Publications by authors named "Ryan D Sheldon"

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Gut microbiome-derived tryptophan metabolites predict relapse in alcohol use disorder.
Cameron Forton, Jack DeVries, Miles Lou, Samuel Brundin, Tyce Cave, Ryan D Sheldon

Brain Behav Immun· January 2026

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Corrigendum to "Gut microbiome-derived tryptophan metabolites predict relapse in alcohol use disorder".
Cameron Forton, Jack DeVries, Miles Lou, Samuel Brundin, Tyce Cave, Ryan D Sheldon

Brain Behav Immun· January 2026

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Nutrient allocation fuels T cell-mediated immunity.
Joseph Longo, McLane J Watson, Kelsey S Williams, Ryan D Sheldon, Russell G Jones

Cell Metab· December 2025

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Dietary restriction reprograms CD8 T cell fate to enhance anti-tumour immunity and immunotherapy responses.
Brandon M Oswald, Lisa M DeCamp, Joseph Longo, Michael S Dahabieh, Nicholas Bunda, Ryan D Sheldon

Nat Metab· December 2025

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Interprotomer communication and functional asymmetry in H/ACA snoRNPs.
Hemendra Singh Panwar, Timothy J Vos, Xiaoyan Xie, H Josh Jang, Hyoungjoo Lee, Ryan D Sheldon

Proc Natl Acad Sci U S A· December 2025

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A noncanonical polyamine from bacteria antagonizes host mitochondrial function.
Kelsie M Nauta, Darrick R Gates, Matthew Weiland, Marco E Mechan-Llontop, Xiao Wang, Ryan D Sheldon

Nat Commun· November 2025

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Resolving early embryonic metabolism in Drosophila through single-embryo metabolomics and transcriptomics.
J Eduardo Pérez-Mojica, Zachary B Madaj, Christine Isaguirre, Joe Roy, Kin H Lau, Ryan D Sheldon

Nat Metab· October 2025

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An alternative route for β-hydroxybutyrate metabolism supports cytosolic acetyl-CoA synthesis in cancer cells.
Faith C Kaluba, Thomas J Rogers, Yu-Jin Jeong, Rachel 'Rae' J House, Althea Waldhart, Ryan D Sheldon

Nat Metab· October 2025

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Glucose-dependent glycosphingolipid biosynthesis fuels CD8 T cell function and tumor control.
Joseph Longo, Lisa M DeCamp, Brandon M Oswald, Robert Teis, Alfredo Reyes-Oliveras, Ryan D Sheldon

Cell Metab· September 2025

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Nrf2 drives activation-driven expansion of CD4T cells by modulating glucose and glutamine metabolism.
Aprajita Tripathi, Debolina Dasgupta, Michael S Dahabieh, Rachel Griffard-Smith, Anil Pant, Ryan D Sheldon

Cell Rep· September 2025

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Sperm meet the elevated energy demands to attain fertilization competence by increasing flux through aldolase.
Sara Violante, Aye Kyaw, Lana Kouatli, Kaushik Paladugu, Lauren Apostolakis, Ryan D Sheldon

Proc Natl Acad Sci U S A· September 2025

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High Baseline Plasma Anthranilic Acid Predicts Remission Upon Acute-Series Ketamine Infusion for Treatment-Resistant Depression.
Stephen A Murata, Zachary B Madaj, Colt D Capan, Ryan D Sheldon, Rif S El-Mallakh

Biol Psychiatry Glob Open Sci· July 2025

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The prostacyclin receptor PTGIR is a NRF2-dependent regulator of CD8 T cell exhaustion.
Michael S Dahabieh, Lisa M DeCamp, Brandon M Oswald, Susan M Kitchen-Goosen, Zhen Fu, Ryan D Sheldon

Nat Immunol· July 2025

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Mitochondrial fatty acid synthesis and MECR regulate CD4+ T cell function and oxidative metabolism.
KayLee K Steiner, Arissa C Young, Andrew R Patterson, Ayaka Sugiura, McLane J Watson, Ryan D Sheldon

J Immunol· May 2025

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Sex differences in peripheral and central dysregulation of the kynurenine pathway in Parkinson's disease.
Leslie C Jellen, Martha L Escobar Galvis, Qiong Sha, Christine Isaguirre, Amy Johnson, Ryan D Sheldon

NPJ Parkinsons Dis· May 2025

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Polyamine quantitation by LC-MS using isobutyl chloroformate derivatives.
Christine Isaguirre, Megan Gendjar, Kelsie M Nauta, Nicholas O Burton, Ryan D Sheldon

Methods Enzymol· May 2025

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Sperm meet the elevated energy demands to attain fertilization competence by increasing flux through aldolase.
Sara Violante, Aye Kyaw, Lana Kouatli, Kaushik Paladugu, Lauren Apostolakis, Ryan D Sheldon

bioRxiv· April 2025

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Lipid availability influences ferroptosis sensitivity in cancer cells by regulating polyunsaturated fatty acid trafficking.
Kelly H Sokol, Cameron J Lee, Thomas J Rogers, Althea Waldhart, Abigail E Ellis, Ryan D Sheldon

Cell Chem Biol· March 2025

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Nutrient-driven histone code determines exhausted CD8 T cell fates.
Shixin Ma, Michael S Dahabieh, Thomas H Mann, Steven Zhao, Bryan McDonald, Ryan D Sheldon

Science· February 2025

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A hierarchical hepatic de novo lipogenesis substrate supply network utilizing pyruvate, acetate, and ketones.
Adam J Rauckhorst, Ryan D Sheldon, Daniel J Pape, Adnan Ahmed, Kelly C Falls-Hubert

Cell Metab· January 2025

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An alternative route for β-hydroxybutyrate metabolism supports fatty acid synthesis in cancer cells.
Faith C Kaluba, Thomas J Rogers, Yu-Jin Jeong, Althea Waldhart, Kelly H Sokol, Ryan D Sheldon

bioRxiv· November 2024

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Metabolomics and C labelled glucose tracing to identify carbon incorporation into aberrant cell membrane glycans in cancer.
Alfredo Reyes-Oliveras, Abigail E Ellis, Ryan D Sheldon, Brian Haab

Commun Biol· November 2024

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Dietary Restriction Enhances CD8 T Cell Ketolysis to Limit Exhaustion and Boost Anti-Tumor Immunity.
Brandon M Oswald, Lisa M DeCamp, Joseph Longo, Michael S Dahabieh, Nicholas Bunda, Ryan D Sheldon

bioRxiv· November 2024

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Glucose-dependent glycosphingolipid biosynthesis fuels CD8 T cell function and tumor control.
Joseph Longo, Lisa M DeCamp, Brandon M Oswald, Robert Teis, Alfredo Reyes-Oliveras, Ryan D Sheldon

bioRxiv· October 2024

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Functional overlap of inborn errors of immunity and metabolism genes defines T cell metabolic vulnerabilities.
Andrew R Patterson, Gabriel A Needle, Ayaka Sugiura, Erin Q Jennings, Channing Chi, Ryan D Sheldon

Sci Immunol· August 2024

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