Publications by authors named "Amy R Howell"

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2-Halomethyleneoxetanes from 2-Methyleneoxetanes by Reaction with -Halosuccinimides: Reactant Influences on Stereochemical Outcomes and Reaction Pathways.
Dennis Sulwey, Julia B DiSapio, José A Gascón, Amy R Howell

J Org Chem· November 2024

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A Humanized Mouse Model Coupled with Computational Analysis Identifies Potent Glycolipid Agonist of Invariant NKT Cells.
Noemi A Saavedra-Avila, Natalia B Pigni, Donald R Caldwell, Florencia Chena-Becerra, Jose Intano, Amy R Howell

ACS Chem Biol· April 2024

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1,6-Dioxo-2-azaspiro[3.4]oct-2-enes and Related Spirocycles: Heterocycles from [3 + 2] Nitrile Oxide Cycloadditions with 2-Methyleneoxetanes, -Thietanes, and -Azetidines.
Jose Intano, Louis P Riel, Jacky Lim, Jerome R Robinson, Amy R Howell

J Org Chem· December 2023

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Lysosomal processing of sulfatide analogs alters target NKT cell specificity and immune responses in cancer.
Kumiko Nishio, Lise Pasquet, Kaddy Camara, Julia DiSapio, Kevin S Hsu, Amy R Howell

J Clin Invest· December 2023

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A humanized mouse model for evaluation of invariant Natural Killer T cell responses.
Noemi Alejandra Saavedra-Avila, Paolo Dellabona, Giulia Casorati, Natacha Veerapen, Gurdyal S Besra, Amy R Howell

Front Immunol· October 2022

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Chemical proteomic analysis of palmostatin beta-lactone analogs that affect N-Ras palmitoylation.
Radu M Suciu, Irungu K Luvaga, Akram Hazeen, Chulangani Weerasooriya, Stewart K Richardson, Amy R Howell

Bioorg Med Chem Lett· December 2021

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Unusual Transformations of Strain-Heightened Oxetanes.
Jason An, Louis P Riel, Amy R Howell

Acc Chem Res· October 2021

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ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth.
Jarrett R Remsberg, Radu M Suciu, Noemi A Zambetti, Thomas W Hanigan, Ari J Firestone, Amy R Howell

Nat Chem Biol· August 2021

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Easily accessible non-aromatic heterocycles with handles: 4-bromo-2,3-dihydrofurans from 1,2-dibromohomoallylic alcohols.
Jason An, Jose Intano, Alissa Richard, Taehyun Kim, José A Gascón, Amy R Howell

Chem Sci· August 2021

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α-Methylene-β-Lactone Scaffold for Developing Chemical Probes at the Two Ends of the Selectivity Spectrum.
Lei Wang, Louis P Riel, Bekim Bajrami, Bin Deng, Amy R Howell

Chembiochem· February 2021

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Amide-Linked C4″-Saccharide Modification of KRN7000 Provides Potent Stimulation of Human Invariant NKT Cells and Anti-Tumor Immunity in a Humanized Mouse Model.
Noemi Alejandra Saavedra-Avila, Santosh Keshipeddy, Matthew J Guberman-Pfeffer, Ayax Pérez-Gallegos, Neeraj K Saini, Amy R Howell

ACS Chem Biol· December 2020

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A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response.
Roeland Lameris, Adam Shahine, Daniel G Pellicci, Adam P Uldrich, Stephanie Gras, Amy R Howell

Nat Cancer· November 2020

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Immunomodulatory sphingosine-1-phosphates as plasma biomarkers of Alzheimer's disease and vascular cognitive impairment.
Xin Ying Chua, Yuek Ling Chai, Wee Siong Chew, Joyce R Chong, Hui Li Ang, Amy R Howell

Alzheimers Res Ther· September 2020

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Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae.
Shilpi Chandra, James Gray, William B Kiosses, Archana Khurana, Kaori Hitomi, Amy R Howell

Nat Commun· October 2018

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Heterogeneous Catalytic Oxidation of Amides to Imides by Manganese Oxides.
Sourav Biswas, Harshul S Khanna, Quddus A Nizami, Donald R Caldwell, Katherine T Cavanaugh, Amy R Howell

Sci Rep· September 2018

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Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity.
Divya Chennamadhavuni, Noemi Alejandra Saavedra-Avila, Leandro J Carreño, Matthew J Guberman-Pfeffer, Pooja Arora, Amy R Howell

Cell Chem Biol· July 2018

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Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity.
Divya Chennamadhavuni, Noemi Alejandra Saavedra-Avila, Leandro J Carreño, Matthew J Guberman-Pfeffer, Pooja Arora, Amy R Howell

Cell Chem Biol· May 2018

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Rh-Catalyzed Conjugate Addition of Aryl and Alkenyl Boronic Acids to α-Methylene-β-lactones: Stereoselective Synthesis of trans-3,4-Disubstituted β-Lactones.
Christian A Malapit, Irungu K Luvaga, Donald R Caldwell, Nicholas K Schipper, Amy R Howell

Org Lett· September 2017

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Contact sensitizers trigger human CD1-autoreactive T-cell responses.
Richard J Betts, Adrijana Perkovic, Subhashree Mahapatra, Aurélia Del Bufalo, Kaddy Camara, Amy R Howell

Eur J Immunol· July 2017

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Rhodium-Catalyzed Addition of Aryl Boronic Acids to 2,2-Disubstituted Malononitriles.
Christian A Malapit, Donald R Caldwell, Irungu K Luvaga, Jonathan T Reeves, Ivan Volchkov, Amy R Howell

Angew Chem Int Ed Engl· June 2017

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Scaling Proteome-Wide Reactions of Activity-Based Probes.
Song Li, Pamela A Diego-Limpin, Bekim Bajrami, Santosh Keshipeddy, Ying-Wai Lam, Amy R Howell

Anal Chem· June 2017

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1,4-Dicarbofunctionalization of 4-Fluoroaryl Grignard and Lithium Reagents with Disubstituted Malononitriles.
Christian A Malapit, Irungu K Luvaga, Jonathan T Reeves, Ivan Volchkov, Carl A Busacca, Amy R Howell

J Org Chem· May 2017

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Pd-Catalyzed Acyl C-O Bond Activation for Selective Ring-Opening of α-Methylene-β-lactones with Amines.
Christian A Malapit, Donald R Caldwell, Nicole Sassu, Samuel Milbin, Amy R Howell

Org Lett· April 2017

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Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.
Jérôme Le Nours, T Praveena, Daniel G Pellicci, Nicholas A Gherardin, Fiona J Ross, Amy R Howell

Nat Commun· February 2016

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Rhodium-Catalyzed Transnitrilation of Aryl Boronic Acids with Dimethylmalononitrile.
Christian A Malapit, Jonathan T Reeves, Carl A Busacca, Amy R Howell, Chris H Senanayake

Angew Chem Int Ed Engl· January 2016

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