Publications by authors named "Alyssa Neill"

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Characterization of the bispecific VHH antibody gefurulimab (ALXN1720) targeting complement component 5, and designed for low volume subcutaneous administration.
Siddharth Jindal, Dennis Vestergaard Pedersen, Nimish Gera, Julian Chandler, Rekha Patel, Alyssa Neill

Mol Immunol· January 2024

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Analytical comparability study of recombinant monoclonal antibody therapeutics.
Alexandre Ambrogelly, Stephen Gozo, Amit Katiyar, Shara Dellatore, Yune Kune, Alyssa Neill

MAbs· August 2019

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Forced degradation of recombinant monoclonal antibodies: A practical guide.
Christine Nowak, Jason K Cheung, Shara M Dellatore, Amit Katiyar, Ram Bhat, Alyssa Neill

MAbs· July 2018

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Characterization of recombinant monoclonal antibody variants detected by hydrophobic interaction chromatography and imaged capillary isoelectric focusing electrophoresis.
Cory King, Rekha Patel, Gomathinayagam Ponniah, Christine Nowak, Alyssa Neill

J Chromatogr B Analyt Technol Biomed Life Sci· May 2018

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Impact of IgG Fc-Oligosaccharides on Recombinant Monoclonal Antibody Structure, Stability, Safety, and Efficacy.
Hongcheng Liu, Christine Nowak, Bruce Andrien, Mei Shao, Gomathinayagam Ponniah, Alyssa Neill

Biotechnol Prog· September 2017

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Characterization of succinimide stability during trypsin digestion for LC-MS analysis.
Christine Nowak, Gomathinayagam Ponniah, Alyssa Neill, Hongcheng Liu

Anal Biochem· June 2017

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A high density CHO-S transient transfection system: Comparison of ExpiCHO and Expi293.
Nina K Jain, Susan Barkowski-Clark, Richard Altman, Krista Johnson, Fang Sun, Alyssa Neill

Protein Expr Purif· June 2017

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Characterization of charge variants of a monoclonal antibody using weak anion exchange chromatography at subunit levels.
Gomathinayagam Ponniah, Christine Nowak, Alyssa Neill, Hongcheng Liu

Anal Biochem· March 2017

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Impact of cell culture on recombinant monoclonal antibody product heterogeneity.
Hongcheng Liu, Christine Nowak, Mei Shao, Gomathinayagam Ponniah, Alyssa Neill

Biotechnol Prog· September 2016

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Structural Basis for Eculizumab-Mediated Inhibition of the Complement Terminal Pathway.
Janus Asbjørn Schatz-Jakobsen, Yuchun Zhang, Krista Johnson, Alyssa Neill, Douglas Sheridan

J Immunol· July 2016

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Liquid chromatography-fluorescence and liquid chromatography-mass spectrometry detection of tryptophan degradation products of a recombinant monoclonal antibody.
Christine Nowak, Gomathinayagam Ponniah, Guilong Cheng, Adriana Kita, Alyssa Neill

Anal Biochem· March 2016

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A conventional procedure to reduce Asn deamidation artifacts during trypsin peptide mapping.
Yekaterina Kori, Rekha Patel, Alyssa Neill, Hongcheng Liu

J Chromatogr B Analyt Technol Biomed Life Sci· January 2016

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Characterization of the acidic species of a monoclonal antibody using weak cation exchange chromatography and LC-MS.
Gomathinayagam Ponniah, Adriana Kita, Christine Nowak, Alyssa Neill, Yekaterina Kori

Anal Chem· September 2015

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In vitro and in vivo modifications of recombinant and human IgG antibodies.
Hongcheng Liu, Gomathinayagam Ponniah, Hui-Min Zhang, Christine Nowak, Alyssa Neill

MAbs· August 2015

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IgG subclass specificity to C1q determined by surface plasmon resonance using Protein L capture technique.
Rekha Patel, Alyssa Neill, Hongcheng Liu, Bruce Andrien

Anal Biochem· June 2015

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Characterization of Recombinant Monoclonal Antibody Charge Variants Using OFFGEL Fractionation, Weak Anion Exchange Chromatography, and Mass Spectrometry.
Alyssa Neill, Christine Nowak, Rekha Patel, Gomathinayagam Ponniah, Nidia Gonzalez

Anal Chem· June 2015

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Identification and comparative quantitation of glycation by stable isotope labeling and LC-MS.
Hongcheng Liu, Gomathinayagam Ponniah, Alyssa Neill, Rekha Patel, Bruce Andrien

J Chromatogr B Analyt Technol Biomed Life Sci· May 2014

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Accurate determination of protein methionine oxidation by stable isotope labeling and LC-MS analysis.
Hongcheng Liu, Gomathinayagam Ponniah, Alyssa Neill, Rekha Patel, Bruce Andrien

Anal Chem· December 2013

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