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Publications by authors named "Allison R Gregro"

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VU6005806/AZN-00016130, an advanced M positive allosteric modulator (PAM) profiled as a potential preclinical development candidate.
Darren W Engers, Bruce J Melancon, Allison R Gregro, Jeanette L Bertron, Sean R Bollinger

Bioorg Med Chem Lett· July 2019


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First demonstration of cerebrospinal fluid and plasma A beta lowering with oral administration of a beta-site amyloid precursor protein-cleaving enzyme 1 inhibitor in nonhuman primates.
Sethu Sankaranarayanan, Marie A Holahan, Dennis Colussi, Ming-Chih Crouthamel, Viswanath Devanarayan, Allison R Gregro

J Pharmacol Exp Ther· January 2009


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Evolution of tertiary carbinamine BACE-1 inhibitors: Abeta reduction in rhesus CSF upon oral dosing.
Philippe G Nantermet, Hemaka A Rajapakse, Mathew G Stanton, Shaun R Stauffer, James C Barrow, Allison R Gregro

ChemMedChem· January 2009


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