Publications by authors named "Allen C Chen"

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Population pharmacokinetics and exposure-response analysis of durvalumab in patients with resectable stage II to IIIB (N2) NSCLC in the phase III AEGEAN study.
Xiaoying Zhao, Junjie Ding, Jiajia Zhao, Ling Zhang, Aburough Abegesah, Allen C Chen

Br J Clin Pharmacol· November 2025

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Machine learning modeling of patient health signals informs long-term survival on immune checkpoint inhibitor therapy.
Gerald J Sun, Gustavo Arango-Argoty, Gary J Doherty, Damian E Bikiel, Dejan Pavlovic, Allen C Chen

iScience· September 2024

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Specificity of ABCA7-mediated cell lipid efflux.
Antonino Picataggi, Amrith Rodrigues, Debra A Cromley, Hu Wang, Joel P Wiener, Allen C Chen

Biochim Biophys Acta Mol Cell Biol Lipids· July 2022

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Immune Checkpoint Blockade in Advanced Renal-Cell Carcinoma.
Robert J Motzer, M Brent McHenry, Allen C Chen

N Engl J Med· July 2018

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Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma.
Robert J Motzer, Nizar M Tannir, David F McDermott, Osvaldo Arén Frontera, Bohuslav Melichar, Allen C Chen, M Brent McHenry

N Engl J Med· April 2018

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First-Line Nivolumab in Stage IV or Recurrent Non-Small-Cell Lung Cancer.
David P Carbone, Martin Reck, Luis Paz-Ares, Benjamin Creelan, Leora Horn, Allen C Chen

N Engl J Med· June 2017

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Nivolumab in Combination With Platinum-Based Doublet Chemotherapy for First-Line Treatment of Advanced Non-Small-Cell Lung Cancer.
Naiyer A Rizvi, Matthew D Hellmann, Julie R Brahmer, Rosalyn A Juergens, Hossein Borghaei, Allen C Chen

J Clin Oncol· September 2016

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Fluorescent Analogue of Batimastat Enables Imaging of α-Secretase in Living Cells.
Geoffray Leriche, Allen C Chen, Sumin Kim, Dennis J Selkoe, Jerry Yang

ACS Chem Neurosci· January 2016

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Physical and functional interaction between the α- and γ-secretases: A new model of regulated intramembrane proteolysis.
Allen C Chen, Sumin Kim, Nina Shepardson, Sarvagna Patel, Soyon Hong

J Cell Biol· December 2015

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Aph-1 associates directly with full-length and C-terminal fragments of gamma-secretase substrates.
Allen C Chen, Lucie Y Guo, Beth L Ostaszewski, Dennis J Selkoe, Matthew J LaVoie

J Biol Chem· April 2010

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Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1.
Tracy L Young-Pearse, Allen C Chen, Rui Chang, Cesar Marquez, Dennis J Selkoe

Neural Dev· June 2008

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Response to: Pardossi-Piquard et al., "Presenilin-Dependent Transcriptional Control of the Abeta-Degrading Enzyme Neprilysin by Intracellular Domains of betaAPP and APLP." Neuron 46, 541-554.
Allen C Chen, Dennis J Selkoe

Neuron· February 2007

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Complications of androgen-deprivation therapy in men with prostate cancer.
Allen C Chen, Daniel P Petrylak

Curr Urol Rep· May 2005

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Prostate-specific antigen, sex steroid hormones, and the insulin-like growth factor axis in U.S.-born, Jamaican, and Haitian black men: a pilot study.
Allen C Chen, Richard J MacChia, Francine Conway, Carol Magai, Manisha Desai

Urology· September 2004

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Complications of androgen deprivation therapy in men with prostate cancer.
Allen C Chen, Daniel P Petrylak

Curr Oncol Rep· May 2004

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The "skinny" on obesity and prostate cancer prognosis.
Alfred I Neugut, Allen C Chen, Daniel P Petrylak

J Clin Oncol· February 2004

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