Publications by authors named "Amit Sabnis"

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manipulation of the protein homeostasis network in rhabdomyosarcoma.
Kristen Kwong, Yue Pan, Jacqueline Morales, Matthew Watson, David V Allegakoen, Amit J Sabnis

Oncotarget· August 2025

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Phase II Study of Ulixertinib in Children and Young Adults With Tumors Harboring Activating Mitogen-Activated Protein Kinase Pathway Alterations: APEC1621J of the National Cancer Institute-Children's Oncology Group Pediatric MATCH Trial.
Kieuhoa T Vo, Amit J Sabnis, P Mickey Williams, Sinchita Roy-Chowdhuri, David R Patton

JCO Precis Oncol· June 2024

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The essential chaperone DNAJC17 activates HSP70 to coordinate RNA splicing and G2-M progression.
David V Allegakoen, Kristen Kwong, Jacqueline Morales, Trever G Bivona, Amit J Sabnis

bioRxiv· October 2023

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Clinical Targeted Next-Generation Panel Sequencing Reveals Amplification Is a Poor Prognostic Factor in Osteosarcoma.
Amanda E Marinoff, Liam F Spurr, Christina Fong, Yvonne Y Li, Suzanne J Forrest, Amit J Sabnis

JCO Precis Oncol· March 2023

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GATOR2-dependent mTORC1 activity is a therapeutic vulnerability in FOXO1 fusion-positive rhabdomyosarcoma.
Jacqueline Morales, David V Allegakoen, José A Garcia, Kristen Kwong, Pushpendra K Sahu, Amit J Sabnis

JCI Insight· December 2022

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Rare FGFR Oncogenic Alterations in Sequenced Pediatric Solid and Brain Tumors Suggest FGFR Is a Relevant Molecular Target in Childhood Cancer.
Lorena Lazo De La Vega, Hannah Comeau, Sarah Sallan, Alyaa Al-Ibraheemi, Hersh Gupta, Amit J Sabnis

JCO Precis Oncol· November 2022

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Entrectinib in children and young adults with solid or primary CNS tumors harboring NTRK, ROS1, or ALK aberrations (STARTRK-NG).
Ami V Desai, Giles W Robinson, Karen Gauvain, Ellen M Basu, Margaret E Macy, Amit J Sabnis

Neuro Oncol· October 2022

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Molecular profiling identifies targeted therapy opportunities in pediatric solid cancer.
Alanna J Church, Laura B Corson, Pei-Chi Kao, Alma Imamovic-Tuco, Deirdre Reidy, Amit J Sabnis

Nat Med· August 2022

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Clinical characteristics and outcomes of infants compared with children diagnosed with rhabdomyosarcoma: Analysis of surveillance, epidemiology and end results data from 2000 to 2016.
Hannah D Rees, Nancy K Hills, Amit J Sabnis, Asmin B Tulpule, Tom K Shimotake

Cancer Rep (Hoboken)· May 2022

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Germline Sequencing Improves Tumor-Only Sequencing Interpretation in a Precision Genomic Study of Patients With Pediatric Solid Tumor.
Jaclyn Schienda, Alanna J Church, Laura B Corson, Brennan Decker, Catherine M Clinton, Amit J Sabnis

JCO Precis Oncol· March 2022

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Germline MUTYH Mutation in a Pediatric Cancer Survivor Developing a Secondary Malignancy.
Vincent Lavergne, Amit Sabnis, Asmin Tupule, Philip R Davidson, Cassie Kline

J Pediatr Hematol Oncol· October 2020

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Use of three-dimensional printing and intraoperative navigation in the surgical resection of metastatic acetabular osteosarcoma.
Julia C Heunis, Jonathan W Cheah, Amit J Sabnis, Rosanna L Wustrack

BMJ Case Rep· September 2019

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Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers.
Nilanjana Chatterjee, Evangelos Pazarentzos, Manasi K Mayekar, Philippe Gui, David V Allegakoen, Amit J Sabnis

Cell Rep· August 2019

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Principles of Resistance to Targeted Cancer Therapy: Lessons from Basic and Translational Cancer Biology.
Amit J Sabnis, Trever G Bivona

Trends Mol Med· March 2019

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Development and validation of a robust multiplex serological assay to quantify antibodies specific to pertussis antigens.
Gowrisankar Rajam, George Carlone, Ellie Kim, Jin Choi, Simon Paulos, Amit Sabnis

Biologicals· January 2019

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EWSR1-NFATC2 gene fusion in a soft tissue tumor with epithelioid round cell morphology and abundant stroma: a case report and review of the literature.
Jarish N Cohen, Amit J Sabnis, Gregor Krings, Soo-Jin Cho, Andrew E Horvai

Hum Pathol· November 2018

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Compensatory increases of select proteostasis networks after Hsp70 inhibition in cancer cells.
Sara Sannino, Christopher J Guerriero, Amit J Sabnis, Donna Beer Stolz, Callen T Wallace

J Cell Sci· September 2018

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Reducing Second Gram-Negative Antibiotic Therapy on Pediatric Oncology and Hematopoietic Stem Cell Transplantation Services.
Rachel L Wattier, Emily R Levy, Amit J Sabnis, Christopher C Dvorak, Andrew D Auerbach

Infect Control Hosp Epidemiol· September 2017

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HSP70 dependence in rhabdomyosarcoma: Seed or soil?
Amit J Sabnis, Trever G Bivona

Cell Cycle· January 2017

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Validation of high throughput screening of human sera for detection of anti-PA IgG by Enzyme-Linked Immunosorbent Assay (ELISA) as an emergency response to an anthrax incident.
Vera A Semenova, Evelene Steward-Clark, Panagiotis Maniatis, Monica Epperson, Amit Sabnis

Biologicals· January 2017

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Effect of Anti-IL-15 Administration on T Cell and NK Cell Homeostasis in Rhesus Macaques.
Maren Q DeGottardi, Afam A Okoye, Mukta Vaidya, Aarthi Talla, Audrie L Konfe, Amit Sabnis

J Immunol· August 2016

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Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma.
Amit J Sabnis, Christopher J Guerriero, Victor Olivas, Anin Sayana, Jonathan Shue

Proc Natl Acad Sci U S A· August 2016

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RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer.
Gorjan Hrustanovic, Victor Olivas, Evangelos Pazarentzos, Asmin Tulpule, Saurabh Asthana, Amit Sabnis

Nat Med· September 2015

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The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies.
Luping Lin, Amit J Sabnis, Elton Chan, Victor Olivas, Lindsay Cade

Nat Genet· March 2015

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Activating mutations cluster in the "molecular brake" regions of protein kinases and do not associate with conserved or catalytic residues.
Miguel A Molina-Vila, Nuria Nabau-Moretó, Cristian Tornador, Amit J Sabnis, Rafael Rosell

Hum Mutat· March 2014

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