Publications by authors named "Allison Amore"

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The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS.
Michele M Maxwell, Elizabeth M Tomkinson, Johnathan Nobles, John W Wizeman, Allison M Amore

Hum Mol Genet· October 2011

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A brain-permeable small molecule reduces neuronal cholesterol by inhibiting activity of sirtuin 2 deacetylase.
David M Taylor, Uma Balabadra, Zhongmin Xiang, Ben Woodman, Sarah Meade, Allison Amore

ACS Chem Biol· June 2011

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Evaluation of histone deacetylases as drug targets in Huntington's disease models. Study of HDACs in brain tissues from R6/2 and CAG140 knock-in HD mouse models and human patients and in a neuronal HD cell model.
Luisa Quinti, Vanita Chopra, Dante Rotili, Sergio Valente, Allison Amore

PLoS Curr· September 2010

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SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis.
Ruth Luthi-Carter, David M Taylor, Judit Pallos, Emmanuel Lambert, Allison Amore

Proc Natl Acad Sci U S A· April 2010

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Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease.
Tiago Fleming Outeiro, Eirene Kontopoulos, Stephen M Altmann, Irina Kufareva, Katherine E Strathearn, Allison M Amore

Science· July 2007

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Pharmacological inhibition of PARP-1 reduces alpha-synuclein- and MPP+-induced cytotoxicity in Parkinson's disease in vitro models.
Tiago Fleming Outeiro, Tom N Grammatopoulos, Steven Altmann, Allison Amore, David G Standaert

Biochem Biophys Res Commun· June 2007

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Discovery of a novel small-molecule targeting selective clearance of mutant huntingtin fragments.
Myra Coufal, Michele M Maxwell, Deborah E Russel, Allison M Amore, Stephen M Altmann

J Biomol Screen· April 2007

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