Publications by authors named "Anastasios Georgakopoulos"

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A Robust End-to-End IoT System for Supporting Workers in Mining Industries.
Marios Vlachos, Lampros Pavlopoulos, Anastasios Georgakopoulos, Georgios Tsimiklis, Angelos Amditis

Sensors (Basel)· May 2024

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3D AFM Nanomechanical Characterization of Biological Materials.
Stylianos Vasileios Kontomaris, Andreas Stylianou, Anastasios Georgakopoulos, Anna Malamou

Nanomaterials (Basel)· January 2023

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Adherens junctions organize size-selective proteolytic hotspots critical for Notch signalling.
Minsuk Kwak, Kaden M Southard, Woon Ryoung Kim, Annie Lin, Nam Hyeong Kim, Anastasios Georgakopoulos

Nat Cell Biol· December 2022

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PS1 FAD mutants decrease ephrinB2-regulated angiogenic functions, ischemia-induced brain neovascularization and neuronal survival.
YoneJung Yoon, Georgios Voloudakis, Nathan Doran, Emily Zhang, Christina Dimovasili, Anastasios Georgakopoulos

Mol Psychiatry· June 2021

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Presenilin1 familial Alzheimer disease mutants inactivate EFNB1- and BDNF-dependent neuroprotection against excitotoxicity by affecting neuroprotective complexes of -methyl-d-aspartate receptor.
Md Al Rahim, Yonejung Yoon, Christina Dimovasili, Zhiping Shao, Qian Huang, Anastasios Georgakopoulos

Brain Commun· July 2020

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The product of the γ-secretase processing of ephrinB2 regulates VE-cadherin complexes and angiogenesis.
Noel A Warren, Georgios Voloudakis, Yonejung Yoon, Nikolaos K Robakis, Anastasios Georgakopoulos

Cell Mol Life Sci· August 2018

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Presenilin1/γ-secretase protects neurons from glucose deprivation-induced death by regulating miR-212 and PEA15.
Qian Huang, Georgios Voloudakis, Yimin Ren, Yonejung Yoon, Emily Zhang, Anastasios Georgakopoulos

FASEB J· January 2018

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Presenilin 1 promotes trypsin-induced neuroprotection via the PAR2/ERK signaling pathway. Effects of presenilin 1 FAD mutations.
Angeliki M Nikolakopoulou, Anastasios Georgakopoulos, Nikolaos K Robakis

Neurobiol Aging· June 2016

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Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia.
José L Moreno, Patricia Miranda-Azpiazu, Aintzane García-Bea, Jason Younkin, Meng Cui, Anastasios Georgakopoulos

Sci Signal· January 2016

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Presenilin 1 is necessary for neuronal, but not glial, EGFR expression and neuroprotection via γ-secretase-independent transcriptional mechanisms.
Julien Bruban, Georgios Voloudakis, Qian Huang, Yuji Kajiwara, Md Al Rahim, Anastasios Georgakopoulos

FASEB J· September 2015

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A role for noncoding variation in schizophrenia.
Panos Roussos, Amanda C Mitchell, Georgios Voloudakis, John F Fullard, Venu M Pothula, Anastasios Georgakopoulos

Cell Rep· November 2014

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Allelic interference: a mechanism for trans-dominant transmission of loss of function in the neurodegeneration of familial Alzheimer's disease.
Nikolaos K Robakis, Anastasios Georgakopoulos

Neurodegener Dis· September 2014

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Presenilin-1/γ-secretase controls glutamate release, tyrosine phosphorylation, and surface expression of N-methyl-D-aspartate receptor (NMDAR) subunit GluN2B.
Zhao Xuan, Gael Barthet, Junichi Shioi, Jindong Xu, Anastasios Georgakopoulos

J Biol Chem· October 2013

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Presenilin mediates neuroprotective functions of ephrinB and brain-derived neurotrophic factor and regulates ligand-induced internalization and metabolism of EphB2 and TrkB receptors.
Gael Barthet, Julie Dunys, Zhiping Shao, Zhao Xuan, Yimin Ren, Anastasios Georgakopoulos

Neurobiol Aging· February 2013

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Cellular mechanisms of γ-secretase substrate selection, processing and toxicity.
Gael Barthet, Anastasios Georgakopoulos, Nikolaos K Robakis

Prog Neurobiol· August 2012

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Presenilin1/gamma-secretase promotes the EphB2-induced phosphorylation of ephrinB2 by regulating phosphoprotein associated with glycosphingolipid-enriched microdomains/Csk binding protein.
Anastasios Georgakopoulos, Jindong Xu, Chijie Xu, Gweltas Mauger, Gael Barthet

FASEB J· October 2011

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Inhibitors of γ-secretase stabilize the complex and differentially affect processing of amyloid precursor protein and other substrates.
Gael Barthet, Junichi Shioi, Zhiping Shao, Yimin Ren, Anastasios Georgakopoulos

FASEB J· September 2011

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The association of schizophrenia risk D-amino acid oxidase polymorphisms with sensorimotor gating, working memory and personality in healthy males.
Panos Roussos, Stella G Giakoumaki, Eva Adamaki, Anastasios Georgakopoulos, Nikos K Robakis

Neuropsychopharmacology· July 2011

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The CACNA1C and ANK3 risk alleles impact on affective personality traits and startle reactivity but not on cognition or gating in healthy males.
Panos Roussos, Stella G Giakoumaki, Anastasios Georgakopoulos, Nikolaos K Robakis, Panos Bitsios

Bipolar Disord· May 2011

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Phosphatidylinositol-4,5-bisphosphate regulates epidermal growth factor receptor activation.
Ioannis E Michailidis, Radda Rusinova, Anastasios Georgakopoulos, Yibang Chen, Ravi Iyengar

Pflugers Arch· March 2011

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Peptide EphB2/CTF2 generated by the gamma-secretase processing of EphB2 receptor promotes tyrosine phosphorylation and cell surface localization of N-methyl-D-aspartate receptors.
Jindong Xu, Claudia Litterst, Anastasios Georgakopoulos, Ioannis Zaganas, Nikolaos K Robakis

J Biol Chem· October 2009

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p120 catenin recruits cadherins to gamma-secretase and inhibits production of Abeta peptide.
Zen Kouchi, Gael Barthet, Geo Serban, Anastasios Georgakopoulos, Junichi Shioi

J Biol Chem· January 2009

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Wild-type but not FAD mutant presenilin-1 prevents neuronal degeneration by promoting phosphatidylinositol 3-kinase neuroprotective signaling.
Lia Baki, Rachael L Neve, Zhiping Shao, Junichi Shioi, Anastasios Georgakopoulos

J Neurosci· January 2008

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Ligand binding and calcium influx induce distinct ectodomain/gamma-secretase-processing pathways of EphB2 receptor.
Claudia Litterst, Anastasios Georgakopoulos, Junichi Shioi, Enrico Ghersi, Thomas Wisniewski

J Biol Chem· June 2007

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FAD mutants unable to increase neurotoxic Abeta 42 suggest that mutation effects on neurodegeneration may be independent of effects on Abeta.
Junichi Shioi, Anastasios Georgakopoulos, Pankaj Mehta, Zen Kouchi, Claudia M Litterst

J Neurochem· May 2007

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