Publications by authors named "Andrei Bakin"

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BOGO: A Proteome-Wide Gene Overexpression Platform for Discovering Rational Cancer Combination Therapies.
Kyeong Beom Jo, Mohammed M Alruwaili, Da-Eun Kim, Yongjun Koh, Hyeyeon Kim, Andrei V Bakin

bioRxiv· November 2025

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A Sequential Triple-Drug Strategy for Selective Targeting of p53-Mutant Cancers.
Mohammed M Alruwaili, Yanqi Guo, Justin Zonneville, Thomas Melendy, Robert M Straubinger, Andrei V Bakin

bioRxiv· November 2025

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p38 blockade reverses the immune suppressive tumor microenvironment in metastatic breast cancer.
Priyanka Rajan, Robert Zollo, Yanqi Guo, Mohammed Alruwaili, Justin Zonneville, Andrei V Bakin

Res Sq· October 2025

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p38 blockade reverses the immune suppressive tumor microenvironment in metastatic breast cancer.
Priyanka Rajan, Robert Zollo, Yanqi Guo, Mohammed Alruwaili, Justin Zonneville, Andrei V Bakin

bioRxiv· May 2025

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TAS-102, Irinotecan, and bevacizumab in pre-treated metastatic colorectal cancer (TABAsCO), a phase II clinical trial.
Patrick M Boland, Sarbajit Mukherjee, Iman Imanirad, Namrata Vijayvergia, Seth D Cohen, Andrei Bakin

Br J Cancer· November 2024

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A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers.
Mohammed M Alruwaili, Justin Zonneville, Maricris N Naranjo, Hannah Serio, Thomas Melendy, Andrei V Bakin

Cell Rep Med· March 2024

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Dissection of a Down syndrome-associated trisomy to separate the gene dosage-dependent and -independent effects of an extra chromosome.
Zhuo Xing, Yichen Li, Eduardo Cortes-Gomez, Xiaoling Jiang, Shuang Gao, Andrei V Bakin

Hum Mol Genet· June 2023

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WEE1 inhibition augments CDC7 (DDK) inhibitor-induced cell death in Ewing sarcoma by forcing premature mitotic entry and mitotic catastrophe.
Jeffrey C Martin, Jennie R Sims, Ajay Gupta, Andrei V Bakin, Joyce E Ohm

Cancer Res Commun· June 2022

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Selective therapeutic strategy for p53-deficient cancer by targeting dysregulation in DNA repair.
Justin Zonneville, Moyi Wang, Mohammed M Alruwaili, Brandon Smith, Megan Melnick, Andrei V Bakin

Commun Biol· July 2021

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Blockade of p38 kinase impedes the mobilization of protumorigenic myeloid populations to impact breast cancer metastasis.
Justin Zonneville, Sean Colligan, Sydney Grant, Alexandra Miller, Paul Wallace, Andrei V Bakin

Int J Cancer· October 2020

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TAK1 signaling regulates p53 through a mechanism involving ribosomal stress.
Justin Zonneville, Vincent Wong, Michelle Limoge, Mikhail Nikiforov, Andrei V Bakin

Sci Rep· February 2020

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XBP1-KLF9 Axis Acts as a Molecular Rheostat to Control the Transition from Adaptive to Cytotoxic Unfolded Protein Response.
Emily E Fink, Sudha Moparthy, Archis Bagati, Anna Bianchi-Smiraglia, Brittany C Lipchick, Andrei V Bakin

Cell Rep· October 2018

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TGF-β signaling promotes tumor vasculature by enhancing the pericyte-endothelium association.
Justin Zonneville, Alfiya Safina, Alexander M Truskinovsky, Carlos L Arteaga, Andrei V Bakin

BMC Cancer· June 2018

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Triplications of human chromosome 21 orthologous regions in mice result in expansion of megakaryocyte-erythroid progenitors and reduction of granulocyte-macrophage progenitors.
Chunhong Liu, Tao Yu, Zhuo Xing, Xiaoling Jiang, Yichen Li, Andrei V Bakin

Oncotarget· January 2018

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Internally ratiometric fluorescent sensors for evaluation of intracellular GTP levels and distribution.
Anna Bianchi-Smiraglia, Mitra S Rana, Colleen E Foley, Leslie M Paul, Brittany C Lipchick, Andrei V Bakin

Nat Methods· October 2017

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Tumor p38MAPK signaling enhances breast carcinoma vascularization and growth by promoting expression and deposition of pro-tumorigenic factors.
Michelle Limoge, Alfiya Safina, Alexander M Truskinovsky, Ieman Aljahdali, Justin Zonneville, Andrei V Bakin

Oncotarget· September 2017

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Tumor-fibroblast interactions stimulate tumor vascularization by enhancing cytokine-driven production of MMP9 by tumor cells.
Michelle Limoge, Alfiya Safina, Amy Beattie, Lauren Kapus, Alexander M Truskinovsky, Andrei V Bakin

Oncotarget· May 2017

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Nrf2 amplifies oxidative stress via induction of Klf9.
Shoshanna N Zucker, Emily E Fink, Archis Bagati, Sudha Mannava, Anna Bianchi-Smiraglia, Andrei V Bakin

Mol Cell· March 2014

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A bioinspired route to indanes and cyclopentannulated hetarenes via (3+2)-cyclodimerization of donor-acceptor cyclopropanes.
Olga A Ivanova, Ekaterina M Budynina, Dmitriy A Skvortsov, Michelle Limoge, Andrei V Bakin

Chem Commun (Camb)· December 2013

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Integrin-β5 and zyxin mediate formation of ventral stress fibers in response to transforming growth factor β.
Anna Bianchi-Smiraglia, Dimiter Kunnev, Michelle Limoge, Amy Lee, Mary C Beckerle, Andrei V Bakin

Cell Cycle· November 2013

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Androgen-responsive serum response factor target genes regulate prostate cancer cell migration.
Alissa R Verone, Kelly Duncan, Alejandro Godoy, Neelu Yadav, Andrei Bakin

Carcinogenesis· August 2013

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TGF-β autocrine pathway and MAPK signaling promote cell invasiveness and in vivo mammary adenocarcinoma tumor progression.
María Cecilia Daroqui, Paula Vazquez, Elisa Bal de Kier Joffé, Andrei V Bakin, Lydia I Puricelli

Oncol Rep· August 2012

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JunB contributes to Id2 repression and the epithelial-mesenchymal transition in response to transforming growth factor-β.
Megan Gervasi, Anna Bianchi-Smiraglia, Michael Cummings, Qiao Zheng, Dan Wang, Andrei V Bakin

J Cell Biol· March 2012

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Cellular model of Warburg effect identifies tumor promoting function of UCP2 in breast cancer and its suppression by genipin.
Vanniarajan Ayyasamy, Kjerstin M Owens, Mohamed Mokhtar Desouki, Ping Liang, Andrei Bakin

PLoS One· February 2012

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TAK1-TAB2 signaling contributes to bone destruction by breast carcinoma cells.
Alfiya Safina, Paula Sotomayor, Michelle Limoge, Carl Morrison, Andrei V Bakin

Mol Cancer Res· August 2011

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