Publications by authors named "Andrea Strasser"

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Shining light on the histamine H receptor: Synthesis of carbamoylguanidine-type agonists as a pharmacological tool to study internalization.
Katharina Tropmann, Ulla Seibel-Ehlert, Timo Littmann, Andrea Strasser

Bioorg Med Chem Lett· November 2021

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Label-Free Investigations on the G Protein Dependent Signaling Pathways of Histamine Receptors.
Ulla Seibel-Ehlert, Nicole Plank, Asuka Inoue, Guenther Bernhardt, Andrea Strasser

Int J Mol Sci· September 2021

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Specific Engineered G Protein Coupling to Histamine Receptors Revealed from Cellular Assay Experiments and Accelerated Molecular Dynamics Simulations.
Carina Höring, Marcus Conrad, Christian A Söldner, Jinan Wang, Heinrich Sticht, Andrea Strasser

Int J Mol Sci· September 2021

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Abolishing Dopamine D/D Receptor Affinity of Subtype-Selective Carbamoylguanidine-Type Histamine H Receptor Agonists.
Katharina Tropmann, Merlin Bresinsky, Lisa Forster, Denise Mönnich, Armin Buschauer, Andrea Strasser

J Med Chem· June 2021

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A Dynamic, Split-Luciferase-Based Mini-G Protein Sensor to Functionally Characterize Ligands at All Four Histamine Receptor Subtypes.
Carina Höring, Ulla Seibel, Katharina Tropmann, Lukas Grätz, Denise Mönnich, Andrea Strasser

Int J Mol Sci· November 2020

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Structure-Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles.
Dominik Dolles, Matthias Hoffmann, Sandra Gunesch, Oliviero Marinelli, Jan Möller, Andrea Strasser

J Med Chem· February 2018

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Molecular Modelling Approaches for the Analysis of Histamine Receptors and Their Interaction with Ligands.
Andrea Strasser, Hans-Joachim Wittmann

Handb Exp Pharmacol· October 2017

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Binding Kinetics and Pathways of Ligands to GPCRs.
Andrea Strasser, Hans-Joachim Wittmann, Roland Seifert

Trends Pharmacol Sci· August 2017

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Competitive association binding kinetic assays: a new tool to detect two different binding orientations of a ligand to its target protein under distinct conditions?
Hans-Joachim Wittmann, Andrea Strasser

Naunyn Schmiedebergs Arch Pharmacol· June 2017

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Dibenzo[b,f][1,4]oxazepines and dibenzo[b,e]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the HR, HR, 5-HTR and other selected GPCRs.
Franziska Naporra, Susanne Gobleder, Hans-Joachim Wittmann, Julia Spindler, Michael Bodensteiner, Andrea Strasser

Pharmacol Res· November 2016

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Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors and hCB2 R Ligands To Combat Neurodegenerative Disorders.
Dominik Dolles, Martin Nimczick, Matthias Scheiner, Jacqueline Ramler, Patricia Stadtmüller, Andrea Strasser

ChemMedChem· June 2016

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Conformational Restriction and Enantioseparation Increase Potency and Selectivity of Cyanoguanidine-Type Histamine H4 Receptor Agonists.
Roland Geyer, Uwe Nordemann, Andrea Strasser, Hans-Joachim Wittmann, Armin Buschauer

J Med Chem· April 2016

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2,4-Diaminopyrimidines as dual ligands at the histamine H1 and H4 receptor-H1/H4-receptor selectivity.
Sebastian G Hammer, Susanne Gobleder, Franziska Naporra, Hans-Joachim Wittmann, Sigurd Elz, Andrea Strasser

Bioorg Med Chem Lett· January 2016

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Structure-Dependent Deconjugation of Flavonoid Glucuronides by Human β-Glucuronidase - In Vitro and In Silico Analyses.
Monika Untergehrer, Daniel Bücherl, Hans-Joachim Wittmann, Andrea Strasser, Jörg Heilmann

Planta Med· August 2015

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Modulation of GPCRs by monovalent cations and anions.
Andrea Strasser, Hans-Joachim Wittmann, Erich H Schneider, Roland Seifert

Naunyn Schmiedebergs Arch Pharmacol· March 2015

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Binding pathway of histamine to the hH4R, observed by unconstrained molecular dynamics.
Hans-Joachim Wittmann, Andrea Strasser

Bioorg Med Chem Lett· March 2015

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New insights into the cross-linking and degradation mechanism of Diels-Alder hydrogels.
Susanne Kirchhof, Andrea Strasser, Hans-Joachim Wittmann, Viktoria Messmann, Nadine Hammer

J Mater Chem B· January 2015

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Mathematical analysis of the sodium sensitivity of the human histamine H3 receptor.
Hans-Joachim Wittmann, Roland Seifert, Andrea Strasser

In Silico Pharmacol· December 2014

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Loratadine and analogues: discovery and preliminary structure-activity relationship of inhibitors of the amino acid transporter B(0)AT2.
Serena Cuboni, Christian Devigny, Bastiaan Hoogeland, Andrea Strasser, Sebastian Pomplun

J Med Chem· November 2014

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Sodium binding to hH3R and hH 4R--a molecular modeling study.
Hans-Joachim Wittmann, Roland Seifert, Andrea Strasser

J Mol Model· August 2014

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Pharmacological profile of astemizole-derived compounds at the histamine H1 and H4 receptor--H1/H4 receptor selectivity.
Eva Wagner, Hans-Joachim Wittmann, Sigurd Elz, Andrea Strasser

Naunyn Schmiedebergs Arch Pharmacol· March 2014

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Synthesis, biological evaluation, and computational studies of Tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists.
Fouad H Darras, Steffen Pockes, Guozheng Huang, Sarah Wehle, Andrea Strasser

ACS Chem Neurosci· March 2014

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Molecular modeling studies give hint for the existence of a symmetric hβ₂R-Gαβγ-homodimer.
Andrea Straßer, Hans-Joachim Wittmann

J Mol Model· October 2013

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Lysis matters: red cell lysis with FACS Lyse affects the flow cytometric enumeration of circulating leukemic blasts.
Elisa Einwallner, Almira Subasic, Andrea Strasser, Dorothea Augustin, Renate Thalhammer

J Immunol Methods· April 2013

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Molecular and cellular analysis of human histamine receptor subtypes.
Roland Seifert, Andrea Strasser, Erich H Schneider, Detlef Neumann, Stefan Dove

Trends Pharmacol Sci· January 2013

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