Publications by authors named "Alison Schaefer"

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Stable nebulization and muco-trapping properties of regdanvimab/IN-006 support its development as a potent, dose-saving inhaled therapy for COVID-19.
Morgan D McSweeney, Ian Stewart, Zach Richardson, Hyunah Kang, Yoona Park, Cheolmin Kim, Karthik Tiruthani, Whitney Wolf, Alison Schaefer, Priya Kumar

Bioeng Transl Med· August 2022

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Engineering Decavalent, Sperm-Binding Laminin-IgG Hybrid Antibodies for Potent Non-Hormonal Contraception.
Alison Schaefer, Keiichiro Kushiro, Bhawana Shrestha, Yong Zhu, Alysha Panjwani

Adv Sci (Weinh)· October 2025

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Preferential apical infection and spread of human metapneumovirus highlights the importance of inhaled delivery of neutralizing monoclonal antibody to treat established infections.
Karthik Tiruthani, Madison P Card, Whitney Wolf, Limei Shen, Alison Schaefer

Proc Natl Acad Sci U S A· September 2025

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Vaginally-delivered fast-dissolving antibody tablets (FDAT) for on-demand non-hormonal contraception and multi-purpose protection.
Keiichiro Kushiro, Scott Hammers, Yong Zhu, Haley B Flowers, Lauren Dawson, Alison Schaefer

J Control Release· June 2025

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Bispecific Siglec-15/T cell antibody (STAB) activates T cells and suppresses pancreatic ductal adenocarcinoma and non-small cell lung tumors .
Limei Shen, Alison Schaefer, Justin Huckaby, Whitney Wolf, Samuel K Lai

Theranostics· May 2025

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ZMapp reduces diffusion of Ebola viral particles in fresh human cervicovaginal mucus.
Alison Schaefer, Bing Yang, Holly A Schroeder, Dimple Harit, Mike S Humphry

Emerg Microbes Infect· December 2024

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Impact of mAb-FcRn affinity on IgG transcytosis across human well-differentiated airway epithelium.
Kohei Togami, Whitney Wolf, Lucas C Olson, Madison Card, Limei Shen, Alison Schaefer

Front Immunol· October 2024

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Siglec15/TGF-β bispecific antibody mediates synergistic anti-tumor response against 4T1 triple negative breast cancer in mice.
Limei Shen, Alison M Schaefer, Karthik Tiruthani, Whitney Wolf, Samuel K Lai

Bioeng Transl Med· September 2024

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Engineering a "muco-trapping" ACE2-immunoglobulin hybrid with picomolar affinity as an inhaled, pan-variant immunotherapy for COVID-19.
Karthik Tiruthani, Carlos Cruz-Teran, Jasper F W Chan, Alice Ma, Morgan McSweeney, Alison Schaefer

Bioeng Transl Med· July 2024

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Inhaled "Muco-Trapping" Monoclonal Antibody Effectively Treats Established Respiratory Syncytial Virus (RSV) Infections.
Morgan D McSweeney, Sarhad Alnajjar, Alison M Schaefer, Zach Richardson, Whitney Wolf

Adv Sci (Weinh)· March 2024

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Broadly neutralizing antibodies consistently trap HIV-1 in fresh cervicovaginal mucus from select individuals.
Alison Schaefer, Bing Yang, Holly A Schroeder, Dimple Harit, Mike S Humphry

Acta Biomater· October 2023

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The biophysical principles underpinning muco-trapping functions of antibodies.
Alison Schaefer, Samuel K Lai

Hum Vaccin Immunother· April 2022

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Hexavalent sperm-binding IgG antibody released from vaginal film for development of potent on-demand nonhormonal female contraception.
Bhawana Shrestha, Kathleen Vincent, Alison Schaefer, Yong Zhu, Gracie Vargas

Proc Natl Acad Sci U S A· November 2021

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Engineering sperm-binding IgG antibodies for the development of an effective nonhormonal female contraception.
Bhawana Shrestha, Alison Schaefer, Yong Zhu, Jamal Saada, Timothy M Jacobs

Sci Transl Med· August 2021

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Engineering tetravalent IgGs with enhanced agglutination potencies for trapping vigorously motile sperm in mucin matrix.
Bhawana Shrestha, Alison Schaefer, Elizabeth C Chavez, Alexander J Kopp, Timothy M Jacobs

Acta Biomater· November 2020

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LPS-binding IgG arrests actively motile Salmonella Typhimurium in gastrointestinal mucus.
Holly A Schroeder, Jay Newby, Alison Schaefer, Babu Subramani, Alan Tubbs

Mucosal Immunol· September 2020

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The Cervicovaginal Microbiota-Host Interaction Modulates Chlamydia trachomatis Infection.
Vonetta L Edwards, Steven B Smith, Elias J McComb, Jeanne Tamarelle, Bing Ma, Alison M Schaefer

mBio· August 2019

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Engineering Polymer-Binding Bispecific Antibodies for Enhanced Pretargeted Delivery of Nanoparticles to Mucus-Covered Epithelium.
Justin T Huckaby, Christina L Parker, Tim M Jacobs, Alison Schaefer, Daniel Wadsworth

Angew Chem Int Ed Engl· April 2019

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Herpes simplex virus-binding IgG traps HSV in human cervicovaginal mucus across the menstrual cycle and diverse vaginal microbial composition.
Holly A Schroeder, Kenetta L Nunn, Alison Schaefer, Christine E Henry, Felix Lam

Mucosal Immunol· September 2018

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Convolutional neural networks automate detection for tracking of submicron-scale particles in 2D and 3D.
Jay M Newby, Alison M Schaefer, Phoebe T Lee, M Gregory Forest, Samuel K Lai

Proc Natl Acad Sci U S A· September 2018

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ZMapp Reinforces the Airway Mucosal Barrier Against Ebola Virus.
Bing Yang, Alison Schaefer, Ying-Ying Wang, Justin McCallen, Phoebe Lee

J Infect Dis· August 2018

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Stereolithography-Based 3D Printed "Pillar Plates" that Minimizes Fluid Transfers During Enzyme Linked Immunosorbent Assays.
Justin D McCallen, Alison Schaefer, Phoebe Lee, Loretta Hing, Samuel K Lai

Ann Biomed Eng· April 2017

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Stimulated rejuvenation of dormant Aulacoseira granulata (Bacillariophyta) by Gloeocystis planctonica (Chlorophyta) in a eutrophic river.
David Poister, Alison Schaefer, Andrew Baert, John Tracey, Katelyn Richards

J Phycol· April 2015

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