dong-Liang Ma

Hum Mol Genet· April 2019

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Towards better cellular replacement therapies in Parkinson disease.
Alfred Xuyang Sun, Eng-King Tan

J Neurosci Res· February 2018

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3D neural tissue models: From spheroids to bioprinting.
Pei Zhuang, Alfred Xuyang Sun, Jia An, Chee Kai Chua, Sing Yian Chew

Biomaterials· February 2018

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Translational potential of human brain organoids.
Alfred X Sun, Huck-Hui Ng, Eng-King Tan

Ann Clin Transl Neurol· February 2018

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Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons.
Junghyun Jo, Yixin Xiao, Alfred Xuyang Sun, Engin Cukuroglu, Hoang-Dai Tran

Cell Stem Cell· August 2016

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Direct Induction and Functional Maturation of Forebrain GABAergic Neurons from Human Pluripotent Stem Cells.
Alfred Xuyang Sun, Qiang Yuan, Shawn Tan, Yixin Xiao, Danlei Wang

Cell Rep· August 2016

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Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways.
Brett T Staahl, Jiong Tang, Wei Wu, Alfred Sun, Aaron D Gitler

J Neurosci· June 2013

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MicroRNAs: regulators of neuronal fate.
Alfred X Sun, Gerald R Crabtree, Andrew S Yoo

Curr Opin Cell Biol· April 2013

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MicroRNA-mediated conversion of human fibroblasts to neurons.
Andrew S Yoo, Alfred X Sun, Li Li, Aleksandr Shcheglovitov, Thomas Portmann

Nature· July 2011

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Runx1 protects hematopoietic stem/progenitor cells from oncogenic insult.
Lena Motoda, Motomi Osato, Namiko Yamashita, Bindya Jacob, Lynnette Q Chen, Alfred X Sun

Stem Cells· December 2007

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