Publications by authors named "Alyson Smith"

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Targeted delivery of a potent STING agonist payload via an antibody drug conjugate drives robust antitumor activity in preclinical models.
David R Gruber, Elizabeth J Cummins, Weiping Zeng, Michelle Ulrich, Kaleb Smith, Alyson Smith

Mol Cancer Ther· October 2025

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Systematic Evaluation of Regiochemistry and Lipidation of Aryl Trehalose Mincle Agonists.
Asia Marie S Riel, Viktoria Rungelrath, Tamer A Elwaie, Omer K Rasheed, Linda Hicks, Mira Smith, Alyson J Smith

Int J Mol Sci· September 2024

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Nonfucosylation of an anti-TIGIT antibody enhances FcγR engagement, driving innate immune activation and antitumor activity.
Alyson J Smith, Robert E Thurman, Weiping Zeng, Bryan Grogan, Sasha Lucas

Front Immunol· December 2023

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SGN-B7H4V, an investigational vedotin ADC directed to the immune checkpoint ligand B7-H4, shows promising activity in preclinical models.
Elizabeth Gray, Michelle Ulrich, Angela Epp, Patrick Younan, Disha Sahetya, Alyson J Smith

J Immunother Cancer· October 2023

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Development of a TLR7/8 agonist adjuvant formulation to overcome early life hyporesponsiveness to DTaP vaccination.
David J Dowling, Soumik Barman, Alyson J Smith, Francesco Borriello, Danielle Chaney

Sci Rep· October 2022

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Telehealth-Based Delivery of Medication-Assisted Treatment for Opioid Use Disorder: a Critical Review of Recent Developments.
Hossam Mahmoud, Hady Naal, Emile Whaibeh, Alyson Smith

Curr Psychiatry Rep· September 2022

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High-content analysis and Kinetic Image Cytometry identify toxicity and epigenetic effects of HIV antiretrovirals on human iPSC-neurons and primary neural precursor cells.
Alyson S Smith, Soneela Ankam, Chen Farhy, Lorenzo Fiengo, Ranor C B Basa

J Pharmacol Toxicol Methods· March 2022

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Species-Specific Structural Requirements of Alpha-Branched Trehalose Diester Mincle Agonists.
Alyson J Smith, Shannon M Miller, Cassandra Buhl, Robert Child, Margaret Whitacre

Front Immunol· July 2020

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What is causing this patient's severe pruritus?
Emily A Probst, Alyson L Smith, John D Abad

JAAPA· June 2020

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Non-uniform distribution of myosin-mediated forces governs red blood cell membrane curvature through tension modulation.
Haleh Alimohamadi, Alyson S Smith, Roberta B Nowak, Velia M Fowler, Padmini Rangamani

PLoS Comput Biol· May 2020

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Aryl Trehalose Derivatives as Vaccine Adjuvants for .
Kendal T Ryter, George Ettenger, Omer K Rasheed, Cassandra Buhl, Robert Child, Alyson J Smith

J Med Chem· January 2020

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MYH9-related disease mutations cause abnormal red blood cell morphology through increased myosin-actin binding at the membrane.
Alyson S Smith, Kasturi Pal, Roberta B Nowak, Anastasiya Demenko, Carlo Zaninetti

Am J Hematol· June 2019

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Clostridium difficile infection in pregnant and postpartum women in 2 hospitals and a review of literature.
Manjula Meda, Nilangi Virgincar, Victoria Gentry, Amanda Walker, Neil Macdonald, Alyson Smith

Am J Infect Control· January 2019

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High-Resolution Fluorescence Microscope Imaging of Erythroblast Structure.
Alyson S Smith, Roberta B Nowak, Velia M Fowler

Methods Mol Biol· June 2018

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Myosin IIA interacts with the spectrin-actin membrane skeleton to control red blood cell membrane curvature and deformability.
Alyson S Smith, Roberta B Nowak, Sitong Zhou, Michael Giannetto, David S Gokhin

Proc Natl Acad Sci U S A· May 2018

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Immunoregulatory Activity of the Natural Product Laminarin Varies Widely as a Result of Its Physical Properties.
Alyson J Smith, Bridget Graves, Robert Child, Peter J Rice, Zuchao Ma

J Immunol· January 2018

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Quantification of Etoposide Hypersensitivity: A Sensitive, Functional Method for Assessing Pluripotent Stem Cell Quality.
Frank J Secreto, Xing Li, Alyson J Smith, Elizabeth S Bruinsma, Ester Perales-Clemente

Stem Cells Transl Med· October 2017

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Evaluation of novel synthetic TLR7/8 agonists as vaccine adjuvants.
Alyson J Smith, Yufeng Li, Hélène G Bazin, Julien R St-Jean, Daniel Larocque

Vaccine· August 2016

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Integration of Genomic and Other Epidemiologic Data to Investigate and Control a Cross-Institutional Outbreak of Streptococcus pyogenes.
Victoria J Chalker, Alyson Smith, Ali Al-Shahib, Stella Botchway, Emily Macdonald

Emerg Infect Dis· June 2016

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Strengthening health professions regulation in Cambodia: a rapid assessment.
David Clarke, Jan Duke, Tana Wuliji, Alyson Smith, Keat Phuong

Hum Resour Health· March 2016

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Two developmentally temporal quantitative trait loci underlie convergent evolution of increased branchial bone length in sticklebacks.
Priscilla A Erickson, Andrew M Glazer, Phillip A Cleves, Alyson S Smith, Craig T Miller

Proc Biol Sci· August 2014

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Is cardiac MRI an effective test for arrhythmogenic right ventricular cardiomyopathy diagnosis?
Santhi Chellamuthu, Alyson M Smith, Steven M Thomas, Catherine Hill, Peter W G Brown

World J Cardiol· July 2014

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A cause of a murmur: an internal mammary arterio-venous fistula.
Alyson Mary Smith, Abdallah Al-Mohammad, Peter William Gordon Brown

Eur J Cardiothorac Surg· March 2014

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Apoptotic susceptibility to DNA damage of pluripotent stem cells facilitates pharmacologic purging of teratoma risk.
Alyson J Smith, Natalie G Nelson, Saji Oommen, Katherine A Hartjes, Clifford D Folmes

Stem Cells Transl Med· October 2012

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Bak Conformational Changes Induced by Ligand Binding: Insight into BH3 Domain Binding and Bak Homo-Oligomerization.
Yuan-Ping Pang, Haiming Dai, Alyson Smith, X Wei Meng, Paula A Schneider

Sci Rep· September 2012

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