Publications by authors named "Andreas Plaitakis"

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Isolated Non-Progressive Hemidystonia in a Patient Homozygous for H63D Variant of Hereditary Hemochromatosis: A Case Report and Systematic Literature Review of Movement Disorders in Hereditary Hemochromatosis.
Stefania Kalampokini, Andreas Plaitakis, Cleanthe Spanaki, Georgia Xiromerisiou

Diagnostics (Basel)· September 2025

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Evolution of Glutamate Metabolism via Enhances Lactate-Dependent Synaptic Plasticity and Complex Cognition.
Andreas Plaitakis, Kyriaki Sidiropoulou, Dimitra Kotzamani, Ionela Litso, Ioannis Zaganas

Int J Mol Sci· May 2024

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Glutamate-specific gene linked to human brain evolution enhances synaptic plasticity and cognitive processes.
Cleanthe Spanaki, Kyriaki Sidiropoulou, Zoe Petraki, Konstantinos Diskos, Xanthippi Konstantoudaki, Andreas Plaitakis

iScience· February 2024

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Structural Evolution of Primate Glutamate Dehydrogenase 2 as Revealed by In Silico Predictions and Experimentally Determined Structures.
Ionela Litso, Andreas Plaitakis, Vasiliki E Fadouloglou, Mary Providaki, Michael Kokkinidis

Biomolecules· December 2023

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Study of Alzheimer's disease- and frontotemporal dementia-associated genes in the Cretan Aging Cohort.
Lambros Mathioudakis, Christina Dimovasili, Mara Bourbouli, Helen Latsoudis, Evgenia Kokosali, Andreas Plaitakis

Neurobiol Aging· March 2023

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High Hereditary Transthyretin-Related Amyloidosis Prevalence in Crete: Genetic Heterogeneity and Distinct Phenotypes.
Minas Tzagournissakis, Emmanouil Foukarakis, Dimitrios Samonakis, Miltiadis Tsilimbaris, Kleita Michaelidou, Andreas Plaitakis

Neurol Genet· October 2022

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Crystal structure of glutamate dehydrogenase 2, a positively selected novel human enzyme involved in brain biology and cancer pathophysiology.
Christina Dimovasili, Vasiliki E Fadouloglou, Aikaterini Kefala, Mary Providaki, Dina Kotsifaki, Andreas Plaitakis

J Neurochem· May 2021

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Transgenic expression of the positive selected human GLUD2 gene improves in vivo glucose homeostasis by regulating basic insulin secretion.
Zoe Petraki, Stavros Droubogiannis, Konstantina Mylonaki, Gregory Chlouverakis, Andreas Plaitakis

Metabolism· November 2019

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The Cretan Aging Cohort: Cohort Description and Burden of Dementia and Mild Cognitive Impairment.
Ioannis V Zaganas, Panagiotis Simos, Maria Basta, Stefania Kapetanaki, Symeon Panagiotakis, Andreas Plaitakis

Am J Alzheimers Dis Other Demen· February 2019

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Transgenic Mice Carrying GLUD2 as a Tool for Studying the Expressional and the Functional Adaptation of this Positive Selected Gene in Human Brain Evolution.
Andreas Plaitakis, Dimitra Kotzamani, Zoe Petraki, Maria Delidaki, Vagelis Rinotas

Neurochem Res· January 2019

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The Glutamate Dehydrogenase Pathway and Its Roles in Cell and Tissue Biology in Health and Disease.
Andreas Plaitakis, Ester Kalef-Ezra, Dimitra Kotzamani, Ioannis Zaganas, Cleanthe Spanaki

Biology (Basel)· February 2017

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Widening Spectrum of Cellular and Subcellular Expression of Human GLUD1 and GLUD2 Glutamate Dehydrogenases Suggests Novel Functions.
Cleanthe Spanaki, Dimitra Kotzamani, Andreas Plaitakis

Neurochem Res· January 2017

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Evolution of GLUD2 Glutamate Dehydrogenase Allows Expression in Human Cortical Neurons.
Cleanthe Spanaki, Dimitra Kotzamani, Kleopas Kleopa, Andreas Plaitakis

Mol Neurobiol· October 2016

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Import of a major mitochondrial enzyme depends on synergy between two distinct helices of its presequence.
Ester Kalef-Ezra, Dimitra Kotzamani, Ioannis Zaganas, Nitsa Katrakili, Andreas Plaitakis

Biochem J· September 2016

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Expression of human GLUD1 and GLUD2 glutamate dehydrogenases in steroid producing tissues.
Cleanthe Spanaki, Dimitra Kotzamani, Zoe Petraki, Elias Drakos, Andreas Plaitakis

Mol Cell Endocrinol· November 2015

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Differential interaction of hGDH1 and hGDH2 with manganese: Implications for metabolism and toxicity.
Christina Dimovasili, Michael Aschner, Andreas Plaitakis, Ioannis Zaganas

Neurochem Int· September 2015

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Side-chain interactions in the regulatory domain of human glutamate dehydrogenase determine basal activity and regulation.
Vasileios Mastorodemos, Konstantinos Kanavouras, Shobana Sundaram, Maria Providaki, Zoe Petraki, Andreas Plaitakis

J Neurochem· April 2015

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Regional MRI perfusion measures predict motor/executive function in patients with clinically isolated syndrome.
Efrosini Z Papadaki, Panagiotis G Simos, Vasileios C Mastorodemos, Theodora Panou, Thomas G Maris, Andreas Plaitakis

Behav Neurol· December 2014

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Glutamate dehydrogenase isoforms with N-terminal (His)6- or FLAG-tag retain their kinetic properties and cellular localization.
Kamilla Pajęcka, Camilla Wendel Nielsen, Anne Hauge, Ioannis Zaganas, Lasse K Bak, Andreas Plaitakis

Neurochem Res· November 2014

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The discovery of human of GLUD2 glutamate dehydrogenase and its implications for cell function in health and disease.
Pullanipally Shashidharan, Andreas Plaitakis

Neurochem Res· November 2014

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Heterogeneous cellular distribution of glutamate dehydrogenase in brain and in non-neural tissues.
Cleanthe Spanaki, Dimitra Kotzamani, Zoe Petraki, Elias Drakos, Andreas Plaitakis

Neurochem Res· November 2014

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Coexistence of systemic lupus erythematosus and multiple sclerosis: prevalence, clinical characteristics, and natural history.
Antonis Fanouriakis, Vasileios Mastorodemos, Cristina Pamfil, Efrosini Papadaki, Prodromos Sidiropoulos, Andreas Plaitakis

Semin Arthritis Rheum· June 2014

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Assessment of Parkinson's disease risk loci in Greece.
Eleanna Kara, Georgia Xiromerisiou, Cleanthe Spanaki, Maria Bozi, Georgios Koutsis, Andreas Plaitakis

Neurobiol Aging· February 2014

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Hsf-1 affects podocyte markers NPHS1, NPHS2 and WT1 in a transgenic mouse model of TTRVal30Met-related amyloidosis.
Ioannis Petrakis, Vasiliki Mavroeidi, Kostas Stylianou, Eva Andronikidi, Eirini Lioudaki, Andreas Plaitakis

Amyloid· September 2013

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Deregulation of glutamate dehydrogenase in human neurologic disorders.
Andreas Plaitakis, Ioannis Zaganas, Cleanthe Spanaki

J Neurosci Res· August 2013

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