Publications by authors named "Amy Hacker"

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The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines.
Allison Pledgie-Tracy, Madhavi Billam, Amy Hacker, Michele D Sobolewski, Patrick M Woster

Cancer Chemother Pharmacol· May 2010

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In vitro and in vivo effects of the conformationally restricted polyamine analogue CGC-11047 on small cell and non-small cell lung cancer cells.
Amy Hacker, Laurence J Marton, Michelle Sobolewski, Robert A Casero

Cancer Chemother Pharmacol· December 2008

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Microbial community composition in soils of Northern Victoria Land, Antarctica.
Thomas D Niederberger, Ian R McDonald, Amy L Hacker, Rochelle M Soo, John E Barrett

Environ Microbiol· July 2008

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Nuclear localization of human spermine oxidase isoforms - possible implications in drug response and disease etiology.
Tracy Murray-Stewart, Yanlin Wang, Andrew Goodwin, Amy Hacker, Alan Meeker

FEBS J· June 2008

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Tumor necrosis factor alpha induces spermidine/spermine N1-acetyltransferase through nuclear factor kappaB in non-small cell lung cancer cells.
Naveen Babbar, Amy Hacker, Yi Huang, Robert A Casero

J Biol Chem· August 2006

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Spermine oxidase SMO(PAOh1), Not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines.
Allison Pledgie, Yi Huang, Amy Hacker, Zhe Zhang, Patrick M Woster

J Biol Chem· December 2005

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Properties of recombinant human N1-acetylpolyamine oxidase (hPAO): potential role in determining drug sensitivity.
Yanlin Wang, Amy Hacker, Tracy Murray-Stewart, Benjamin Frydman, Aldonia Valasinas

Cancer Chemother Pharmacol· July 2005

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Induction of human spermine oxidase SMO(PAOh1) is regulated at the levels of new mRNA synthesis, mRNA stabilization and newly synthesized protein.
Yanlin Wang, Amy Hacker, Tracy Murray-Stewart, Jennifer G Fleischer, Patrick M Woster

Biochem J· March 2005

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Spermine causes loss of innate immune response to Helicobacter pylori by inhibition of inducible nitric-oxide synthase translation.
Françoise I Bussière, Rupesh Chaturvedi, Yulan Cheng, Alain P Gobert, Mohammad Asim, Amy Hacker

J Biol Chem· January 2005

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Spermine oxidation induced by Helicobacter pylori results in apoptosis and DNA damage: implications for gastric carcinogenesis.
Hangxiu Xu, Rupesh Chaturvedi, Yulan Cheng, Francoise I Bussiere, Mohammad Asim, Amy Hacker

Cancer Res· December 2004

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Induction of polyamine oxidase 1 by Helicobacter pylori causes macrophage apoptosis by hydrogen peroxide release and mitochondrial membrane depolarization.
Rupesh Chaturvedi, Yulan Cheng, Mohammad Asim, Françoise I Bussière, Hangxiu Xu, Amy Hacker

J Biol Chem· September 2004

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Induction of spermidine/spermine N1-acetyltransferase in breast cancer tissues treated with the polyamine analogue N1, N11-diethylnorspermine.
Edward Gabrielson, Ellen Tully, Amy Hacker, Anthony E Pegg, Nancy E Davidson

Cancer Chemother Pharmacol· August 2004

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Protective role of arginase in a mouse model of colitis.
Alain P Gobert, Yulan Cheng, Mahmood Akhtar, Benjamin D Mersey, Darren R Blumberg, Amy Hacker

J Immunol· August 2004

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Regulation of polyamine analogue cytotoxicity by c-Jun in human MDA-MB-435 cancer cells.
Yi Huang, Judith C Keen, Erin Hager, Renee Smith, Amy Hacker

Mol Cancer Res· February 2004

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Induction of the PAOh1/SMO polyamine oxidase by polyamine analogues in human lung carcinoma cells.
Wendy Devereux, Yanlin Wang, Tracy Murray Stewart, Amy Hacker, Renee Smith

Cancer Chemother Pharmacol· November 2003

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Spermidine/spermine N1-acetyltransferase (SSAT) activity in human small-cell lung carcinoma cells following transfection with a genomic SSAT construct.
Tracy Murray-Stewart, Nancy B Applegren, Wendy Devereux, Amy Hacker, Renee Smith

Biochem J· July 2003

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A novel polyamine analog inhibits growth and induces apoptosis in human breast cancer cells.
Yi Huang, Erin R Hager, Dawn L Phillips, Valerie R Dunn, Amy Hacker

Clin Cancer Res· July 2003

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Properties of purified recombinant human polyamine oxidase, PAOh1/SMO.
Yanlin Wang, Tracy Murray-Stewart, Wendy Devereux, Amy Hacker, Benjamin Frydman

Biochem Biophys Res Commun· May 2003

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Growth status significantly affects the response of human lung cancer cells to antitumor polyamine-analogue exposure.
Diane L Carlisle, Wendy L Devereux, Amy Hacker, Patrick M Woster, Robert A Casero

Clin Cancer Res· August 2002

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