Publications by authors named "Alyssa D Gregory"

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Interpretable machine learning uncovers epithelial transcriptional rewiring and a role for Gelsolin in COPD.
Justin Sui, Hanxi Xiao, Ugonna Mbaekwe, Nai-Chun Ting, Kaley Murday, Alyssa D Gregory

JCI Insight· November 2024

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Extracellular Release of Mitochondrial DNA: Triggered by Cigarette Smoke and Detected in COPD.
Luca Giordano, Alyssa D Gregory, Mireia Pérez Verdaguer, Sarah A Ware, Hayley Harvey

Cells· January 2022

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USP13 Deficiency Aggravates Cigarette-smoke-induced Alveolar Space Enlargement.
Alyssa D Gregory, Kevin C Tran, Arya S Tamaskar, Jianxin Wei, Jing Zhao

Cell Biochem Biophys· September 2021

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Alveolar Macrophages Inherently Express Programmed Death-1 Ligand 1 for Optimal Protective Immunity and Tolerance.
Fan Sun, Liwen Li, Yadong Xiao, Alyssa D Gregory, Steven D Shapiro

J Immunol· July 2021

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RIP3-dependent necroptosis contributes to the pathogenesis of chronic obstructive pulmonary disease.
Dongshi Chen, Alyssa D Gregory, Xiaoyun Li, Jianxin Wei, Christine L Burton, Gregory Gibson

JCI Insight· June 2021

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Toll-Interacting Protein in Pulmonary Diseases. Abiding by the Goldilocks Principle.
Xiaoyun Li, Gillian C Goobie, Alyssa D Gregory, Daniel J Kass, Yingze Zhang

Am J Respir Cell Mol Biol· May 2021

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Single cell RNA sequencing identifies IGFBP5 and QKI as ciliated epithelial cell genes associated with severe COPD.
Xiuying Li, Guillaume Noell, Tracy Tabib, Alyssa D Gregory, Humberto E Trejo Bittar

Respir Res· April 2021

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PDLIM2 repression by ROS in alveolar macrophages promotes lung tumorigenesis.
Liwen Li, Fan Sun, Lei Han, Xujie Liu, Yadong Xiao, Alyssa D Gregory

JCI Insight· March 2021

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Adenine nucleotide translocase regulates airway epithelial metabolism, surface hydration and ciliary function.
Corrine R Kliment, Jennifer M K Nguyen, Mary Jane Kaltreider, YaWen Lu, Steven M Claypool, Alyssa D Gregory

J Cell Sci· February 2021

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Dual but not single PD-1 or TIM-3 blockade enhances oncolytic virotherapy in refractory lung cancer.
Fan Sun, Zong Sheng Guo, Alyssa D Gregory, Steven D Shapiro, Gutian Xiao

J Immunother Cancer· May 2020

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FSTL-1 Attenuation Causes Spontaneous Smoke-Resistant Pulmonary Emphysema.
Matthew Henkel, Jessica Partyka, Alyssa D Gregory, Erick Forno, Michael H Cho

Am J Respir Crit Care Med· April 2020

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Variable Susceptibility to Cigarette Smoke-Induced Emphysema in 34 Inbred Strains of Mice Implicates Abi3bp in Emphysema Susceptibility.
Josiah E Radder, Alyssa D Gregory, Adriana S Leme, Michael H Cho, Yanxia Chu

Am J Respir Cell Mol Biol· September 2017

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Macrophage Elastase Induces TRAIL-mediated Tumor Cell Death through Its Carboxy-Terminal Domain.
Nadine Dandachi, Neil J Kelly, John P Wood, Christine L Burton, Josiah E Radder, Alyssa D Gregory

Am J Respir Crit Care Med· August 2017

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Extreme Trait Whole-Genome Sequencing Identifies PTPRO as a Novel Candidate Gene in Emphysema with Severe Airflow Obstruction.
Josiah E Radder, Yingze Zhang, Alyssa D Gregory, Shibing Yu, Neil J Kelly

Am J Respir Crit Care Med· July 2017

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Mouse Genome-Wide Association Study of Preclinical Group II Pulmonary Hypertension Identifies Epidermal Growth Factor Receptor.
Neil J Kelly, Josiah E Radder, Jeffrey J Baust, Christine L Burton, Yen-Chun Lai, Alyssa D Gregory

Am J Respir Cell Mol Biol· April 2017

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Cigarette smoke destabilizes NLRP3 protein by promoting its ubiquitination.
SeungHye Han, Jacob A Jerome, Alyssa D Gregory, Rama K Mallampalli

Respir Res· January 2017

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Cost of surviving sepsis: a novel model of recovery from sepsis in Drosophila melanogaster.
Ata Murat Kaynar, Veli Bakalov, Silvia Martinez Laverde, Amélie I F Cambriel, Byoung-Hoon Lee, Alyssa D Gregory

Intensive Care Med Exp· December 2016

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Automated Measurement of Blood Vessels in Tissues from Microscopy Images.
Neil J Kelly, Nadine Dandachi, Dmitry A Goncharov, Andressa Z Pena, Josiah E Radder, Alyssa D Gregory

Curr Protoc Cytom· October 2016

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Authors' response.
A Murat Kaynar, Alyssa D Gregory, Steven D Shapiro, Derek C Angus

Crit Care· September 2015

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Neutrophil elastase promotes myofibroblast differentiation in lung fibrosis.
Alyssa D Gregory, Corrine R Kliment, Heather E Metz, Kyoung-Hee Kim, Julia Kargl

J Leukoc Biol· August 2015

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Effects of intra-abdominal sepsis on atherosclerosis in mice.
Ata Murat Kaynar, Sachin Yende, Lin Zhu, Daniel R Frederick, Robin Chambers, Alyssa D Gregory

Crit Care· September 2014

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Clathrin pit-mediated endocytosis of neutrophil elastase and cathepsin G by cancer cells.
Alyssa D Gregory, Pamela Hale, David H Perlmutter, A McGarry Houghton

J Biol Chem· October 2012

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Tumor-associated neutrophils: new targets for cancer therapy.
Alyssa D Gregory, A McGarry Houghton

Cancer Res· April 2011

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Systemic levels of G-CSF and interleukin-6 determine the angiogenic potential of bone marrow resident monocytes.
Alyssa D Gregory, Benjamin J Capoccia, Jill R Woloszynek, Daniel C Link

J Leukoc Biol· July 2010

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Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth.
A McGarry Houghton, Danuta M Rzymkiewicz, Hongbin Ji, Alyssa D Gregory, Eduardo E Egea

Nat Med· February 2010

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