Publications by authors named "Alpha A Fowler"

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Vitamin C: Rationale for Its Use in Sepsis-Induced Acute Respiratory Distress Syndrome (ARDS).
Alpha A Fowler

Antioxidants (Basel)· January 2024

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Biological Effects of Intravenous Vitamin C on Neutrophil Extracellular Traps and the Endothelial Glycocalyx in Patients with Sepsis-Induced ARDS.
Xian Qiao, Markos G Kashiouris, Michael L'Heureux, Bernard J Fisher, Stefan W Leichtle, Alpha A Fowler

Nutrients· October 2022

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Opportunities for improved clinical trial designs in acute respiratory distress syndrome.
Katherine D Wick, Neil R Aggarwal, Martha A Q Curley, Alpha A Fowler, Samir Jaber

Lancet Respir Med· September 2022

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Vitamin C in Critically Ill Patients: An Updated Systematic Review and Meta-Analysis.
Dhan Bahadur Shrestha, Pravash Budhathoki, Yub Raj Sedhai, Sujit Kumar Mandal, Shreeja Shikhrakar, Alpha A Fowler

Nutrients· October 2021

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Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial.
Jonathan E Sevransky, Richard E Rothman, David N Hager, Gordon R Bernard, Samuel M Brown, Alpha A Fowler

JAMA· February 2021

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In response: Letter on update to the Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) protocol.
Christopher J Lindsell, Anna McGlothlin, Samuel Nwosu, Todd W Rice, Alex Hall, Alpha A Fowler

Trials· April 2020

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Vitamin C for Sepsis and Acute Respiratory Failure-Reply.
Alpha A Fowler, Bernard J Fisher, Markos G Kashiouris

JAMA· February 2020

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The Emerging Role of Vitamin C as a Treatment for Sepsis.
Markos G Kashiouris, Michael L'Heureux, Casey A Cable, Bernard J Fisher, Stefan W Leichtle, Alpha A Fowler

Nutrients· January 2020

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Update to the Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) protocol: statistical analysis plan for a prospective, multicenter, double-blind, adaptive sample size, randomized, placebo-controlled, clinical trial.
Christopher J Lindsell, Anna McGlothlin, Samuel Nwosu, Todd W Rice, Alex Hall, Alpha A Fowler

Trials· December 2019

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Temporal map of the pig polytrauma plasma proteome with fluid resuscitation and intravenous vitamin C treatment.
Emmanuel K Cudjoe, Zaneera H Hassan, Le Kang, Penny S Reynolds, Bernard J Fisher, Alpha A Fowler

J Thromb Haemost· November 2019

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Supply Chain Delays in Antimicrobial Administration After the Initial Clinician Order and Mortality in Patients With Sepsis.
Markos G Kashiouris, Zachary Zemore, Zachary Kimball, Christos Stefanou, Alpha A Fowler

Crit Care Med· October 2019

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Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial.
Alpha A Fowler, Jonathon D Truwit, R Duncan Hite, Peter E Morris, Christine DeWilde

JAMA· October 2019

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Hematopoietic stem cell mobilization following PD-1 blockade: Cytokine release syndrome after transplantation managed with ascorbic acid.
Ariel Sindel, Trevor Taylor, Alden Chesney, William Clark, Alpha A Fowler

Eur J Haematol· August 2019

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The Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) Protocol: a prospective, multi-center, double-blind, adaptive sample size, randomized, placebo-controlled, clinical trial.
David N Hager, Michael H Hooper, Gordon R Bernard, Laurence W Busse, E Wesley Ely, Alpha A Fowler

Trials· April 2019

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Interventional vitamin C: A strategy for attenuation of coagulopathy and inflammation in a swine multiple injuries model.
Penny S Reynolds, Bernard J Fisher, Jacquelyn McCarter, Christopher Sweeney, Erika J Martin, Evan Fowler, Alpha A Fowler

J Trauma Acute Care Surg· July 2018

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Attenuation of Red Blood Cell Storage Lesions with Vitamin C.
Kimberly Sanford, Bernard J Fisher, Evan Fowler, Alpha A Fowler, Ramesh Natarajan

Antioxidants (Basel)· July 2017

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Intravenous Vitamin C Administered as Adjunctive Therapy for Recurrent Acute Respiratory Distress Syndrome.
Amit Bharara, Catherine Grossman, Daniel Grinnan, Aamer Syed, Bernard Fisher, Alpha A Berry Fowler

Case Rep Crit Care· November 2016

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Vitamin C promotes wound healing through novel pleiotropic mechanisms.
Bassem M Mohammed, Bernard J Fisher, Donatas Kraskauskas, Susan Ward, Jennifer S Wayne, Alpha A Fowler

Int Wound J· August 2016

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Conservative fluid management prevents age-associated ventilator induced mortality.
Joseph A Herbert, Michael S Valentine, Nivi Saravanan, Matthew B Schneck, Ramana Pidaparti, Alpha A Fowler

Exp Gerontol· August 2016

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Ascorbate-dependent vasopressor synthesis: a rationale for vitamin C administration in severe sepsis and septic shock?
Anitra C Carr, Geoffrey M Shaw, Alpha A Fowler, Ramesh Natarajan

Crit Care· November 2015

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Resolution of sterile inflammation: role for vitamin C.
Bassem M Mohammed, Bernard J Fisher, Quoc K Huynh, Dayanjan S Wijesinghe, Charles E Chalfant, Alpha A Fowler

Mediators Inflamm· June 2015

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Lung cancer screening with low-dose computed tomography: an analysis of the MEDCAC decision.
Mark S Parker, Robert C Groves, Alpha A Fowler, Ray W Shepherd, Anthony D Cassano

J Thorac Imaging· January 2015

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Attenuation of sepsis-induced organ injury in mice by vitamin C.
Bernard J Fisher, Donatas Kraskauskas, Erika J Martin, Daniela Farkas, Puneet Puri, Alpha A Fowler

JPEN J Parenter Enteral Nutr· September 2014

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Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis.
Alpha A Fowler, Aamer A Syed, Shelley Knowlson, Robin Sculthorpe, Don Farthing

J Transl Med· January 2014

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Vitamin C: a novel regulator of neutrophil extracellular trap formation.
Bassem M Mohammed, Bernard J Fisher, Donatas Kraskauskas, Daniela Farkas, Donald F Brophy, Alpha A Fowler

Nutrients· August 2013

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