Publications by authors named "Amit Mahindra"

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Lysine targeting covalent inhibitors of malarial kinase CLK3.
Skye B Brettell, Gillian Cann, Abbey Begen, Saumya Sharma, Amit Mahindra

RSC Med Chem· August 2025

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Design, synthesis, and applications of ring-functionalized histidines in peptide-based medicinal chemistry and drug discovery.
Komal Sharma, Krishna K Sharma, Amit Mahindra, Naina Sehra, Nitin Bagra

Med Res Rev· July 2023

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Investigating the Structure-Activity Relationship of 1,2,4-Triazine G-Protein-Coupled Receptor 84 (GPR84) Antagonists.
Amit Mahindra, Laura Jenkins, Sara Marsango, Mark Huggett, Margaret Huggett

J Med Chem· August 2022

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Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction.
Amit Mahindra, Gonzalo Tejeda, Mario Rossi, Omar Janha, Imogen Herbert

PLoS One· November 2021

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Stapled ACE2 peptidomimetics designed to target the SARS-CoV-2 spike protein do not prevent virus internalization.
Danielle C Morgan, Caroline Morris, Amit Mahindra, Connor M Blair, Gonzalo Tejeda

Pept Sci (Hoboken)· July 2021

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Development of Potent CLK3 Inhibitors Based on TCMDC-135051 as a New Class of Antimalarials.
Amit Mahindra, Omar Janha, Kopano Mapesa, Ana Sanchez-Azqueta, Mahmood M Alam

J Med Chem· September 2020

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Validation of the protein kinase CLK3 as a multistage cross-species malarial drug target.
Mahmood M Alam, Ana Sanchez-Azqueta, Omar Janha, Erika L Flannery, Amit Mahindra

Science· August 2019

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Synthesis of HDAC Substrate Peptidomimetic Inhibitors Using Fmoc Amino Acids Incorporating Zinc-Binding Groups.
Amit Mahindra, Christopher J Millard, Iona Black, Lewis J Archibald, John W R Schwabe

Org Lett· May 2019

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Lipopeptidomimetics derived from teixobactin have potent antibacterial activity against Staphylococcus aureus.
Georgina C Girt, Amit Mahindra, Zaaima J H Al Jabri, Megan De Ste Croix, Marco R Oggioni

Chem Commun (Camb)· March 2018

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Synthetically modified L-histidine-rich peptidomimetics exhibit potent activity against Cryptococcus neoformans.
Amit Mahindra, Nitin Bagra, Nishima Wangoo, Rohan Jain, Shabana I Khan

Bioorg Med Chem Lett· July 2014

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Regiocontrolled palladium-catalyzed and copper-mediated C-H bond functionalization of protected L-histidine.
Amit Mahindra, Rahul Jain

Org Biomol Chem· June 2014

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Synthesis and Antimicrobial Activities of His(2-aryl)-Arg and Trp-His(2-aryl) Classes of Dipeptidomimetics.
Amit Mahindra, Krishna K Sharma, Dinesh Rathore, Shabana I Khan, Melissa R Jacob

Medchemcomm· May 2014

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Discovery of Short Peptides Exhibiting High Potency against Cryptococcus neoformans.
Amit Mahindra, Nitin Bagra, Nishima Wangoo, Shabana I Khan, Melissa R Jacob

ACS Med Chem Lett· April 2014

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Palladium-catalyzed regioselective C-5 arylation of protected L-histidine: microwave-assisted C-H activation adjacent to donor arm.
Amit Mahindra, Nitin Bagra, Rahul Jain

J Org Chem· November 2013

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