Publications by authors named "Amanda B Hummon"

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Quantitative Top-Down Proteomics Reveals Significant Differences in Histone Proteoforms Between Metastatic and Nonmetastatic Colorectal Cancer Cells.
Fei Fang, Brian Fries, Zhige Wang, Xiaowen Liu, Amanda B Hummon

Proteomics· December 2025

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Discovery and targeted Mass spectrometry-based proteomics of Ovarian cancer.
Nicole E Platzer, Amanda B Hummon

Expert Rev Proteomics· December 2025

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Longitudinal Proteomic Changes in HCT 116 Colon Cancer Spheroids During Growth.
Catherine B Whitney, Nicole C Beller, Brian D Fries, Arbil Lopez, Amanda B Hummon

J Proteome Res· August 2025

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MALDI Imaging and Spatial SILAC Proteomics of Three-Dimensional Multicellular Spheroids Dynamically Dosed with Doxorubicin-Encapsulating Liposomes.
Arbil Lopez, Joseph H Holbrook, Amanda B Hummon

Anal Chem· June 2025

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Mass Spectrometry-Based Applications of Spheroids in Cancer Biology.
Brian D Fries, Amanda B Hummon

Annu Rev Anal Chem (Palo Alto Calif)· May 2025

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Multi-Omic Evaluation of PLK1 Inhibitor-Onvansertib-In Colorectal Cancer Spheroids.
Brian D Fries, Emily R Sekera, Joseph H Holbrook, Amanda B Hummon

J Mass Spectrom· May 2025

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Light-Reactive Norharmane Derivatization of Lipid Isomers by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry.
Thomas R Fredriksen, Joseph H Holbrook, Lorena Rosas, Quetzalli D Angeles-Lopez, Ana L Mora, Amanda B Hummon

Anal Chem· March 2025

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Single Cell MALDI-MSI Analysis of Lipids and Proteins within a Replicative Senescence Fibroblast Model.
Emily R Sekera, Lorena Rosas, Joseph H Holbrook, Quetzalli D Angeles-Lopez, Timur Khaliullin, Amanda B Hummon

J Am Soc Mass Spectrom· December 2024

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Single Cell MALDI-MSI Analysis of Lipids and Proteins within a Replicative Senescence Fibroblast Model.
Emily R Sekera, Lorena Rosas, Joseph H Holbrook, Quetzalli D Angeles-Lopez, Timur Khaliullin, Amanda B Hummon

bioRxiv· September 2024

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FAS Inhibited Proteomics and Phosphoproteomics Profiling of Colorectal Cancer Spheroids Shows Activation of Ferroptotic Death Mechanism.
Brian D Fries, Amanda B Hummon

J Proteome Res· September 2024

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Lipidomics Profiling Reveals Differential Alterations after FAS Inhibition in 3D Colon Cancer Cell Culture Models.
Brian D Fries, Fernando Tobias, Yijia Wang, Joseph H Holbrook, Amanda B Hummon

J Proteome Res· August 2024

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Gas-Phase Fractionation Data-Independent Acquisition Analysis of 3D Cocultured Spheroid Tumor Model Reveals Altered Translational Processes and Signaling Using Proteomics.
Ariana E Shannon, Claire E Boos, Brian C Searle, Amanda B Hummon

J Proteome Res· August 2024

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Tracking Drugs and Lipids: Quantitative Mass Spectrometry Imaging of Liposomal Doxorubicin Delivery and Bilayer Fate in Three-Dimensional Tumor Models.
Arbil Lopez, Joseph H Holbrook, Gabrielle E Kemper, Jessica K Lukowski, William T Andrews, Amanda B Hummon

Anal Chem· June 2024

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Mass Spectrometry Imaging and Histology for the Analysis of Budding Intestinal Organoids.
Emily R Sekera, Kubra B Akkaya-Colak, Arbil Lopez, Maria M Mihaylova, Amanda B Hummon

Anal Chem· March 2024

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Quantitative mass spectrometry imaging: therapeutics & biomolecules.
Joseph H Holbrook, Gabrielle E Kemper, Amanda B Hummon

Chem Commun (Camb)· February 2024

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Workflow for Evaluating Normalization Tools for Omics Data Using Supervised and Unsupervised Machine Learning.
Aleesa E Chua, Leah D Pfeifer, Emily R Sekera, Amanda B Hummon, Heather Desaire

J Am Soc Mass Spectrom· December 2023

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Crystalline Nanoparticles of Water-Soluble Covalent Basket Cages (CBCs) for Encapsulation of Anticancer Drugs.
Vageesha W Liyana Gunawardana, Carson Ward, Han Wang, Joseph H Holbrook, Emily R Sekera, Amanda B Hummon

Angew Chem Int Ed Engl· August 2023

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Evaluating the Pharmacokinetics and Pharmacodynamics of Chemotherapeutics within a Spatial SILAC-Labeled Spheroid Model System.
Nicole C Beller, Yijia Wang, Amanda B Hummon

Anal Chem· August 2023

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Targeting a xenobiotic transporter to ameliorate vincristine-induced sensory neuropathy.
Yang Li, Thomas Drabison, Mahesh Nepal, Richard H Ho, Alix F Leblanc, Amanda B Hummon

JCI Insight· July 2023

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Enhancement of Lipid Signals in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry with Ammonium Fluoride as a Matrix Additive.
Joseph H Holbrook, Emily R Sekera, Arbil Lopez, Brian D Fries, Fernando Tobias, Amanda B Hummon

Anal Chem· July 2023

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Quantification of Irinotecan in Single Spheroids Using Internal Standards by MALDI Mass Spectrometry Imaging.
Yijia Wang, Amanda B Hummon

Anal Chem· June 2023

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Development of Spheroid-FPOP: An In-Cell Protein Footprinting Method for 3D Tumor Spheroids.
Raquel L Shortt, Yijia Wang, Amanda B Hummon, Lisa M Jones

J Am Soc Mass Spectrom· March 2023

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Multi-glycomic analysis of spheroid glycocalyx differentiates 2- and 3-dimensional cell models.
Qingwen Zhou, Michael Russelle S Alvarez, Kemal Solakyildirim, Jennyfer Tena, Luster Mae N Serrano, Amanda B Hummon

Glycobiology· January 2023

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Deep top-down proteomics revealed significant proteoform-level differences between metastatic and nonmetastatic colorectal cancer cells.
Elijah N McCool, Tian Xu, Wenrong Chen, Nicole C Beller, Scott M Nolan, Amanda B Hummon

Sci Adv· December 2022

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Generation of Proteins with Free N-Terminal Cysteine by Aminopeptidases.
Jordan P Hempfling, Emily R Sekera, Amar Sarkar, Amanda B Hummon, Dehua Pei

J Am Chem Soc· November 2022

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