Publications by authors named "Andre A Grassmann"

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DNA Binding by BosR Controls RpoS-Dependent and -Independent Gene Expression in Borrelia burgdorferi.
André A Grassmann, Melissa A McLain, Michael R Freeman, Melissa J Caimano, Justin D Radolf

Mol Microbiol· November 2025

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Sequence variability of BamA and FadL candidate vaccinogens suggests divergent evolutionary paths of outer membrane proteins.
Everton B Bettin, Farhang Aghakhanian, Christopher M Hennelly, Wentao Chen, Timothy C Davenport, Andre A Grassmann

J Bacteriol· August 2025

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Immunodominant extracellular loops of Treponema pallidum FadL outer membrane proteins elicit antibodies with opsonic and growth-inhibitory activities.
Kristina N Delgado, Melissa J Caimano, Isabel C Orbe, Crystal F Vicente, Carson J La Vake, André A Grassmann

PLoS Pathog· December 2024

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Leptospira interrogans encodes a canonical BamA and three novel noNterm Omp85 outer membrane protein paralogs.
Everton B Bettin, André A Grassmann, Odir A Dellagostin, Johann Peter Gogarten, Melissa J Caimano

Sci Rep· August 2024

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Immunodominant extracellular loops of FadL outer membrane proteins elicit antibodies with opsonic and growth-inhibitory activities.
Kristina N Delgado, Melissa J Caimano, Isabel C Orbe, Crystal F Vicente, Carson J La Vake, André A Grassmann

bioRxiv· July 2024

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BosR and PlzA reciprocally regulate RpoS function to sustain Borrelia burgdorferi in ticks and mammals.
André A Grassmann, Rafal Tokarz, Caroline Golino, Melissa A McLain, Ashley M Groshong

J Clin Invest· March 2023

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Challenges for the development of a universal vaccine against leptospirosis revealed by the evaluation of 22 vaccine candidates.
Mara A C Maia, Everton B Bettin, Liana N Barbosa, Natasha R de Oliveira, Tiffany T Bunde, André A Grassmann

Front Cell Infect Microbiol· October 2022

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TonB-dependent receptor epitopes expressed in M. bovis BCG induced significant protection in the hamster model of leptospirosis.
Everton B Bettin, Jessica Dorneles, Amanda S Hecktheuer, Andriele B Madruga, Amilton C P Seixas Neto, André A Grassmann

Appl Microbiol Biotechnol· January 2022

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The FUR-like regulators PerRA and PerRB integrate a complex regulatory network that promotes mammalian host-adaptation and virulence of Leptospira interrogans.
André A Grassmann, Crispin Zavala-Alvarado, Everton B Bettin, Mathieu Picardeau, Nadia Benaroudj

PLoS Pathog· December 2021

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PlzA is a bifunctional c-di-GMP biosensor that promotes tick and mammalian host-adaptation of Borrelia burgdorferi.
Ashley M Groshong, André A Grassmann, Amit Luthra, Melissa A McLain, Anthony A Provatas

PLoS Pathog· July 2021

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Cultivation of Leptospira interrogans Within Rat Peritoneal Dialysis Membrane Chambers.
Andre Alex Grassmann, Melissa J Caimano

Methods Mol Biol· March 2021

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Role of glucosyltransferase R in biofilm interactions between Streptococcus oralis and Candida albicans.
João Gabriel Silva Souza, Martinna Bertolini, Angela Thompson, Jillian M Mansfield, André Alex Grassmann

ISME J· May 2020

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Pathogenic Leptospires Modulate Protein Expression and Post-translational Modifications in Response to Mammalian Host Signals.
Jarlath E Nally, Andre A Grassmann, Sébastien Planchon, Kjell Sergeant, Jenny Renaut

Front Cell Infect Microbiol· April 2018

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Discovery of Novel Leptospirosis Vaccine Candidates Using Reverse and Structural Vaccinology.
André Alex Grassmann, Frederico Schmitt Kremer, Júlia Cougo Dos Santos, Jéssica Dias Souza, Luciano da Silva Pinto

Front Immunol· April 2017

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A Universal Vaccine against Leptospirosis: Are We Going in the Right Direction?
André Alex Grassmann, Jéssica Dias Souza, Alan John Alexander McBride

Front Immunol· March 2017

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Reverse Vaccinology: An Approach for Identifying Leptospiral Vaccine Candidates.
Odir A Dellagostin, André A Grassmann, Caroline Rizzi, Rodrigo A Schuch, Sérgio Jorge

Int J Mol Sci· January 2017

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Lectin I from Bauhinia variegata (BVL-I) expressed by Pichia pastoris inhibits initial adhesion of oral bacteria in vitro.
Gabriel Baracy Klafke, Gustavo Marçal Schmidt Garcia Moreira, Juliano Lacava Pereira, Patrícia Diaz Oliveira, Fabricio Rochedo Conceição, André Alex Grassmann

Int J Biol Macromol· December 2016

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Evaluation of the Leptospira interrogans Outer Membrane Protein OmpL37 as a Vaccine Candidate.
Thaís Larré Oliveira, André Alex Grassmann, Rodrigo Andrade Schuch, Amilton Clair Pinto Seixas Neto, Marcelo Mendonça

PLoS One· June 2016

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Draft genome of the Leptospira interrogans strains, Acegua, RCA, Prea, and Capivara, obtained from wildlife maintenance hosts and infected domestic animals.
Frederico S Kremer, Marcus R Eslabão, Sérgio Jorge, Natasha R Oliveira, Julia Labonde, André A Grassmann

Mem Inst Oswaldo Cruz· April 2016

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Generation of Mammalian Host-adapted by Cultivation in Peritoneal Dialysis Membrane Chamber Implantation in Rats.
André Alex Grassmann, Alan John Alexander McBride, Jarlath E Nally, Melissa J Caimano

Bio Protoc· July 2015

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A model system for studying the transcriptomic and physiological changes associated with mammalian host-adaptation by Leptospira interrogans serovar Copenhageni.
Melissa J Caimano, Sathesh K Sivasankaran, Anna Allard, Daniel Hurley, Karsten Hokamp, André A Grassmann

PLoS Pathog· March 2014

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Protection against lethal leptospirosis after vaccination with LipL32 coupled or coadministered with the B subunit of Escherichia coli heat-labile enterotoxin.
André A Grassmann, Samuel R Félix, Carolina Ximendes dos Santos, Marta G Amaral, Amilton C P Seixas Neto

Clin Vaccine Immunol· May 2012

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Recombinant vaccines against leptospirosis.
Odir A Dellagostin, André A Grassmann, Daiane D Hartwig, Samuel R Félix, Éverton F da Silva

Hum Vaccin· November 2011

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Highly virulent Leptospira borgpetersenii strain characterized in the hamster model.
Juliana Alcoforado Diniz, Samuel Rodrigues Félix, Josiane Bonel-Raposo, Amilton Clair Pinto Seixas Neto, Flávia Aleixo Vasconcellos, André Alex Grassmann

Am J Trop Med Hyg· August 2011

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Preliminary characterization of Mus musculus-derived pathogenic strains of Leptospira borgpetersenii serogroup Ballum in a hamster model.
Everton F da Silva, Samuel R Félix, Gustavo M Cerqueira, Michel Q Fagundes, Amilton C P S Neto, André A Grassmann

Am J Trop Med Hyg· August 2010

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