Publications by authors named "Ana Barbas"

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Aldehyde Dehydrogenase 2 (ALDH2): A novel sorafenib target in hepatocellular carcinoma unraveled by the proteome-wide cellular thermal shift assay.
Inês C Ferreira, Estefania Torrejón, Bernardo Abecasis, Bruno M Alexandre, Ricardo A Gomes, Ana Barbas

SLAS Discov· April 2024

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Novel scFv against Notch Ligand JAG1 Suitable for Development of Cell Therapies toward JAG1-Positive Tumors.
Gabriela Silva, Ana F Rodrigues, Susana Ferreira, Carolina Matos, Rute P Eleutério, Ana Barbas

Biomolecules· March 2023

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Transcriptome and proteome profiling of activated cardiac fibroblasts supports target prioritization in cardiac fibrosis.
Maria Raquel Moita, Marta M Silva, Cláudia Diniz, Margarida Serra, René M Hoet, Ana Barbas

Front Cardiovasc Med· December 2022

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Development of antibodies against the notch ligand Delta-Like-1 by phage display with activity against breast cancer cells.
Joana Sales-Dias, Andreia Ferreira, Márcia Lamy, Giacomo Domenici, Sandra M S Monteiro, Ana Barbas

N Biotechnol· September 2021

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Development of Dl1.72, a Novel Anti-DLL1 Antibody with Anti-Tumor Efficacy against Estrogen Receptor-Positive Breast Cancer.
Gabriela Silva, Joana Sales-Dias, Diogo Casal, Sara Alves, Giacomo Domenici, Ana Barbas

Cancers (Basel)· August 2021

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The Notch ligand DLL1 exerts carcinogenic features in human breast cancer cells.
Joana Sales-Dias, Gabriela Silva, Márcia Lamy, Andreia Ferreira, Ana Barbas

PLoS One· January 2020

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Evaluation of AAV-mediated delivery of shRNA to target basal-like breast cancer genetic vulnerabilities.
Catarina Pinto, Gabriela Silva, Ana S Ribeiro, Mónica Oliveira, Manuel Garrido, Ana Barbas

J Biotechnol· July 2019

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Novel monoclonal antibody L2A5 specifically targeting sialyl-Tn and short glycans terminated by alpha-2-6 sialic acids.
Liliana R Loureiro, Diana P Sousa, Dylan Ferreira, Wengang Chai, Luís Lima, Ana Barbas

Sci Rep· August 2018

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Production and characterization of a novel Delta-like 1 functional unit as a tool for Notch pathway activation and generation of a specific antibody.
Andreia Ferreira, Márcia Lamy, Maria Margarida Rocha, Gabriela Silva, Tiago M Bandeiras, Ana Barbas

Protein Expr Purif· June 2018

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Notch-out for breast cancer therapies.
Márcia Lamy, Andreia Ferreira, Joana Sales Dias, Sofia Braga, Gabriela Silva, Ana Barbas

N Biotechnol· October 2017

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Retroviral particles are effectively purified on an affinity matrix containing peptides selected by phage-display.
Cláudia S M Fernandes, Inês Barbosa, Rute Castro, Ana Sofia Pina, Ana Sofia Coroadinha, Ana Barbas

Biotechnol J· December 2016

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Correction: Modulating the RNA Processing and Decay by the Exosome: Altering Rrp44/Dis3 Activity and End-Product.
Filipa P Reis, Ana Barbas, A A Klauer-King, Borislava Tsanova, Daneen Schaeffer

PLoS One· October 2015

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Challenges in Antibody Development against Tn and Sialyl-Tn Antigens.
Liliana R Loureiro, Mylène A Carrascal, Ana Barbas, José S Ramalho, Carlos Novo

Biomolecules· August 2015

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Modulating the RNA processing and decay by the exosome: altering Rrp44/Dis3 activity and end-product.
Filipa P Reis, Ana Barbas, A A Klauer-King, Borislava Tsanova, Daneen Schaeffer

PLoS One· July 2014

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Rossmann-fold motifs can confer multiple functions to metabolic enzymes: RNA binding and ribonuclease activity of a UDP-glucose dehydrogenase.
Ana Barbas, Alma Popescu, Carlos Frazão, Cecília M Arraiano, Arsénio M Fialho

Biochem Biophys Res Commun· January 2013

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Swapping the domains of exoribonucleases RNase II and RNase R: conferring upon RNase II the ability to degrade ds RNA.
Rute Gonçalves Matos, Ana Barbas, Paulino Gómez-Puertas, Cecília Maria Arraiano

Proteins· June 2011

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RNase II: the finer details of the Modus operandi of a molecular killer.
Cecilia M Arraiano, Rute G Matos, Ana Barbas

RNA Biol· February 2011

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Comparison of EMSA and SPR for the characterization of RNA-RNase II complexes.
Rute G Matos, Ana Barbas, Cecília M Arraiano

Protein J· August 2010

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Biochemical characterization of the RNase II family of exoribonucleases from the human pathogens Salmonella typhimurium and Streptococcus pneumoniae.
Susana Domingues, Rute G Matos, Filipa P Reis, Arsénio M Fialho, Ana Barbas

Biochemistry· December 2009

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RNase R mutants elucidate the catalysis of structured RNA: RNA-binding domains select the RNAs targeted for degradation.
Rute Gonçalves Matos, Ana Barbas, Cecília Maria Arraiano

Biochem J· September 2009

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Determination of key residues for catalysis and RNA cleavage specificity: one mutation turns RNase II into a "SUPER-ENZYME".
Ana Barbas, Rute G Matos, Mónica Amblar, Eduardo López-Viñas, Paulino Gomez-Puertas

J Biol Chem· July 2009

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Characterizing ribonucleases in vitro examples of synergies between biochemical and structural analysis.
Cecília Maria Arraiano, Ana Barbas, Mónica Amblar

Methods Enzymol· March 2009

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The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities.
Daneen Schaeffer, Borislava Tsanova, Ana Barbas, Filipa Pereira Reis, Eeshita Ghosh Dastidar

Nat Struct Mol Biol· January 2009

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New insights into the mechanism of RNA degradation by ribonuclease II: identification of the residue responsible for setting the RNase II end product.
Ana Barbas, Rute G Matos, Mónica Amblar, Eduardo López-Viñas, Paulino Gomez-Puertas

J Biol Chem· May 2008

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The role of the S1 domain in exoribonucleolytic activity: substrate specificity and multimerization.
Mónica Amblar, Ana Barbas, Paulino Gomez-Puertas, Cecília M Arraiano

RNA· March 2007

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