Publications by authors named "Andrea Griesinger"

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Multi-pronged analysis of pediatric low-grade glioma and ganglioglioma reveals a unique tumor microenvironment associated with BRAF alterations.
Shadi Zahedi, Kent Riemondy, Tian Liu, Andrea M Griesinger, Andrew M Donson

Brain Pathol· November 2025

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Loss of LDOC1 by chromatin compaction in mesenchymal tumor cells is required for PFA1 ependymoma growth.
Graziella Ribeiro de Sousa, Annaliese J Calzadilla, Enrique Grimaldo, Andrew M Donson, Lays Martin Sobral, Andrea M Griesinger

Neuro Oncol· July 2025

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Development of Chromosome 1q+ Specific Treatment for Highest Risk Pediatric Posterior Fossa Ependymoma.
Andrea M Griesinger, Annaliese J Calzadilla, Enrique Grimaldo, Andrew M Donson, Vladimir Amani

Clin Cancer Res· April 2024

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Multi-pronged analysis of pediatric low-grade glioma reveals a unique tumor microenvironment associated with BRAF alterations.
Shadi Zahedi, Kent Riemondy, Andrea M Griesinger, Andrew M Donson, Rui Fu

bioRxiv· April 2024

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Tumor and immune cell types interact to produce heterogeneous phenotypes of pediatric high-grade glioma.
John DeSisto, Andrew M Donson, Andrea M Griesinger, Rui Fu, Kent Riemondy

Neuro Oncol· March 2024

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Significant increase of high-risk chromosome 1q gain and 6q loss at recurrence in posterior fossa group A ependymoma: A multicenter study.
Andrew M Donson, Kelsey C Bertrand, Kent A Riemondy, Dexiang Gao, Yonghua Zhuang, Andrea M Griesinger

Neuro Oncol· October 2023

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Genetic predictors of neurocognitive outcomes in survivors of pediatric brain tumors.
Sydney T Grob, Kristen R Miller, Bridget Sanford, Andrew M Donson, Kenneth Jones, Andrea M Griesinger

J Neurooncol· October 2023

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Multi-omic approach identifies hypoxic tumor-associated myeloid cells that drive immunobiology of high-risk pediatric ependymoma.
Andrea M Griesinger, Kent Riemondy, Nithyashri Eswaran, Andrew M Donson, Nicholas Willard

iScience· September 2023

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Integration of single-nuclei RNA-sequencing, spatial transcriptomics and histochemistry defines the complex microenvironment of NF1-associated plexiform neurofibromas.
Vladimir Amani, Kent A Riemondy, Rui Fu, Andrea M Griesinger, Enrique Grimaldo

Acta Neuropathol Commun· September 2023

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Cellular Therapy for Children with Central Nervous System Tumors: Mining and Mapping the Correlative Data.
Erin E Crotty, Ashley L Wilson, Tom Davidson, Sophia Tahiri, Juliane Gust, Andrea M Griesinger

Curr Oncol Rep· August 2023

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Genetic Predictors of Neurocognitive Outcomes in Survivors of Pediatric Brain Tumors.
Sydney T Grob, Kristen R Miller, Bridget Sanford, Andrew M Donson, Kenneth Jones, Andrea M Griesinger

Res Sq· August 2023

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Spatial transcriptomic analysis delineates epithelial and mesenchymal subpopulations and transition stages in childhood ependymoma.
Rui Fu, Gregory A Norris, Nicholas Willard, Andrea M Griesinger, Kent A Riemondy

Neuro Oncol· April 2023

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Neoplastic and immune single-cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma.
Kent A Riemondy, Sujatha Venkataraman, Nicholas Willard, Anandani Nellan, Bridget Sanford, Andrea M Griesinger

Neuro Oncol· February 2022

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Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas.
Pooja Panwalkar, Benita Tamrazi, Derek Dang, Chan Chung, Stefan Sweha, Andrea M Griesinger

Sci Transl Med· October 2021

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Single-Cell RNA Sequencing of Childhood Ependymoma Reveals Neoplastic Cell Subpopulations That Impact Molecular Classification and Etiology.
Austin E Gillen, Kent A Riemondy, Vladimir Amani, Andrea M Griesinger, Ahmed Gilani

Cell Rep· August 2020

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Targeting MYC-driven replication stress in medulloblastoma with AZD1775 and gemcitabine.
Daniel C Moreira, Sujatha Venkataraman, Apurva Subramanian, John Desisto, Ilango Balakrishnan, Andrea Griesinger

J Neurooncol· May 2020

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Establishment of patient-derived orthotopic xenograft model of 1q+ posterior fossa group A ependymoma.
Angela M Pierce, Davis A Witt, Andrew M Donson, Ahmed Gilani, Bridget Sanford, Andrea M Griesinger

Neuro Oncol· December 2019

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Inhibition of MYC attenuates tumor cell self-renewal and promotes senescence in SMARCB1-deficient Group 2 atypical teratoid rhabdoid tumors to suppress tumor growth in vivo.
Irina Alimova, Angela Pierce, Etienne Danis, Andrew Donson, Diane K Birks, Andrea Griesinger

Int J Cancer· April 2019

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Identification of FDA-Approved Oncology Drugs with Selective Potency in High-Risk Childhood Ependymoma.
Andrew M Donson, Vladimir Amani, Elliot A Warner, Andrea M Griesinger, Davis A Witt

Mol Cancer Ther· September 2018

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Specific expression of PD-L1 in RELA-fusion supratentorial ependymoma: Implications for PD-1-targeted therapy.
Davis A Witt, Andrew M Donson, Vladimir Amani, Daniel C Moreira, Bridget Sanford, Andrea M Griesinger

Pediatr Blood Cancer· May 2018

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Durable regression of Medulloblastoma after regional and intravenous delivery of anti-HER2 chimeric antigen receptor T cells.
Anandani Nellan, Christopher Rota, Robbie Majzner, Cynthia M Lester-McCully, Andrea M Griesinger

J Immunother Cancer· April 2018

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NF-κB upregulation through epigenetic silencing of LDOC1 drives tumor biology and specific immunophenotype in Group A ependymoma.
Andrea M Griesinger, Davis A Witt, Sydney T Grob, Sabrina R Georgio Westover, Andrew M Donson

Neuro Oncol· October 2017

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Molecular Analyses Reveal Inflammatory Mediators in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma.
Andrew M Donson, John Apps, Andrea M Griesinger, Vladimir Amani, Davis A Witt

J Neuropathol Exp Neurol· September 2017

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Characterization of 2 Novel Ependymoma Cell Lines With Chromosome 1q Gain Derived From Posterior Fossa Tumors of Childhood.
Vladimir Amani, Andrew M Donson, Seth C Lummus, Eric W Prince, Andrea M Griesinger

J Neuropathol Exp Neurol· July 2017

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Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors.
Jean M Mulcahy Levy, Shadi Zahedi, Andrea M Griesinger, Andrew Morin, Kurtis D Davies

Elife· January 2017

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