Publications by authors named "Alice Lau"

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Distinct molecular patterns in R6/2 HD mouse brain: Insights from spatiotemporal transcriptomics.
Mara S Burns, Ricardo Miramontes, Jie Wu, Ravinder Gulia, Madhu S Saddala, Alice L Lau

Neuron· August 2025

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Dysregulation of protein SUMOylation networks in Huntington's disease R6/2 mouse striatum.
Marketta Kachemov, Vineet Vaibhav, Charlene Smith, Niveda Sundararaman, Marie Heath, Alice Lau

Brain· April 2025

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The High Prevalence of Orientia tsutsugamushi Among Wild Rodents and the Identification of Its Major Serotypes in Yamaguchi Prefecture, Japan, Where Scrub Typhus Patients Are Rarely Identified.
Abdelrahman Ahmed, Supriyono, Kazuki Kiuno, Nozomi Kurihara, Shohei Minami, Alice C C Lau

Microbiol Immunol· February 2025

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Aberrant splicing in Huntington's disease accompanies disrupted TDP-43 activity and altered m6A RNA modification.
Thai B Nguyen, Ricardo Miramontes, Carlos Chillon-Marinas, Roy Maimon, Sonia Vazquez-Sanchez, Alice L Lau

Nat Neurosci· February 2025

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Evaluating the effects of inorganic UV filter titanium dioxide nanoparticles (nano-TiO) on early life stages of scleractinian coral Acropora tumida.
Billy C T Cheung, Justin C H Leong, Eliana Y Y Chan, Taison K T Chang, Alice S U Lau

Mar Pollut Bull· December 2024

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Huntingtin contains an ubiquitin-binding domain and regulates lysosomal targeting of mitochondrial and RNA-binding proteins.
Gianna M Fote, Vinay V Eapen, Ryan G Lim, Clinton Yu, Lisa Salazar, Alice L Lau

Proc Natl Acad Sci U S A· August 2024

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Sialyl Lewis glycomimetics bearing an extended anionic chain targeting E- and P- selectin binding sites.
Audrey Belouin, Ryan D Simard, Mathieu Joyal, Wael Maharsy, Alice Lau

Bioorg Med Chem· January 2024

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Transplanted human neural stem cells rescue phenotypes in zQ175 Huntington's disease mice and innervate the striatum.
Sandra M Holley, Jack C Reidling, Carlos Cepeda, Jie Wu, Ryan G Lim, Alice Lau

Mol Ther· December 2023

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Aberrant splicing in Huntington's disease via disrupted TDP-43 activity accompanied by altered m6A RNA modification.
Thai B Nguyen, Ricardo Miramontes, Carlos Chillon-Marinas, Roy Maimon, Sonia Vazquez-Sanchez, Alice L Lau

bioRxiv· November 2023

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The dynamics of the microbiome in Ixodidae are shaped by tick ontogeny and pathogens in Sarawak, Malaysian Borneo.
Alice C C Lau, Wessam Mohamed Ahmed Mohamed, Ryo Nakao, Manabu Onuma, Yongjin Qiu

Microb Genom· February 2023

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Single-nuclei transcriptome analysis of Huntington disease iPSC and mouse astrocytes implicates maturation and functional deficits.
Andrea M Reyes-Ortiz, Edsel M Abud, Mara S Burns, Jie Wu, Sarah J Hernandez, Alice Lau

iScience· January 2023

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Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.
Ryan G Lim, Osama Al-Dalahmah, Jie Wu, Maxwell P Gold, Jack C Reidling, Alice Lau

Nat Commun· December 2022

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Workplace cessation support is associated with more abstinence in a workplace program in Hong Kong: A mixed-methods study.
Ziqiu Guo, Xue Weng, Alice Oi Sze Lau, Matthew Chak Hang Ng, Yongda Socrates Wu

Tob Induc Dis· December 2022

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Detection of a Babesia sp. genotype closely related to marsupial-associated Babesia spp. in male Haemaphysalis shimoga from Sarawak, Malaysian Borneo.
Alice Cc Lau, Yongjin Qiu, Mohamed Abdallah Mohamed Moustafa, Ryo Nakao, Michito Shimozuru

J Vet Med Sci· November 2022

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Diminished LC3-Associated Phagocytosis by Huntington's Disease Striatal Astrocytes.
Nicole M Wakida, Alice L Lau, Jessica Nguyen, Gladys Mae S Cruz, Gianna M Fote

J Huntingtons Dis· May 2022

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Detection of Tick-Borne Bacterial and Protozoan Pathogens in Ticks from the Zambia-Angola Border.
Yongjin Qiu, Martin Simuunza, Masahiro Kajihara, Joseph Ndebe, Ngonda Saasa, Alice C C Lau

Pathogens· May 2022

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Novel symbionts and potential human pathogens excavated from argasid tick microbiomes that are shaped by dual or single symbiosis.
Mohamed Abdallah Mohamed Moustafa, Wessam Mohamed Ahmed Mohamed, Alice C C Lau, Elisha Chatanga, Yongjin Qiu

Comput Struct Biotechnol J· April 2022

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Evidence of in Wild and Domestic Animals in the Kafue Ecosystem of Zambia.
Yongjin Qiu, David Squarre, Yukiko Nakamura, Alice C C Lau, Lavel Chinyama Moonga

Microorganisms· November 2021

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Huntington's disease mice and human brain tissue exhibit increased G3BP1 granules and TDP43 mislocalization.
Isabella I Sanchez, Thai B Nguyen, Whitney E England, Ryan G Lim, Anthony Q Vu, Lauren M Byrne, Alice L Lau

J Clin Invest· June 2021

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PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington's disease.
Eva L Morozko, Charlene Smith-Geater, Alejandro Mas Monteys, Subrata Pradhan, Ryan G Lim, Alice Lau

Proc Natl Acad Sci U S A· January 2021

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Detection of Sensu Lato and Relapsing Fever in Feeding Ticks and Rodents in Sarawak, Malaysia: New Geographical Records of and .
Alice C C Lau, Yongjin Qiu, Mohamed Abdallah Mohamed Moustafa, Ryo Nakao, Michito Shimozuru

Pathogens· October 2020

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Calcium Dynamics in Astrocytes During Cell Injury.
Nicole M Wakida, Veronica Gomez-Godinez, Huayan Li, Jessica Nguyen, Edward K Kim, Alice L Lau

Front Bioeng Biotechnol· August 2020

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Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington's Disease Knock-In Mouse Models.
Nicholas R Franich, Manuela Basso, Emily A André, Joseph Ochaba, Amit Kumar, Alice L Lau

J Huntingtons Dis· October 2019

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Longitudinal Biochemical Assay Analysis of Mutant Huntingtin Exon 1 Protein in R6/2 Mice.
Eva L Morozko, Joseph Ochaba, Sarah J Hernandez, Alice Lau, Isabella Sanchez

J Huntingtons Dis· October 2019

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IKKβ slows Huntington's disease progression in R6/1 mice.
Joseph Ochaba, Gianna Fote, Marketta Kachemov, Soe Thein, Sylvia Y Yeung, Alice L Lau

Proc Natl Acad Sci U S A· May 2019

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