Publications by authors named "Andrea Comba"

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Autophagy Upregulation in Mutant Isocitrate Dehydrogenase 1 (IDH1) Glioma Uncovers a Novel Therapeutic Target.
Felipe J Núñez, Kaushik Banerjee, Anzar A Mujeeb, Ava Mauser, Claire E Tronrud, Andrea Comba

Res Sq· September 2025

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Epigenetic Reprogramming of Autophagy Leads to Uncovering a Novel Therapeutic Target for Mutant IDH1 Astrocytomas.
Felipe J Núñez, Kaushik Banerjee, Anzar A Mujeeb, Ava Mauser, Claire E Tronrud, Andrea Comba

bioRxiv· June 2025

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H3.3-G34R Mutation-Mediated Epigenetic Reprogramming Leads to Enhanced Efficacy of Immune Stimulatory Gene Therapy in Diffuse Hemispheric Gliomas.
Maria B Garcia-Fabiani, Santiago Haase, Kaushik Banerjee, Ziwen Zhu, Brandon L McClellan, Andrea Comba

bioRxiv· February 2025

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Novel inhibitory effect of Omega-3 fatty acids regulating pancreatic cancer progression.
María I Garay, Tamara Mazo, Victoria Ferrero, Nelso N Barotto, Clarisa Lagares, Andrea Comba

Carcinogenesis· January 2025

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Cell and gene therapy in neuro-oncology.
Maria Luisa Varela, Andrea Comba, Syed M Faisal, Anna Argento, Jorge A Peña Aguelo

Handb Clin Neurol· September 2024

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Spatiotemporal Insights into Glioma Oncostream Dynamics: Unraveling Formation, Stability, and Disassembly Pathways.
Syed M Faisal, Jarred E Clewner, Brooklyn Stack, Maria L Varela, Andrea Comba

Adv Sci (Weinh)· May 2024

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Editorial: Brain cancer pathogenesis and data integration.
Andrea Comba, Xinzhong Li, Barbara Breznik

Front Genet· October 2023

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Combined cytotoxic and immune-stimulatory gene therapy for primary adult high-grade glioma: a phase 1, first-in-human trial.
Yoshie Umemura, Daniel Orringer, Larry Junck, Maria L Varela, Molly E J West, Andrea Comba

Lancet Oncol· September 2023

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Scale-free correlations and potential criticality in weakly ordered populations of brain cancer cells.
Kevin B Wood, Andrea Comba, Sebastien Motsch, Tomás S Grigera, Pedro R Lowenstein

Sci Adv· June 2023

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Generation of 3D ex vivo mouse- and patient-derived glioma explant slice model for integration of confocal time-lapse imaging and spatial analysis.
Andrea Comba, Maria Luisa Varela, Syed M Faisal, Clifford C Abel, Anna E Argento

STAR Protoc· March 2023

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Gene Therapy for High Grade Glioma: The Clinical Experience.
Maria Luisa Varela, Andrea Comba, Syed M Faisal, Anna Argento, Andrea Franson

Expert Opin Biol Ther· February 2023

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H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models.
Santiago Haase, Kaushik Banerjee, Anzar A Mujeeb, Carson S Hartlage, Fernando M Núñez, Andrea Comba

J Clin Invest· November 2022

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The complex interactions between the cellular and non-cellular components of the brain tumor microenvironmental landscape and their therapeutic implications.
Syed M Faisal, Andrea Comba, Maria L Varela, Anna E Argento, Emily Brumley

Front Oncol· October 2022

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Development of immunotherapy for high-grade gliomas: Overcoming the immunosuppressive tumor microenvironment.
Andrea Franson, Brandon L McClellan, Maria Luisa Varela, Andrea Comba, Mohammad Faisal Syed

Front Med (Lausanne)· September 2022

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Systemic Delivery of an Adjuvant CXCR4-CXCL12 Signaling Inhibitor Encapsulated in Synthetic Protein Nanoparticles for Glioma Immunotherapy.
Mahmoud S Alghamri, Kaushik Banerjee, Anzar A Mujeeb, Ava Mauser, Ayman Taher, Andrea Comba

ACS Nano· June 2022

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Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression.
Andrea Comba, Syed M Faisal, Patrick J Dunn, Anna E Argento, Todd C Hollon

Nat Commun· June 2022

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Erratum: Fyn tyrosine kinase, a downstream target of receptor tyrosine kinases, modulates antiglioma immune responses.
Andrea Comba, Patrick J Dunn, Anna E Argento, Padma Kadiyala, Maria Ventosa

Neuro Oncol· August 2021

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A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1.
Diana Shah, Andrea Comba, Syed M Faisal, Padma Kadiyala, Gregory J Baker

Oncoimmunology· August 2021

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Uncovering Spatiotemporal Heterogeneity of High-Grade Gliomas: From Disease Biology to Therapeutic Implications.
Andrea Comba, Syed M Faisal, Maria Luisa Varela, Todd Hollon, Wajd N Al-Holou

Front Oncol· August 2021

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Genetic Alterations in Gliomas Remodel the Tumor Immune Microenvironment and Impact Immune-Mediated Therapies.
Maria B Garcia-Fabiani, Santiago Haase, Andrea Comba, Stephen Carney, Brandon McClellan

Front Oncol· June 2021

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Isolation and characterization of immune cells from the tumor microenvironment of genetically engineered pediatric high-grade glioma models using the sleeping beauty transposon system.
Maria Belen Garcia-Fabiani, Andrea Comba, Padma Kadiyala, Santiago Haase, Felipe Javier Núñez

Methods Enzymol· December 2020

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Immunotherapy for gliomas: shedding light on progress in preclinical and clinical development.
Maria B Garcia-Fabiani, Maria Ventosa, Andrea Comba, Marianela Candolfi, Alejandro J Nicola Candia

Expert Opin Investig Drugs· July 2020

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Fyn tyrosine kinase, a downstream target of receptor tyrosine kinases, modulates antiglioma immune responses.
Andrea Comba, Patrick J Dunn, Anna E Argento, Padma Kadiyala, Maria Ventosa

Neuro Oncol· June 2020

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Self-organization in brain tumors: How cell morphology and cell density influence glioma pattern formation.
Sara Jamous, Andrea Comba, Pedro R Lowenstein, Sebastien Motsch

PLoS Comput Biol· May 2020

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Laser Capture Microdissection of Glioma Subregions for Spatial and Molecular Characterization of Intratumoral Heterogeneity, Oncostreams, and Invasion.
Andrea Comba, Patrick J Dunn, Phillip E Kish, Padma Kadiyala, Alon Kahana

J Vis Exp· April 2020

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