Publications by authors named "Amberley D Stephens"

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Local Ionic Conditions Modulate the Aggregation Propensity and Influence the Structural Polymorphism of α-Synuclein.
Maria Zacharopoulou, Neeleema Seetaloo, James Ross, Amberley D Stephens, Giuliana Fusco

J Am Chem Soc· April 2025

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Discovery of Therapeutic Antibodies Targeting Complex Multi-Spanning Membrane Proteins.
Amberley D Stephens, Trevor Wilkinson

BioDrugs· November 2024

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α-Synuclein fibril and synaptic vesicle interactions lead to vesicle destruction and increased lipid-associated fibril uptake into iPSC-derived neurons.
Amberley D Stephens, Ana Fernandez Villegas, Chyi Wei Chung, Oliver Vanderpoorten, Dorothea Pinotsi

Commun Biol· May 2023

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Decreased Water Mobility Contributes To Increased α-Synuclein Aggregation.
Amberley D Stephens, Johanna Kölbel, Rani Moons, Chyi Wei Chung, Michael T Ruggiero

Angew Chem Int Ed Engl· February 2023

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Decreased Water Mobility Contributes To Increased α-Synuclein Aggregation.
Amberley D Stephens, Johanna Kölbel, Rani Moons, Chyi Wei Chung, Michael T Ruggiero

Angew Chem Weinheim Bergstr Ger· February 2023

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Millisecond Hydrogen/Deuterium-Exchange Mass Spectrometry Approach to Correlate Local Structure and Aggregation in α-Synuclein.
Neeleema Seetaloo, Maria Zacharopoulou, Amberley D Stephens, Gabriele S Kaminski Schierle, Jonathan J Phillips

Anal Chem· December 2022

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Intracellular Aβ42 Aggregation Leads to Cellular Thermogenesis.
Chyi Wei Chung, Amberley D Stephens, Tasuku Konno, Edward Ward, Edward Avezov

J Am Chem Soc· June 2022

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Label-Free Characterization of Amyloids and Alpha-Synuclein Polymorphs by Exploiting Their Intrinsic Fluorescence Property.
Chyi Wei Chung, Amberley D Stephens, Edward Ward, Yuqing Feng, Molly Jo Davis

Anal Chem· April 2022

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Short hydrogen bonds enhance nonaromatic protein-related fluorescence.
Amberley D Stephens, Muhammad Nawaz Qaisrani, Michael T Ruggiero, Gonzalo Díaz Mirón, Uriel N Morzan

Proc Natl Acad Sci U S A· May 2021

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Purification of Recombinant α-synuclein: A Comparison of Commonly Used Protocols.
Amberley D Stephens, Dijana Matak-Vinkovic, Ana Fernandez-Villegas, Gabriele S Kaminski Schierle

Biochemistry· December 2020

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Fast Purification of Recombinant Monomeric Amyloid-β from and Amyloid-β-mCherry Aggregates from Mammalian Cells.
Amberley D Stephens, Meng Lu, Ana Fernandez-Villegas, Gabriele S Kaminski Schierle

ACS Chem Neurosci· October 2020

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Intramitochondrial proteostasis is directly coupled to α-synuclein and amyloid β1-42 pathologies.
Janin Lautenschläger, Sara Wagner-Valladolid, Amberley D Stephens, Ana Fernández-Villegas, Colin Hockings

J Biol Chem· July 2020

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Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity.
Amberley D Stephens, Maria Zacharopoulou, Rani Moons, Giuliana Fusco, Neeleema Seetaloo

Nat Commun· June 2020

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Observation of high-temperature macromolecular confinement in lyophilised protein formulations using terahertz spectroscopy.
Talia A Shmool, P J Woodhams, Markus Leutzsch, Amberley D Stephens, Mario U Gaimann

Int J Pharm X· December 2019

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Low energy optical excitations as an indicator of structural changes initiated at the termini of amyloid proteins.
Kwang Hyok Jong, Yavar T Azar, Luca Grisanti, Amberley D Stephens, Saul T E Jones

Phys Chem Chem Phys· November 2019

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Isolation and Imaging of His- and RFP-tagged Amyloid-like Proteins from by TEM and SIM.
Amberley D Stephens, Meng Lu, Gabriele S Kaminski Schierle

Bio Protoc· November 2019

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The role of water in amyloid aggregation kinetics.
Amberley D Stephens, Gabriele S Kaminski Schierle

Curr Opin Struct Biol· October 2019

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The Cellular Environment Affects Monomeric α-Synuclein Structure.
Amberley D Stephens, Maria Zacharopoulou, Gabriele S Kaminski Schierle

Trends Biochem Sci· May 2019

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Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in .
Chaolie Huang, Sara Wagner-Valladolid, Amberley D Stephens, Raimund Jung, Chetan Poudel

Elife· May 2019

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Different Structural Conformers of Monomeric α-Synuclein Identified after Lyophilizing and Freezing.
Amberley D Stephens, Nadezhda Nespovitaya, Maria Zacharopoulou, Clemens F Kaminski, Jonathan J Phillips

Anal Chem· June 2018

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C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction.
Janin Lautenschläger, Amberley D Stephens, Giuliana Fusco, Florian Ströhl, Nathan Curry

Nat Commun· February 2018

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Phylogeographic diversity and mosaicism of the integrative and conjugative elements.
Robin M Delahay, Nicola J Croxall, Amberley D Stephens

Mob DNA· January 2018

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Corrigendum: Structural basis of synaptic vesicle assembly promoted by α-synuclein.
Giuliana Fusco, Tillmann Pape, Amberley D Stephens, Pierre Mahou, Ana Rita Costa

Nat Commun· May 2017

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Structural basis of synaptic vesicle assembly promoted by α-synuclein.
Giuliana Fusco, Tillmann Pape, Amberley D Stephens, Pierre Mahou, Ana Rita Costa

Nat Commun· September 2016

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