Publications by authors named "Alison Slaughter"

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HIV-1 Integrase Binds the Viral RNA Genome and Is Essential during Virion Morphogenesis.
Jacques J Kessl, Sebla B Kutluay, Dana Townsend, Stephanie Rebensburg, Alison Slaughter

Cell· August 2016

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The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency.
Lei Feng, Venkatasubramanian Dharmarajan, Erik Serrao, Ashley Hoyte, Ross C Larue, Alison Slaughter

ACS Chem Biol· May 2016

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HIV-1 integrase multimerization as a therapeutic target.
Lei Feng, Ross C Larue, Alison Slaughter, Jacques J Kessl, Mamuka Kvaratskhelia

Curr Top Microbiol Immunol· July 2015

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The mechanism of H171T resistance reveals the importance of Nδ-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase.
Alison Slaughter, Kellie A Jurado, Nanjie Deng, Lei Feng, Jacques J Kessl

Retrovirology· November 2014

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A critical role of the C-terminal segment for allosteric inhibitor-induced aberrant multimerization of HIV-1 integrase.
Nikoloz Shkriabai, Venkatasubramanian Dharmarajan, Alison Slaughter, Jacques J Kessl, Ross C Larue

J Biol Chem· September 2014

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A new class of multimerization selective inhibitors of HIV-1 integrase.
Amit Sharma, Alison Slaughter, Nivedita Jena, Lei Feng, Jacques J Kessl

PLoS Pathog· May 2014

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BET proteins promote efficient murine leukemia virus integration at transcription start sites.
Amit Sharma, Ross C Larue, Matthew R Plumb, Nirav Malani, Frances Male, Alison Slaughter

Proc Natl Acad Sci U S A· July 2013

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Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation.
Kellie A Jurado, Hao Wang, Alison Slaughter, Lei Feng, Jacques J Kessl

Proc Natl Acad Sci U S A· May 2013

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The A128T resistance mutation reveals aberrant protein multimerization as the primary mechanism of action of allosteric HIV-1 integrase inhibitors.
Lei Feng, Amit Sharma, Alison Slaughter, Nivedita Jena, Yasuhiro Koh

J Biol Chem· May 2013

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Multimode, cooperative mechanism of action of allosteric HIV-1 integrase inhibitors.
Jacques J Kessl, Nivedita Jena, Yasuhiro Koh, Humeyra Taskent-Sezgin, Alison Slaughter

J Biol Chem· May 2012

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