Publications by authors named "Andre Bachmann"

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Genetic and Phenotypic Features of the Five Known Polyaminopathies: A Critical Narrative Review.
Elizabeth A VanSickle, Sara M Sarasua, Tracy Lowe, Christopher L Farrell, Luigi Boccuto, André S Bachmann

Am J Med Genet A· December 2025

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Integration of Design of Experiments for the Development and Evaluation of Sulfasalazine Loaded Hybrid Albumin Chitosan Based Polymeric Nanocarriers.
Sushrut Marathe, Rohit Joshi, Rongbing Yang, Gauri Shadambikar, André S Bachmann

AAPS PharmSciTech· July 2025

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Monitoring ODC activity and polyamines in Bachmann-Bupp syndrome patient biological samples.
Chad R Schultz, Elizabeth A VanSickle, Caleb P Bupp, André S Bachmann

Methods Enzymol· May 2025

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Collection, preparation, and biobanking of clinical specimens for analysis in polyaminopathies.
Elizabeth A VanSickle, Chad R Schultz, André S Bachmann, Caleb P Bupp

Methods Enzymol· May 2025

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Novel LC-MS/MS assay to quantify D,L-alpha-difluoromethylornithine (DFMO) in mouse plasma.
Matthew A Swanson, Carlye Szarowicz, Schuyler T Pike, Chad R Schultz, André S Bachmann

Methods Enzymol· May 2025

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Repurposing With Purpose: Treatment of Bachmann-Bupp Syndrome With Eflornithine and Implications for Other Polyaminopathies.
Caleb P Bupp, Elizabeth A VanSickle, Julianne Michael, Chad R Schultz, Kelly Nguyen, André S Bachmann

Am J Med Genet C Semin Med Genet· April 2025

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Antitumor Activity of Allicin in a Pediatric Neuroblastoma Patient-derived Xenograft (PDX) Mouse Model.
Chad R Schultz, Martin C H Gruhlke, Alan J Slusarenko, André S Bachmann

In Vivo· April 2025

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Design, Synthesis, and Biological Activity of Novel Ornithine Decarboxylase (ODC) Inhibitors.
Chad R Schultz, Bilal Aleiwi, X Edward Zhou, Kelly Suino-Powell, Karsten Melcher, André S Bachmann

J Med Chem· March 2025

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Bachmann-Bupp syndrome and treatment.
André S Bachmann, Elizabeth A VanSickle, Julianne Michael, Marlie Vipond, Caleb P Bupp

Dev Med Child Neurol· April 2024

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Two New Cases of Bachmann-Bupp Syndrome Identified through the International Center for Polyamine Disorders.
Julianne Michael, Elizabeth VanSickle, Marlie Vipond, Abby Dalman, Jeremy Prokop, André S Bachmann

Med Sci (Basel)· April 2023

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New K50R mutant mouse models reveal impaired hypusination of eif5a2 with alterations in cell metabolite landscape.
Chad R Schultz, Ryan D Sheldon, Huirong Xie, Elena Y Demireva, Katie L Uhl, André S Bachmann

Biol Open· March 2023

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Synthesis and evaluation of small molecule inhibitors of LSD1 for use against MYCN-expressing neuroblastoma.
Catherine M Mills, Jonathan Turner, Ivett C Piña, Kathleen A Garrabrant, Dirk Geerts, André S Bachmann

Eur J Med Chem· December 2022

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Structure and Enzymatic Activity of an Intellectual Disability-Associated Ornithine Decarboxylase Variant, G84R.
X Edward Zhou, Chad R Schultz, Kelly Suino Powell, Amy Henrickson, Jared Lamp, André S Bachmann

ACS Omega· September 2022

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Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer.
Hong Im Kim, Chad R Schultz, Gadisetti V R Chandramouli, Dirk Geerts, John I Risinger, André S Bachmann

J Drug Target· July 2022

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Combined Plasma and Urinary Metabolomics Uncover Metabolic Perturbations Associated with Severe Respiratory Syncytial Viral Infection and Future Development of Asthma in Infant Patients.
Shao Thing Teoh, Mara L Leimanis-Laurens, Sarah S Comstock, John W Winters, Nikita L Vandenbosch, André S Bachmann

Metabolites· February 2022

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Structural basis of binding and inhibition of ornithine decarboxylase by 1-amino-oxy-3-aminopropane.
X Edward Zhou, Kelly Suino-Powell, Chad R Schultz, Bilal Aleiwi, Joseph S Brunzelle, André S Bachmann

Biochem J· December 2021

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Expanding the phenotype: Four new cases and hope for treatment in Bachmann-Bupp syndrome.
Elizabeth A VanSickle, Julianne Michael, André S Bachmann, Surender Rajasekaran, Jeremy W Prokop

Am J Med Genet A· November 2021

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Probenecid increases renal retention and antitumor activity of DFMO in neuroblastoma.
Chad R Schultz, Matthew A Swanson, Thomas C Dowling, André S Bachmann

Cancer Chemother Pharmacol· October 2021

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Selective targeting of CD38 hydrolase and cyclase activity as an approach to immunostimulation.
Thomas Z Benton, Catherine M Mills, Jonathan M Turner, Megan J Francis, Dalan J Solomon, André S Bachmann

RSC Adv· October 2021

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Repurposing eflornithine to treat a patient with a rare ODC1 gain-of-function variant disease.
Surender Rajasekaran, Caleb P Bupp, Mara Leimanis-Laurens, Ankit Shukla, Christopher Russell, André S Bachmann

Elife· July 2021

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Balancing precision versus cohort transcriptomic analysis of acute and recovery phase of viral bronchiolitis.
Ruchir Gupta, Mara L Leimanis, Marie Adams, André S Bachmann, Katie L Uhl

Am J Physiol Lung Cell Mol Physiol· June 2021

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Gene expression signatures identify paediatric patients with multiple organ dysfunction who require advanced life support in the intensive care unit.
Rama Shankar, Mara L Leimanis, Patrick A Newbury, Ke Liu, Jing Xing, André S Bachmann

EBioMedicine· December 2020

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Allicin, a Potent New Ornithine Decarboxylase Inhibitor in Neuroblastoma Cells.
Chad R Schultz, Martin C H Gruhlke, Alan J Slusarenko, André S Bachmann

J Nat Prod· August 2020

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