Publications by authors named "Ali Alhakim"

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General Considerations for Diversifying Heparin Drug Products by Improving the Current Heparin Manufacturing Process and Reintroducing Bovine Sourced Heparin to the US Market.
Ali Al-Hakim

Clin Appl Thromb Hemost· March 2022

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Sudden adult death syndrome in m.3243A>G-related mitochondrial disease: an unrecognized clinical entity in young, asymptomatic adults.
Yi Shiau Ng, John P Grady, Nichola Z Lax, John P Bourke, Charlotte L Alston, Ali Alhakim

Eur Heart J· August 2016

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The US regulatory and pharmacopeia response to the global heparin contamination crisis.
Anita Y Szajek, Edward Chess, Kristian Johansen, Gyöngyi Gratzl, Elaine Gray

Nat Biotechnol· June 2016

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FDA Approval: Ibrutinib for Patients with Previously Treated Mantle Cell Lymphoma and Previously Treated Chronic Lymphocytic Leukemia.
R Angelo de Claro, Karen M McGinn, Nicole Verdun, Shwu-Luan Lee, Haw-Jyh Chiu

Clin Cancer Res· August 2015

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FDA approval: ado-trastuzumab emtansine for the treatment of patients with HER2-positive metastatic breast cancer.
Laleh Amiri-Kordestani, Gideon M Blumenthal, Qiang Casey Xu, Lijun Zhang, Shenghui W Tang

Clin Cancer Res· September 2014

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Radium Ra 223 dichloride injection: U.S. Food and Drug Administration drug approval summary.
Paul G Kluetz, William Pierce, V Ellen Maher, Hui Zhang, Shenghui Tang

Clin Cancer Res· January 2014

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Characterization of currently marketed heparin products: key tests for LMWH quality assurance.
Hongping Ye, Timothy K Toby, Cynthia D Sommers, Houman Ghasriani, Michael L Trehy

J Pharm Biomed Anal· November 2013

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Characterization of currently marketed heparin products: analysis of heparin digests by RPIP-UHPLC-QTOF-MS.
Bo Wang, Lucinda F Buhse, Ali Al-Hakim, Michael T Boyne Ii, David A Keire

J Pharm Biomed Anal· October 2012

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Characterization of currently marketed heparin products: analysis of molecular weight and heparinase-I digest patterns.
Cynthia D Sommers, Hongping Ye, Richard E Kolinski, Moheb Nasr, Lucinda F Buhse

Anal Bioanal Chem· November 2011

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Identification of heparin samples that contain impurities or contaminants by chemometric pattern recognition analysis of proton NMR spectral data.
Qingda Zang, David A Keire, Lucinda F Buhse, Richard D Wood, Dinesh P Mital

Anal Bioanal Chem· August 2011

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Combining (1)H NMR spectroscopy and chemometrics to identify heparin samples that may possess dermatan sulfate (DS) impurities or oversulfated chondroitin sulfate (OSCS) contaminants.
Qingda Zang, David A Keire, Richard D Wood, Lucinda F Buhse, Christine M V Moore

J Pharm Biomed Anal· April 2011

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Class modeling analysis of heparin 1H NMR spectral data using the soft independent modeling of class analogy and unequal class modeling techniques.
Qingda Zang, David A Keire, Richard D Wood, Lucinda F Buhse, Christine M V Moore

Anal Chem· February 2011

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Characterization of currently marketed heparin products: key tests for quality assurance.
David A Keire, Hongping Ye, Michael L Trehy, Wei Ye, Richard E Kolinski

Anal Bioanal Chem· January 2011

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Determination of galactosamine impurities in heparin samples by multivariate regression analysis of their (1)H NMR spectra.
Qingda Zang, David A Keire, Richard D Wood, Lucinda F Buhse, Christine M V Moore

Anal Bioanal Chem· January 2011

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Characterization of currently marketed heparin products: reversed-phase ion-pairing liquid chromatography mass spectrometry of heparin digests.
Adam M Brustkern, Lucinda F Buhse, Moheb Nasr, Ali Al-Hakim, David A Keire

Anal Chem· December 2010

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Cysticercosis of the fourth ventricle causing sudden death: a case report and review of the literature.
Tibor Hortobágyi, Ali Alhakim, Olaf Biedrzycki, Vesna Djurovic, Jeewan Rawal

Pathol Oncol Res· March 2009

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Contaminated heparin associated with adverse clinical events and activation of the contact system.
Takashi Kei Kishimoto, Karthik Viswanathan, Tanmoy Ganguly, Subbiah Elankumaran, Sean Smith

N Engl J Med· June 2008

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Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events.
Marco Guerrini, Daniela Beccati, Zachary Shriver, Annamaria Naggi, Karthik Viswanathan

Nat Biotechnol· June 2008

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"Pseudosarcoma" in a pregnant woman.
Amarjit Anand, Eva Maria Tsapakis, Ali A Narvani, Ali Alhakim, Steve R Cannon

World J Surg Oncol· January 2007

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