Publications by authors named "Amy M Weeks"

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Enzymatic bromination of native peptides for late-stage structural diversification via Suzuki-Miyaura coupling.
Haley N Bridge, Chase L Radziej, Amy M Weeks

bioRxiv· December 2025

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A self-organizing single-cell morphology circuit optimizes predatory trap structure.
Zhejing Xu, Lauren E Mazurkiewicz, Marine Olivetta, Marisol Morrissey, Omaya Dudin, Amy M Weeks

bioRxiv· November 2025

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Engineered reactivity of a bacterial E1-like enzyme enables ATP-driven modification of protein and peptide C termini.
Clara L Frazier, Debashrito Deb, William E Leiter, Umasankar Mondal, Amy M Weeks

Nat Chem· September 2025

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Phosphoproteome-derived peptide libraries for deep specificity profiling of phosphatases and phospholyases.
Katarzyna Radziwon, Laura A Campbell, Lauren E Mazurkiewicz, Sopo Jalalishvili, Izabelle Eppinger, Amy M Weeks

bioRxiv· August 2025

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PEARLs of wisdom for ribosome-independent peptide bond synthesis.
Amy M Weeks

Proc Natl Acad Sci U S A· April 2025

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Hookworm genes encoding intestinal excreted-secreted proteins are transcriptionally upregulated in response to the host's immune system.
Erich M Schwarz, Jason B Noon, Jeffrey D Chicca, Carli Garceau, Hanchen Li, Amy M Weeks

bioRxiv· February 2025

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Spc2 modulates substrate- and cleavage site-selection in the yeast signal peptidase complex.
Yeonji Chung, Chewon Yim, Gilberto P Pereira, Sungjoon Son, Lisbeth R Kjølbye, Amy M Weeks

J Cell Biol· December 2024

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Engineered reactivity of a bacterial E1-like enzyme enables ATP-driven modification of protein C termini.
Clara L Frazier, Debashrito Deb, Amy M Weeks

bioRxiv· May 2024

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An N terminomics toolbox combining 2-pyridinecarboxaldehyde probes and click chemistry for profiling protease specificity.
Haley N Bridge, William Leiter, Clara L Frazier, Amy M Weeks

Cell Chem Biol· March 2024

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Proteome-Derived Peptide Libraries for Deep Specificity Profiling of N-terminal Modification Reagents.
Haley N Bridge, Amy M Weeks

Curr Protoc· June 2023

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Direct Identification of Proteolytic Cleavages on Living Cells Using a Glycan-Tethered Peptide Ligase.
Kaitlin Schaefer, Irene Lui, James R Byrnes, Emily Kang, Jie Zhou, Amy M Weeks

ACS Cent Sci· October 2022

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Mapping Cell Surface Proteolysis with Plasma Membrane-Targeted Subtiligase.
Aspasia A Amiridis, Amy M Weeks

Methods Mol Biol· May 2022

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Hypoxia Is a Dominant Remodeler of the Effector T Cell Surface Proteome Relative to Activation and Regulatory T Cell Suppression.
James R Byrnes, Amy M Weeks, Eric Shifrut, Julia Carnevale, Lisa Kirkemo

Mol Cell Proteomics· April 2022

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Kinases leave their mark on caspase substrates.
Amy M Weeks

Biochem J· September 2021

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Spatially Resolved Tagging of Proteolytic Neo-N termini with Subtiligase-TM.
Amy M Weeks

J Membr Biol· April 2021

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Protein engineering for selective proteomics.
Katarzyna Radziwon, Amy M Weeks

Curr Opin Chem Biol· February 2021

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Mapping proteolytic neo-N termini at the surface of living cells.
Amy M Weeks, James R Byrnes, Irene Lui, James A Wells

Proc Natl Acad Sci U S A· February 2021

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Engineered peptide ligases for cell signaling and bioconjugation.
Clara L Frazier, Amy M Weeks

Biochem Soc Trans· June 2020

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Subtiligase-Catalyzed Peptide Ligation.
Amy M Weeks, James A Wells

Chem Rev· March 2020

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N-Terminal Modification of Proteins with Subtiligase Specificity Variants.
Amy M Weeks, James A Wells

Curr Protoc Chem Biol· March 2020

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Entropy drives selective fluorine recognition in the fluoroacetyl-CoA thioesterase from .
Amy M Weeks, Ningkun Wang, Jeffrey G Pelton, Michelle C Y Chang

Proc Natl Acad Sci U S A· March 2018

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Engineering peptide ligase specificity by proteomic identification of ligation sites.
Amy M Weeks, James A Wells

Nat Chem Biol· January 2018

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Redox-based reagents for chemoselective methionine bioconjugation.
Shixian Lin, Xiaoyu Yang, Shang Jia, Amy M Weeks, Michael Hornsby

Science· February 2017

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Molecular recognition of fluorine impacts substrate selectivity in the fluoroacetyl-CoA thioesterase FlK.
Amy M Weeks, Neil S Keddie, Rudy D P Wadoux, David O'Hagan, Michelle C Y Chang

Biochemistry· April 2014

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C
Catalytic control of enzymatic fluorine specificity.
Amy M Weeks, Michelle C Y Chang

Proc Natl Acad Sci U S A· November 2012

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