Publications by authors named "Amit Modgil"

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Preclinical characterization of zuranolone (SAGE-217), a selective neuroactive steroid GABA receptor positive allosteric modulator.
Alison L Althaus, Michael A Ackley, Gabriel M Belfort, Steven M Gee, Jing Dai, Amit Modgil

Neuropharmacology· December 2020

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Nanotechnology: Revolutionizing the Science of Drug Delivery.
Mohini Mishra, Pramod Kumar, Jitendra Singh Rajawat, Ruchi Malik, Gitanjali Sharma, Amit Modgil

Curr Pharm Des· December 2019

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Metabotropic, but not allosteric, effects of neurosteroids on GABAergic inhibition depend on the phosphorylation of GABA receptors.
Manasa L Parakala, Yihui Zhang, Amit Modgil, Jayashree Chadchankar, Thuy N Vien

J Biol Chem· August 2019

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Neuroactive Steroids Reverse Tonic Inhibitory Deficits in Fragile X Syndrome Mouse Model.
Amit Modgil, Thuy N Vien, Michael A Ackley, James J Doherty, Stephen J Moss

Front Mol Neurosci· February 2019

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Developmental seizures and mortality result from reducing GABA receptor α2-subunit interaction with collybistin.
Rochelle M Hines, Hans Michael Maric, Dustin J Hines, Amit Modgil, Patrizia Panzanelli

Nat Commun· August 2018

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Genetic Deletion of the Clathrin Adaptor GGA3 Reduces Anxiety and Alters GABAergic Transmission.
Kendall R Walker, Amit Modgil, David Albrecht, Selene Lomoio, Philip G Haydon

PLoS One· July 2017

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Endogenous and synthetic neuroactive steroids evoke sustained increases in the efficacy of GABAergic inhibition via a protein kinase C-dependent mechanism.
Amit Modgil, Manasa L Parakala, Michael A Ackley, James J Doherty, Stephen J Moss

Neuropharmacology· February 2017

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Proteomic Characterization of Inhibitory Synapses Using a Novel pHluorin-tagged γ-Aminobutyric Acid Receptor, Type A (GABAA), α2 Subunit Knock-in Mouse.
Yasuko Nakamura, Danielle H Morrow, Amit Modgil, Deborah Huyghe, Tarek Z Deeb

J Biol Chem· June 2016

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The Role of Cell-Penetrating Peptide and Transferrin on Enhanced Delivery of Drug to Brain.
Gitanjali Sharma, Sushant Lakkadwala, Amit Modgil, Jagdish Singh

Int J Mol Sci· May 2016

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Compromising the phosphodependent regulation of the GABAAR β3 subunit reproduces the core phenotypes of autism spectrum disorders.
Thuy N Vien, Amit Modgil, Armen M Abramian, Rachel Jurd, Joshua Walker

Proc Natl Acad Sci U S A· December 2015

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Apelin-13 inhibits large-conductance Ca2+-activated K+ channels in cerebral artery smooth muscle cells via a PI3-kinase dependent mechanism.
Amit Modgil, Lirong Guo, Stephen T O'Rourke, Chengwen Sun

PLoS One· September 2014

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Maternal nutrient restriction during pregnancy impairs an endothelium-derived hyperpolarizing factor-like pathway in sheep fetal coronary arteries.
Praveen Shukla, Srinivas Ghatta, Nidhi Dubey, Caleb O Lemley, Mary Lynn Johnson, Amit Modgil

Am J Physiol Heart Circ Physiol· July 2014

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Influence of short-chain cell-penetrating peptides on transport of doxorubicin encapsulating receptor-targeted liposomes across brain endothelial barrier.
Gitanjali Sharma, Amit Modgil, Tiecheng Zhong, Chengwen Sun, Jagdish Singh

Pharm Res· May 2014

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Neurosteroids promote phosphorylation and membrane insertion of extrasynaptic GABAA receptors.
Armen M Abramian, Eydith Comenencia-Ortiz, Amit Modgil, Thuy N Vien, Yasuko Nakamura

Proc Natl Acad Sci U S A· May 2014

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Cell penetrating peptide tethered bi-ligand liposomes for delivery to brain in vivo: Biodistribution and transfection.
Gitanjali Sharma, Amit Modgil, Buddhadev Layek, Kanwardeep Arora, Chengwen Sun

J Control Release· April 2013

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Invertible micellar polymer assemblies for delivery of poorly water-soluble drugs.
Ivan Hevus, Amit Modgil, Justin Daniels, Ananiy Kohut, Chengwen Sun

Biomacromolecules· August 2012

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Grafting of cell-penetrating peptide to receptor-targeted liposomes improves their transfection efficiency and transport across blood-brain barrier model.
Gitanjali Sharma, Amit Modgil, Chengwen Sun, Jagdish Singh

J Pharm Sci· July 2012

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Angiotensin-(1-7) attenuates the chronotropic response to angiotensin II via stimulation of PTEN in the spontaneously hypertensive rat neurons.
Amit Modgil, Qi Zhang, Ajeeth Pingili, Neha Singh, Fanrong Yao

Am J Physiol Heart Circ Physiol· March 2012

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Pressor effect of apelin-13 in the rostral ventrolateral medulla: role of NAD(P)H oxidase-derived superoxide.
Fanrong Yao, Amit Modgil, Qi Zhang, Ajeeth Pingili, Neha Singh

J Pharmacol Exp Ther· February 2011

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