Publications by authors named "Allen Krouse"

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cMPL-based purification and depletion of human hematopoietic stem cells: implications for pretransplant conditioning.
Daisuke Araki, So Gun Hong, Nathaniel Linde, Bryan Fisk, Neelam Redekar, Allen Krouse

Blood· June 2025

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BCL11A +58/+55 enhancer-editing facilitates HSPC engraftment and HbF induction in rhesus macaques conditioned with a CD45 antibody-drug conjugate.
Selami Demirci, Jing Zeng, Rahul Palchaudhuri, Chuanfeng Wu, Diana M Abraham, Allen E Krouse

Cell Stem Cell· February 2025

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cMPL-Based Purification and Depletion of Human Hematopoietic Stem Cells: Implications for Pre-Transplant Conditioning.
Daisuke Araki, Sogun Hong, Nathaniel Linde, Bryan Fisk, Neelam Redekar, Allen Krouse

bioRxiv· February 2024

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Fertility-preserving myeloablative conditioning using single-dose CD117 antibody-drug conjugate in a rhesus gene therapy model.
Naoya Uchida, Ulana Stasula, Selami Demirci, Paula Germino-Watnick, Malikiya Hinds, Allen E Krouse

Nat Commun· October 2023

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Pre-existing immunity does not impair the engraftment of CRISPR-Cas9-edited cells in rhesus macaques conditioned with busulfan or radiation.
Khaled Essawi, Waleed Hakami, Muhammad Behroz Naeem Khan, Reid Martin, Jing Zeng, Allen E Krouse

Mol Ther Methods Clin Dev· June 2023

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Comparison of busulfan and total body irradiation conditioning on hematopoietic clonal dynamics following lentiviral gene transfer in rhesus macaques.
Diana M Abraham, Richard J Lozano, Xavi Guitart, Jialiu A Liang, Ryland D Mortlock, Allen Krouse

Mol Ther Methods Clin Dev· March 2023

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Forced enhancer-promoter rewiring to alter gene expression in animal models.
Scott A Peslak, Selami Demirci, Vemika Chandra, Byoung Ryu, Saurabh K Bhardwaj, Allen E Krouse

Mol Ther Nucleic Acids· March 2023

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Sustained fetal hemoglobin induction in vivo is achieved by interference and coexpressed truncated erythropoietin receptor.
Naoya Uchida, Francesca Ferrara, Claire M Drysdale, Morgan Yapundich, Jackson Gamer, Allen E Krouse

Sci Transl Med· April 2021

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Preclinical evaluation for engraftment of CD34 cells gene-edited at the sickle cell disease locus in xenograft mouse and non-human primate models.
Naoya Uchida, Linhong Li, Tina Nassehi, Claire M Drysdale, Morgan Yapundich, Allen E Krouse

Cell Rep Med· April 2021

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Comparative engraftment and clonality of macaque HSPCs expanded on human umbilical vein endothelial cells versus non-expanded cells.
Sandeep K Srivastava, Lauren L Truitt, Chuanfeng Wu, Adam Glaser, Daniel J Nolan, Allen Krouse

Mol Ther Methods Clin Dev· March 2021

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BCL11A enhancer-edited hematopoietic stem cells persist in rhesus monkeys without toxicity.
Selami Demirci, Jing Zeng, Yuxuan Wu, Naoya Uchida, Anne H Shen, Allen E Krouse

J Clin Invest· December 2020

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Intrabone transplantation of CD34+ cells with optimized delivery does not enhance engraftment in a rhesus macaque model.
Kate Stringaris, Robert F Hoyt, Jan K Davidson-Moncada, Jeremy M Pantin, John F Tisdale, Allen Krouse

Blood Adv· December 2020

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Clonal tracking of erythropoiesis in rhesus macaques.
Xing Fan, Chuanfeng Wu, Lauren L Truitt, Diego A Espinoza, Stephanie Sellers, Allen Krouse

Haematologica· July 2020

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Development of a forward-oriented therapeutic lentiviral vector for hemoglobin disorders.
Naoya Uchida, Matthew M Hsieh, Lydia Raines, Juan J Haro-Mora, Selami Demirci, Allen E Krouse

Nat Commun· October 2019

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Busulfan Combined with Immunosuppression Allows Efficient Engraftment of Gene-Modified Cells in a Rhesus Macaque Model.
Naoya Uchida, Tina Nassehi, Claire M Drysdale, Jackson Gamer, Morgan Yapundich, Allen E Krouse

Mol Ther· September 2019

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Fetal hemoglobin and F-cell variance in mobilized CD34 cell-transplanted rhesus monkeys.
Selami Demirci, Juan J Haro Mora, Morgan Yapundich, Claire Drysdale, Jackson Gamer, Allen E Krouse

Exp Hematol· July 2019

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Aberrant Clonal Hematopoiesis following Lentiviral Vector Transduction of HSPCs in a Rhesus Macaque.
Diego A Espinoza, Xing Fan, Di Yang, Stefan F Cordes, Lauren L Truitt, Allen Krouse

Mol Ther· June 2019

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Barcoding of Macaque Hematopoietic Stem and Progenitor Cells: A Robust Platform to Assess Vector Genotoxicity.
Idalia M Yabe, Lauren L Truitt, Diego A Espinoza, Chuanfeng Wu, Samson Koelle, Allen Krouse

Mol Ther Methods Clin Dev· December 2018

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The impact of aging on primate hematopoiesis as interrogated by clonal tracking.
Kyung-Rok Yu, Diego A Espinoza, Chuanfeng Wu, Lauren Truitt, Tae-Hoon Shin, Allen Krouse

Blood· March 2018

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Bone Marrow as a Hematopoietic Stem Cell Source for Gene Therapy in Sickle Cell Disease: Evidence from Rhesus and SCD Patients.
Naoya Uchida, Atsushi Fujita, Matthew M Hsieh, Aylin C Bonifacino, Allen E Krouse

Hum Gene Ther Clin Dev· September 2017

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Total body irradiation must be delivered at high dose for efficient engraftment and tolerance in a rhesus stem cell gene therapy model.
Naoya Uchida, R Patrick Weitzel, Anna Shvygin, Luke P Skala, Lydia Raines, Allen E Krouse

Mol Ther Methods Clin Dev· September 2016

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Discordance in lymphoid tissue recovery following stem cell transplantation in rhesus macaques: an in vivo imaging study.
Robert E Donahue, Sharat Srinivasula, Naoya Uchida, Insook Kim, Alexis St Claire, Allen E Krouse

Blood· December 2015

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Integration-specific In Vitro Evaluation of Lentivirally Transduced Rhesus CD34(+) Cells Correlates With In Vivo Vector Copy Number.
Naoya Uchida, Molly E Evans, Matthew M Hsieh, Aylin C Bonifacino, Allen E Krouse

Mol Ther Nucleic Acids· September 2013

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