Publications by authors named "Andrea Mattevi"

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Myeloperoxidase: one enzyme, two jobs.
Sara Marchese, Andrea Mattevi

Cell Res· November 2025

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Uncovering a Mutation-Independent Therapeutic Strategy against Inherited Retinal Diseases: Development of Class I HDAC/LSD1 Hybrid Inhibitors.
Gabriele Carullo, Ilaria Piano, Giulia Salamone, Francesca Corsi, Noemi Orsini, Andrea Mattevi

ACS Chem Neurosci· September 2025

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Tranylcypromine-Based LSD1 Inhibitors as Useful Agents to Reduce Viability of .
Emanuele Fabbrizi, Gebremedhin Solomon Hailu, A Ganesan, Rossella Fioravanti, Clemens Zwergel, Andrea Mattevi

ACS Infect Dis· August 2025

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Enhancing Selectivity and Potency of SAr Covalent Inhibitors of NADPH Oxidase Enzymes.
Blessing C Ogboo, Kishan B Patel, Marta Massari, Sara Marchese, Joana Reis, Andrea Mattevi

J Med Chem· July 2025

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Complete Enzyme Clustering Enhances Coenzyme Q Biosynthesis via Substrate Channeling.
Dianzhuo Wang, Andrea Gottinger, Jio Jeong, Callum R Nicoll, Junlang Liu, Andrea Mattevi

bioRxiv· May 2025

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Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance.
Amanda L Waterbury, Jonatan Caroli, Olivia Zhang, Paloma R Tuttle, Chao Liu, Andrea Mattevi

Nat Commun· April 2025

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Kinetic and structural investigation of the 4-allyl syringol oxidase from Streptomyces cavernae.
Daniel Eggerichs, Heiner G Weddeling, Laura Alvigini, Tobias Rapsch, Nils Weindorf, Andrea Mattevi

Arch Biochem Biophys· March 2025

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UM171 glues asymmetric CRL3-HDAC1/2 assembly to degrade CoREST corepressors.
Megan J R Yeo, Olivia Zhang, Xiaowen Xie, Eunju Nam, N Connor Payne, Andrea Mattevi

Nature· March 2025

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Design of Benzyl-triazolopyrimidine-Based NADPH Oxidase Inhibitors Leads to the Discovery of a Potent Dual Covalent NOX2/MAOB Inhibitor.
Beatrice Noce, Sara Marchese, Marta Massari, Chiara Lambona, Joana Reis, Andrea Mattevi

J Med Chem· March 2025

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Structural and Mechanistic Characterization of the Flavin-Dependent Monooxygenase and Oxidase Involved in Sorbicillinoid Biosynthesis.
Gwen Tjallinks, Nicolò Angeleri, Quoc-Thai Nguyen, Barbara Mannucci, Mark Arentshorst, Andrea Mattevi

ACS Chem Biol· March 2025

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Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1.
Kwangwoon Lee, Marco Barone, Amanda L Waterbury, Hanjie Jiang, Eunju Nam, Andrea Mattevi

Nat Chem Biol· February 2025

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Biochemical and structural insights into pinoresinol hydroxylase from Pseudomonas sp.
Teresa Benedetta Guerriere, Marco W Fraaije, Andrea Mattevi

Arch Biochem Biophys· February 2025

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Dehydrogenase oxidase function: the interplay between substrate binding and flavin microenvironment.
Teresa Benedetta Guerriere, Alessandro Vancheri, Ilaria Ricotti, Stefano A Serapian, Daniel Eggerichs, Andrea Mattevi

ACS Catal· January 2025

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Discovery and biochemical characterization of thermostable glycerol oxidases.
Lars L Santema, Laura Rotilio, Ruite Xiang, Gwen Tjallinks, Victor Guallar, Andrea Mattevi

Appl Microbiol Biotechnol· December 2024

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Evolution, structure, and drug-metabolizing activity of mammalian prenylcysteine oxidases.
Marco Barone, Letizia Pizzorni, Marco W Fraaije, Maria L Mascotti, Andrea Mattevi

J Biol Chem· November 2024

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Biosynthetic Strategies of Berberine Bridge Enzyme-like Flavoprotein Oxidases toward Structural Diversification in Natural Product Biosynthesis.
Gwen Tjallinks, Andrea Mattevi, Marco W Fraaije

Biochemistry· September 2024

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The scaffolding function of LSD1 controls DNA methylation in mouse ESCs.
Sandhya Malla, Kanchan Kumari, Carlos A García-Prieto, Jonatan Caroli, Anna Nordin, Andrea Mattevi

Nat Commun· September 2024

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Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical models.
Sumer Jasmine, Adel Mandl, Timothy E G Krueger, Susan L Dalrymple, Lizamma Antony, Andrea Mattevi

Prostate· July 2024

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Structure, mechanism, and evolution of the last step in vitamin C biosynthesis.
Alessandro Boverio, Neelam Jamil, Barbara Mannucci, Maria Laura Mascotti, Marco W Fraaije, Andrea Mattevi

Nat Commun· May 2024

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Asymmetric Engagement of Dimeric CRL3 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes.
Megan Jr Yeo, Olivia Zhang, Xiaowen Xie, Eunju Nam, Neil Connor Payne, Andrea Mattevi

bioRxiv· May 2024

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In vitro construction of the COQ metabolon unveils the molecular determinants of coenzyme Q biosynthesis.
Callum R Nicoll, Laura Alvigini, Andrea Gottinger, Domiziana Cecchini, Barbara Mannucci, Andrea Mattevi

Nat Catal· January 2024

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Efficient Oxidation of 5-Hydroxymethylfurfural Using a Flavoprotein Oxidase from the Honeybee Apis mellifera.
Gwen Tjallinks, Alessandro Boverio, Amarins W Jager, Saniye G Kaya, Andrea Mattevi

Chembiochem· December 2023

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Targeting ROS production through inhibition of NADPH oxidases.
Joana Reis, Christoph Gorgulla, Marta Massari, Sara Marchese, Sergio Valente, Andrea Mattevi

Nat Chem Biol· December 2023

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One-Pot Biocatalytic Synthesis of -Syringaresinol from a Lignin-Derived Phenol.
Yiming Guo, Laura Alvigini, Mohammad Saifuddin, Ben Ashley, Milos Trajkovic, Andrea Mattevi

ACS Catal· November 2023

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The NPAC-LSD2 complex in nucleosome demethylation.
Jonatan Caroli, Andrea Mattevi

Enzymes· October 2023

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