Publications by authors named "Alja Oblak"

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Glycolipid-based TLR4 Modulators and Fluorescent Probes: Rational Design, Synthesis, and Biological Properties.
Carlotta Ciaramelli, Valentina Calabrese, Stefania E Sestito, Lucia Pérez-Regidor, Javier Klett, Alja Oblak

Chem Biol Drug Des· August 2016

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Molecular Basis of the Functional Differences between Soluble Human Versus Murine MD-2: Role of Val135 in Transfer of Lipopolysaccharide from CD14 to MD-2.
Jožica Vašl, Alja Oblak, Tina T Peternelj, Javier Klett, Sonsoles Martín-Santamaría

J Immunol· March 2016

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MD-2 determinants of nickel and cobalt-mediated activation of human TLR4.
Alja Oblak, Jelka Pohar, Roman Jerala

PLoS One· February 2016

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Activation of Human Toll-like Receptor 4 (TLR4)·Myeloid Differentiation Factor 2 (MD-2) by Hypoacylated Lipopolysaccharide from a Clinical Isolate of Burkholderia cenocepacia.
Flaviana Di Lorenzo, Łukasz Kubik, Alja Oblak, Nicola Ivan Lorè, Cristina Cigana

J Biol Chem· August 2015

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Species-specific activation of TLR4 by hypoacylated endotoxins governed by residues 82 and 122 of MD-2.
Alja Oblak, Roman Jerala

PLoS One· May 2015

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The molecular mechanism of species-specific recognition of lipopolysaccharides by the MD-2/TLR4 receptor complex.
Alja Oblak, Roman Jerala

Mol Immunol· February 2015

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Trehalose- and glucose-derived glycoamphiphiles: small-molecule and nanoparticle Toll-like receptor 4 (TLR4) modulators.
Julio Rodriguez Lavado, Stefania E Sestito, Roberto Cighetti, Eva M Aguilar Moncayo, Alja Oblak

J Med Chem· November 2014

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Development of αGlcN(1↔1)αMan-based lipid A mimetics as a novel class of potent Toll-like receptor 4 agonists.
Florian Adanitsch, Simon Ittig, Johannes Stöckl, Alja Oblak, Mira Haegman

J Med Chem· October 2014

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A bistable genetic switch based on designable DNA-binding domains.
Tina Lebar, Urban Bezeljak, Anja Golob, Miha Jerala, Lucija Kadunc, Alja Oblak

Nat Commun· September 2014

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Tetraacylated lipid A and paclitaxel-selective activation of TLR4/MD-2 conferred through hydrophobic interactions.
Nusa Resman, Alja Oblak, Theresa L Gioannini, Jerrold P Weiss, Roman Jerala

J Immunol· February 2014

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Conformationally constrained lipid A mimetics for exploration of structural basis of TLR4/MD-2 activation by lipopolysaccharide.
Daniel Artner, Alja Oblak, Simon Ittig, Jose Antonio Garate, Simon Horvat

ACS Chem Biol· November 2013

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Delivery system for the enhanced efficiency of immunostimulatory nucleic acids.
Anze Smole, Alenka Kuznik Krajnik, Alja Oblak, Nina Pirher, Roman Jerala

Innate Immun· February 2013

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Toll-like receptor 4 activation in cancer progression and therapy.
Alja Oblak, Roman Jerala

Clin Dev Immunol· March 2012

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Novel roles of lysines 122, 125, and 58 in functional differences between human and murine MD-2.
Jozica Vasl, Alja Oblak, Theresa L Gioannini, Jerrold P Weiss, Roman Jerala

J Immunol· October 2009

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Essential roles of hydrophobic residues in both MD-2 and toll-like receptor 4 in activation by endotoxin.
Nusa Resman, Jozica Vasl, Alja Oblak, Primoz Pristovsek, Theresa L Gioannini

J Biol Chem· May 2009

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