Publications by authors named "Amy Strilchuk"

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Harnessing artificial intelligence to advance CRISPR-based genome editing technologies.
Tyler Thomson, Gen Li, Amy Strilchuk, Haotian Cui, Bo Wang

Nat Rev Genet· November 2025

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Safety risks of intratracheal lipid nanoparticle gene delivery to the lung and potential mitigation strategies.
Akihiro Nagoya, Kumi Nakajima, Jenny Yune, Aizhou Wang, Zehong Guan, Amy Strilchuk

J Thorac Cardiovasc Surg· October 2025

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Rational design and modular synthesis of biodegradable ionizable lipids via the Passerini reaction for mRNA delivery.
Yue Xu, Fanglin Gong, Alex Golubovic, Amy Strilchuk, Jingan Chen

Proc Natl Acad Sci U S A· February 2025

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Lipid nanoparticles and siRNA targeting plasminogen provide lasting inhibition of fibrinolysis in mouse and dog models of hemophilia A.
Amy W Strilchuk, Woosuk S Hur, Paul Batty, Yaqiu Sang, Sara R Abrahams

Sci Transl Med· February 2024

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Comparison of DLin-MC3-DMA and ALC-0315 for siRNA Delivery to Hepatocytes and Hepatic Stellate Cells.
Francesca Ferraresso, Amy W Strilchuk, Lih Jiin Juang, Lauren G Poole, James P Luyendyk

Mol Pharm· July 2022

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Suppression of fibrin(ogen)-driven pathologies in disease models through controlled knockdown by lipid nanoparticle delivery of siRNA.
Lih Jiin Juang, Woosuk S Hur, Lakmali M Silva, Amy W Strilchuk, Brenton Francisco

Blood· March 2022

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Nanomedicines for hemorrhage control.
Massimo F Cau, Amy W Strilchuk, Christian J Kastrup

J Thromb Haemost· April 2021

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Sustained depletion of FXIII-A by inducing acquired FXIII-B deficiency.
Amy W Strilchuk, Scott C Meixner, Jerry Leung, Nooshin S Safikhan, Jayesh A Kulkarni

Blood· December 2020

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Bleeding is increased in amyloid precursor protein knockout mouse.
Nima Mazinani, Amy W Strilchuk, James R Baylis, Woosuk S Hur, Wilfred A Jefferies

Res Pract Thromb Haemost· July 2020

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Deubiquitinating enzyme USP30 maintains basal peroxisome abundance by regulating pexophagy.
Victoria Riccio, Nicholas Demers, Rong Hua, Miluska Vissa, Derrick T Cheng, Amy Wong Strilchuk

J Cell Biol· March 2019

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The ubiquitin interacting motifs of USP37 act on the proximal Ub of a di-Ub chain to enhance catalytic efficiency.
Noah Manczyk, Gianluca Veggiani, Joan Teyra, Amy W Strilchuk, Sachdev S Sidhu

Sci Rep· March 2019

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