Publications by authors named "Anastasios Karadimitris"

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Off-the-shelf dual CAR-iNKT cell immunotherapy eradicates medullary and leptomeningeal high-risk KMT2A-rearranged leukemia.
Hongwei Ren, Natalina Elliott, Bryan Lye, Mohammad Umer Sharif Shohan, Joe Wilson Cross, Anastasios Karadimitris

Blood· September 2025

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Harnessing Single-Cell Technologies in the Search for New Therapies for Diamond-Blackfan Anemia Syndrome.
Deena Iskander, Anastasios Karadimitris, Irene Roberts

Exp Hematol· July 2024

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MAF functions as a pioneer transcription factor that initiates and sustains myelomagenesis.
Alexia Katsarou, Nikolaos Trasanidis, Kanagaraju Ponnusamy, Ioannis V Kostopoulos, Jaime Alvarez-Benayas, Anastasios Karadimitris

Blood Adv· November 2023

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Diamond-Blackfan anemia in adults: In pursuit of a common approach for a rare disease.
Deena Iskander, Noémi B A Roy, Elspeth Payne, Emma Drasar, Kelly Hennessy, Anastasios Karadimitris

Blood Rev· September 2023

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CAR-iNKT cells targeting clonal TCRVβ chains as a precise strategy to treat T cell lymphoma.
Aileen G Rowan, Kanagaraju Ponnusamy, Hongwei Ren, Graham P Taylor, Lucy B M Cook, Anastasios Karadimitris

Front Immunol· March 2023

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A Phase I/II Open-Label Study of Molibresib for the Treatment of Relapsed/Refractory Hematologic Malignancies.
Mark A Dawson, Gautam Borthakur, Brian J P Huntly, Anastasios Karadimitris, Adrian Alegre

Clin Cancer Res· February 2023

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The innate sensor ZBP1-IRF3 axis regulates cell proliferation in multiple myeloma.
Kanagaraju Ponnusamy, Maria Myrsini Tzioni, Murshida Begum, Mark E Robinson, Valentina S Caputo, Anastasios Karadimitris

Haematologica· March 2022

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Systems medicine dissection of chr1q-amp reveals a novel PBX1-FOXM1 axis for targeted therapy in multiple myeloma.
Nikolaos Trasanidis, Alexia Katsarou, Kanagaraju Ponnusamy, Yao-An Shen, Ioannis V Kostopoulos, Anastasios Karadimitris

Blood· March 2022

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Single-cell profiling of human bone marrow progenitors reveals mechanisms of failing erythropoiesis in Diamond-Blackfan anemia.
Deena Iskander, Guanlin Wang, Elisabeth F Heuston, Chrysi Christodoulidou, Bethan Psaila, Anastasios Karadimitris

Sci Transl Med· September 2021

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Chromatin-based, in cis and in trans regulatory rewiring underpins distinct oncogenic transcriptomes in multiple myeloma.
Jaime Alvarez-Benayas, Nikolaos Trasanidis, Alexia Katsarou, Kanagaraju Ponnusamy, Aristeidis Chaidos, Anastasios Karadimitris

Nat Commun· September 2021

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Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development.
Anindita Roy, Guanlin Wang, Deena Iskander, Sorcha O'Byrne, Natalina Elliott, Anastasios Karadimitris

Cell Rep· September 2021

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Systems level profiling of chemotherapy-induced stress resolution in cancer cells reveals druggable trade-offs.
Paula Saavedra-García, Monica Roman-Trufero, Hibah A Al-Sadah, Kevin Blighe, Elena López-Jiménez, Anastasios Karadimitris

Proc Natl Acad Sci U S A· April 2021

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Transcriptional analysis of multiple ovarian cancer cohorts reveals prognostic and immunomodulatory consequences of ERV expression.
Marina Natoli, John Gallon, Haonan Lu, Ala Amgheib, David J Pinato, Anastasios Karadimitris

J Immunother Cancer· January 2021

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Brd2/4 and Myc regulate alternative cell lineage programmes during early osteoclast differentiation in vitro.
Valentina S Caputo, Nikolaos Trasanidis, Xiaolin Xiao, Mark E Robinson, Alexia Katsarou, Anastasios Karadimitris

iScience· January 2021

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Paroxysmal nocturnal haemoglobinuria (PNH): novel therapies for an ancient disease.
Lucio Luzzatto, Anastasios Karadimitris

Br J Haematol· November 2020

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Interleukin 6-blockade treatment for severe COVID-19 in two patients with multiple myeloma.
Aristeidis Chaidos, Alexia Katsarou, Chira Mustafa, Dragana Milojkovic, Anastasios Karadimitris

Br J Haematol· July 2020

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Cord Blood CAR-NK Cells: Favorable Initial Efficacy and Toxicity but Durability of Clinical Responses Not Yet Clear.
Anastasios Karadimitris

Cancer Cell· April 2020

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Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs.
Sorcha O'Byrne, Natalina Elliott, Siobhan Rice, Gemma Buck, Nicholas Fordham, Anastasios Karadimitris

Blood· September 2019

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Impaired cellular and humoral immunity is a feature of Diamond-Blackfan anaemia; experience of 107 unselected cases in the United Kingdom.
Deena Iskander, Irene Roberts, Clare Rees, Richard Szydlo, Mary Alikian, Anastasios Karadimitris

Br J Haematol· July 2019

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Invariant NKT cells as a platform for CAR immunotherapy and prevention of acute Graft-versus-Host Disease.
Anastasios Karadimitris, Carme Ripoll-Fiol, Jose Costa Guerra

Hemasphere· June 2019

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Impact of route and adequacy of nutritional intake on outcomes of allogeneic haematopoietic cell transplantation for haematologic malignancies.
Julie Beckerson, Richard M Szydlo, Mary Hickson, Catriona E Mactier, Andrew J Innes, Anastasios Karadimitris

Clin Nutr· April 2019

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The coordinated action of VCP/p97 and GCN2 regulates cancer cell metabolism and proteostasis during nutrient limitation.
Katarzyna Parzych, Paula Saavedra-García, Gabriel N Valbuena, Hibah A Al-Sadah, Mark E Robinson, Anastasios Karadimitris

Oncogene· April 2019

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Enhanced Anti-lymphoma Activity of CAR19-iNKT Cells Underpinned by Dual CD19 and CD1d Targeting.
Antonia Rotolo, Valentina S Caputo, Monika Holubova, Nicoleta Baxan, Olivier Dubois, Anastasios Karadimitris

Cancer Cell· October 2018

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Building upon the success of CART19: chimeric antigen receptor T cells for hematologic malignancies.
Antonia Rotolo, Anastasios Karadimitris, Marco Ruella

Leuk Lymphoma· September 2018

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High resolution IgH repertoire analysis reveals fetal liver as the likely origin of life-long, innate B lymphopoiesis in humans.
Anindita Roy, Vojtech Bystry, Georg Bohn, Katerina Goudevenou, Tomas Reigl, Anastasios Karadimitris

Clin Immunol· October 2017

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