Publications by authors named "Alvin H-K Cheung"

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Targeting of the mA eraser ALKBH5 suppresses stemness and chemoresistance of colorectal cancer.
Heming Zhou, Huarong Chen, Weixin Liu, Cong Liang, Shiyan Wang, Alvin Ho Kwan Cheung, Henley Cheung

Nat Commun· December 2025

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Spatial and functional dissection of cancer-associated fibroblasts-mediated immune modulation in H. pylori-associated gastric cancer.
Bonan Chen, Hongzhen Tang, Xiaohong Zheng, Fuda Xie, Peiyao Yu, Alvin H K Cheung, Justin Chak Ting Cheung

Mol Cancer· November 2025

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STK3 is a transcriptional target of YAP1 and a hub component in the crosstalk between Hippo and Wnt signaling pathways during gastric carcinogenesis.
Fuda Xie, Yang Lyu, Bonan Chen, Hoi Wing Leung, Peiyao Yu, Alvin H K Cheung

Mol Cancer· July 2025

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Intestinal TM6SF2 protects against metabolic dysfunction-associated steatohepatitis through the gut-liver axis.
Xiang Zhang, Harry Cheuk-Hay Lau, Suki Ha, Chuanfa Liu, Cong Liang, Alvin Ho Kwan Cheung

Nat Metab· January 2025

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Author Correction: Intestinal TM6SF2 protects against metabolic dysfunction-associated steatohepatitis through the gut-liver axis.
Xiang Zhang, Harry Cheuk-Hay Lau, Suki Ha, Chuanfa Liu, Cong Liang, Alvin Ho Kwan Cheung

Nat Metab· January 2025

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Germline Human Leukocyte Antigen Status is Associated With Immunotherapy-Induced Pneumonitis and Treatment Response in Patients With Non-Small Cell Lung Cancer With High Programmed Death-Ligand 1 Expression.
Alvin H K Cheung, Zeta Mui, Walter W Yeung, Chit Chow, Mandy F Yu

JTO Clin Res Rep· January 2025

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FOXP4 Is a Direct YAP1 Target That Promotes Gastric Cancer Stemness and Drives Metastasis.
Xiaoli Liu, Bonan Chen, Fuda Xie, Kit Yee Wong, Alvin H K Cheung

Cancer Res· November 2024

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VSTM2A reverses immunosuppression in colorectal cancer by antagonizing the PD-L1/PD-1 interaction.
Yujuan Dong, Jiaxun Jade Liu, Yunfei Zhou, Wei Kang, Shanglin Li, Alvin H K Cheung

Mol Ther· November 2024

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VSTM2A reverses immunosuppression in colorectal cancer by antagonizing the PD-L1/PD-1 interaction.
Yujuan Dong, Jiaxun Jade Liu, Yunfei Zhou, Wei Kang, Shanglin Li, Alvin H K Cheung

Mol Ther· November 2024

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Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice.
Kaili Fu, Alvin Ho Kwan Cheung, Chi Chun Wong, Weixin Liu, Yunfei Zhou

Cell· November 2024

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RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis.
Danyu Chen, Fenfen Ji, Qiming Zhou, Henley Cheung, Yasi Pan, Alvin H-K Cheung

Cancer Res· September 2024

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High Soluble Fiber Promotes Colorectal Tumorigenesis Through Modulating Gut Microbiota and Metabolites in Mice.
Jia Yang, Hong Wei, Yufeng Lin, Eagle S H Chu, Yunfei Zhou, Alvin H K Cheung

Gastroenterology· February 2024

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The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma.
Xiaoxi Pan, Khalid AbdulJabbar, Jose Coelho-Lima, Anca-Ioana Grapa, Hanyun Zhang, Alvin Ho Kwan Cheung

Nat Cancer· February 2024

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Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice.
Kaili Fu, Alvin Ho Kwan Cheung, Chi Chun Wong, Weixin Liu, Yunfei Zhou

Cell· February 2024

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The molecular classification of cancer-associated fibroblasts on a pan-cancer single-cell transcriptional atlas.
Bonan Chen, Wai Nok Chan, Fuda Xie, Chun Wai Mui, Xiaoli Liu, Alvin H K Cheung

Clin Transl Med· December 2023

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H. pylori-induced NF-κB-PIEZO1-YAP1-CTGF axis drives gastric cancer progression and cancer-associated fibroblast-mediated tumour microenvironment remodelling.
Bonan Chen, Xiaoli Liu, Peiyao Yu, Fuda Xie, Johnny S H Kwan, Alvin H K Cheung

Clin Transl Med· November 2023

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MCM6 is a critical transcriptional target of YAP to promote gastric tumorigenesis and serves as a therapeutic target.
Yifei Wang, Huarong Chen, Weixin Liu, Huan Yan, Yihan Zhang, Alvin H K Cheung

Theranostics· October 2022

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Targeting the Hippo Pathway in Gastric Cancer and Other Malignancies in the Digestive System: From Bench to Bedside.
Xiaoli Liu, Yifei Wang, Bonan Chen, Wai Nok Chan, Chun Wai Mui, Alvin H K Cheung

Biomedicines· October 2022

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Fangchinoline inhibits non-small cell lung cancer metastasis by reversing epithelial-mesenchymal transition and suppressing the cytosolic ROS-related Akt-mTOR signaling pathway.
Bonan Chen, Yue Song, Yujuan Zhan, Shikun Zhou, Junzi Ke, Alvin H K Cheung

Cancer Lett· September 2022

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STK3 promotes gastric carcinogenesis by activating Ras-MAPK mediated cell cycle progression and serves as an independent prognostic biomarker.
Bonan Chen, Wai Nok Chan, Chun Wai Mui, Xiaoli Liu, Jinglin Zhang, Alvin H K Cheung

Mol Cancer· November 2021

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Hypoechoic liver in fetuses with trisomy 21.
Puspa Marlinda Omar, Wan Teng Lim, Yuen Ha Ting, Terence T Lao, Kwok Ming Law, Alvin Ho Kwan Cheung

J Matern Fetal Neonatal Med· October 2019

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FGF18, a prominent player in FGF signaling, promotes gastric tumorigenesis through autocrine manner and is negatively regulated by miR-590-5p.
Jinglin Zhang, Yuhang Zhou, Tingting Huang, Feng Wu, Yi Pan, Alvin H K Cheung

Oncogene· January 2019

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SRGAP1, a crucial target of miR-340 and miR-124, functions as a potential oncogene in gastric tumorigenesis.
Tingting Huang, Yuhang Zhou, Jinglin Zhang, Chi Chun Wong, Weilin Li, Alvin H K Cheung

Oncogene· March 2018

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miR-375 is involved in Hippo pathway by targeting YAP1/TEAD4-CTGF axis in gastric carcinogenesis.
Wei Kang, Tingting Huang, Yuhang Zhou, Jinglin Zhang, Raymond W M Lung, Alvin H K Cheung

Cell Death Dis· January 2018

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Preclinical analysis of the anti-tumor and anti-metastatic effects of Raf265 on colon cancer cells and CD26(+) cancer stem cells in colorectal carcinoma.
Ariel K M Chow, Nathan S M Cheng, Colin S C Lam, Lui Ng, Sunny K M Wong, Alvin H K Cheung

Mol Cancer· April 2015

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