Publications by authors named "Alwin D Huitema"

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Prolonged in-use physicochemical and biological stability of nivolumab and pembrolizumab diluted in saline infusion bags and in partially used medication vials.
A Hedvig Arnamo, Dick Pluim, Alwin Dr Huitema, Bart Aw Jacobs, Jos H Beijnen

J Oncol Pharm Pract· December 2025

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Improved survival with model-based dosing of antithymocyte globulin in pediatric hematopoietic cell transplantation.
Rick Admiraal, Stefan Nierkens, Marc B Bierings, Mirjam E Belderbos, Alwin D Huitema

Blood Adv· May 2025

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Redispensing of expensive oral anticancer medicines: A practical application.
Kübra Akgöl, Lisanne N van Merendonk, Hannerieke J Barkman, Dorieke Em van Balen, Hester L van den Hoek, Alwin Dr Huitema

J Oncol Pharm Pract· April 2024

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An easy, fast, and efficient assay for the quantification of peptide Hepcidin-25 in serum and plasma with LC-MS/MS.
Arjen M Punt, Joëlle C Wieman, Kim Cm van der Elst, Alwin Dr Huitema, Eef Gwm Lentjes

Ann Clin Biochem· September 2022

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Bottom-up sample preparation for the LC-MS/MS quantification of anti-cancer monoclonal antibodies in bio matrices.
Karen Am de Jong, Suse J van Breugel, Michel Jx Hillebrand, Hilde Rosing, Alwin Dr Huitema

Bioanalysis· October 2020

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Use of leftovers of monoclonal antibody products after partial extraction - A microbiological safety study.
A Hedvig Arnamo, Alwin Dr Huitema, Jos H Beijnen, Bastiaan Nuijen

J Oncol Pharm Pract· March 2020

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Treatment of Peritoneal Dissemination in Stomach Cancer Patients With Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC): Rationale and Design of the PERISCOPE Study.
Rosa T van der Kaaij, Hidde Jw Braam, Henk Boot, Maartje Los, Annemieke Cats, Alwin Dr Huitema

JMIR Res Protoc· July 2017

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Standard Clinical Protocol for Bidirectional Hyperthermic Intraperitoneal Chemotherapy (HIPEC): Systemic Leucovorin, 5-Fluorouracil, and Heated Intraperitoneal Oxaliplatin in a Chloride-Containing Carrier Solution.
Akash M Mehta, Alwin D R Huitema, Jacobus W A Burger, Alexandra R M Brandt-Kerkhof, Sander F van den Heuvel

Ann Surg Oncol· April 2017

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Imatinib Pharmacokinetics in a Large Observational Cohort of Gastrointestinal Stromal Tumour Patients.
Sheima Farag, Remy B Verheijen, J Martijn Kerst, Annemiek Cats, Alwin D R Huitema

Clin Pharmacokinet· March 2017

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Development of a Pharmacokinetic Model to Describe the Complex Pharmacokinetics of Pazopanib in Cancer Patients.
Huixin Yu, Nielka van Erp, Sander Bins, Ron H J Mathijssen, Jan H M Schellens, Alwin D R Huitema

Clin Pharmacokinet· March 2017

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Clinical pharmacokinetics of an amorphous solid dispersion tablet of elacridar.
Emilia Sawicki, Remy B Verheijen, Alwin D R Huitema, Olaf van Tellingen, Jan H M Schellens

Drug Deliv Transl Res· February 2017

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Individualized Pazopanib Dosing: A Prospective Feasibility Study in Cancer Patients.
Remy B Verheijen, Sander Bins, Ron H J Mathijssen, Martijn P Lolkema, Leni van Doorn, Alwin D R Huitema

Clin Cancer Res· December 2016

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Quantification of 11 Therapeutic Kinase Inhibitors in Human Plasma for Therapeutic Drug Monitoring Using Liquid Chromatography Coupled With Tandem Mass Spectrometry.
Maikel Herbrink, Niels de Vries, Hilde Rosing, Alwin D R Huitema, Bastiaan Nuijen

Ther Drug Monit· December 2016

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Individualized Pazopanib Dosing-Response.
Remy B Verheijen, Alwin D R Huitema, Neeltje Steeghs

Clin Cancer Res· December 2016

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A Semi-Physiological Population Model to Quantify the Effect of Hematocrit on Everolimus Pharmacokinetics and Pharmacodynamics in Cancer Patients.
Nielka P van Erp, Carla M van Herpen, Djoeke de Wit, Annelieke Willemsen, David M Burger, Alwin D R Huitema

Clin Pharmacokinet· November 2016

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The Use of Dried Blood Spots for Pharmacokinetic Monitoring of Vemurafenib Treatment in Melanoma Patients.
Cynthia M Nijenhuis, Alwin D R Huitema, Serena Marchetti, Christian Blank, John B A G Haanen

J Clin Pharmacol· October 2016

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Pharmacokinetics and excretion of (14)C-omacetaxine in patients with advanced solid tumors.
Cynthia M Nijenhuis, Edward Hellriegel, Jos H Beijnen, Diane Hershock, Alwin D R Huitema

Invest New Drugs· October 2016

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Development and clinical validation of an LC-MS/MS method for the quantification of pazopanib in DBS.
Remy B Verheijen, Sander Bins, Bas Thijssen, Hilde Rosing, Lianda Nan, Alwin D R Huitema

Bioanalysis· September 2016

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Pronounced between-subject and circadian variability in thymidylate synthase and dihydropyrimidine dehydrogenase enzyme activity in human volunteers.
Bart A W Jacobs, Maarten J Deenen, Dick Pluim, J G Coen van Hasselt, Martin D Krähenbühl, Alwin D R Huitema

Br J Clin Pharmacol· September 2016

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Cytosine arabinoside and daunorubicin induction therapy in a patient with acute myeloid leukemia on chronic hemodialysis.
Eilon Krashin, Osnat J Dolberg, Ilana Hellmann, Alwin D R Huitema, Hilde Rosing

Anticancer Drugs· September 2016

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A phase 0 clinical trial of novel candidate extended-release formulations of capecitabine.
Bart A W Jacobs, Jelte Meulenaar, Hilde Rosing, Dick Pluim, Matthijs M Tibben, Alwin D R Huitema

Cancer Chemother Pharmacol· June 2016

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Exploring the intracellular pharmacokinetics of the 5-fluorouracil nucleotides during capecitabine treatment.
Ellen J B Derissen, Bart A W Jacobs, Alwin D R Huitema, Hilde Rosing, Jan H M Schellens

Br J Clin Pharmacol· May 2016

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Proton Pump Inhibitor Prophylaxis After Gastric Bypass Does Not Cause Hypomagnesemia.
Thomas C C Boerlage, Charlotte L E van Hees, Alwin D R Huitema, Fanny N Lauw

Obes Surg· March 2016

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Crizotinib-induced fatal fulminant liver failure.
Robin M J M van Geel, Jeroen J M A Hendrikx, Jelmer E Vahl, Monique E van Leerdam, Daan van den Broek, Alwin D R Huitema

Lung Cancer· March 2016

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Pharmacokinetics of Selected Anticancer Drugs in Elderly Cancer Patients: Focus on Breast Cancer.
Marie-Rose B S Crombag, Markus Joerger, Beat Thürlimann, Jan H M Schellens, Jos H Beijnen, Alwin D R Huitema

Cancers (Basel)· January 2016

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