Publications by authors named "Andrew A Mercer"

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The parapoxvirus Orf virus inhibits dsDNA-mediated type I IFN expression via STING-dependent and STING-independent signalling pathways.
Basheer A AlDaif, Andrew A Mercer, Stephen B Fleming

J Gen Virol· October 2023

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The parapoxvirus Orf virus inhibits IFN-β expression induced by dsRNA.
Basheer A AlDaif, Andrew A Mercer, Stephen B Fleming

Virus Res· January 2022

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The parapoxvirus Orf virus gene encodes an antagonist of the interferon response.
Basheer A AlDaif, Andrew A Mercer, Stephen B Fleming

J Gen Virol· December 2021

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Rescue of a Vaccinia Virus Mutant Lacking IFN Resistance Genes K1L and C7L by the Orf Virus.
Sherief Riad, Yan Xiang, Basheer AlDaif, Andrew A Mercer, Stephen B Fleming

Front Microbiol· July 2020

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Orf Virus IL-10 and VEGF-E Act Synergistically to Enhance Healing of Cutaneous Wounds in Mice.
Lyn M Wise, Gabriella S Stuart, Nicola C Jones, Stephen B Fleming, Andrew A Mercer

J Clin Med· April 2020

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Chemokine-Binding Proteins Encoded by Parapoxvirus of Red Deer of New Zealand Display Evidence of Gene Duplication and Divergence of Ligand Specificity.
Saeed Sharif, Norihito Ueda, Yoshio Nakatani, Lyn M Wise, Sheree Clifton, Andrew A Mercer

Front Microbiol· June 2019

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VEGF Receptor-2 Activation Mediated by VEGF-E Limits Scar Tissue Formation Following Cutaneous Injury.
Lyn M Wise, Gabriella S Stuart, Nicola C Real, Stephen B Fleming, Andrew A Mercer

Adv Wound Care (New Rochelle)· August 2018

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Treatment of limb wounds of horses with orf virus IL-10 and VEGF-E accelerates resolution of exuberant granulation tissue, but does not prevent its development.
Lyn M Wise, Christa J Bodaan, Gabriella S Stuart, Nicola C Real, Zabeen Lateef, Andrew A Mercer

PLoS One· July 2018

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A Broad-Spectrum Chemokine-Binding Protein of Bovine Papular Stomatitis Virus Inhibits Neutrophil and Monocyte Infiltration in Inflammatory and Wound Models of Mouse Skin.
Saeed Sharif, Yoshio Nakatani, Lyn Wise, Michael Corbett, Nicola C Real, Andrew A Mercer

PLoS One· July 2017

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Ankyrin Repeat Proteins of Orf Virus Influence the Cellular Hypoxia Response Pathway.
Da-Yuan Chen, Jacqueline-Alba Fabrizio, Sarah E Wilkins, Keyur A Dave, Jeffrey J Gorman, Andrew A Mercer

J Virol· January 2017

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Deletion of the Chemokine Binding Protein Gene from the Parapoxvirus Orf Virus Reduces Virulence and Pathogenesis in Sheep.
Stephen B Fleming, Catherine McCaughan, Zabeen Lateef, Amy Dunn, Lyn M Wise, Andrew A Mercer

Front Microbiol· January 2017

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Short-term treatment of equine wounds with orf virus IL-10 and VEGF-E dampens inflammation and promotes repair processes without accelerating closure.
Christa J Bodaan, Lyn M Wise, Kirsty A Wakelin, Gabriella S Stuart, Nicola C Real, Andrew A Mercer

Wound Repair Regen· November 2016

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Orf virus interleukin-10 and vascular endothelial growth factor-E modulate gene expression in cultured equine dermal fibroblasts.
Lyn M Wise, Christa J Bodaan, Andrew A Mercer, Christopher B Riley, Christine L Theoret

Vet Dermatol· October 2016

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Orf virus IL-10 reduces monocyte, dendritic cell and mast cell recruitment to inflamed skin.
Jared R Bennett, Zabeen Lateef, Stephen B Fleming, Andrew A Mercer, Lyn M Wise

Virus Res· February 2016

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Orf virus inhibits interferon stimulated gene expression and modulates the JAK/STAT signalling pathway.
Ryan Harvey, Catherine McCaughan, Lyn M Wise, Andrew A Mercer, Stephen B Fleming

Virus Res· October 2015

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Structures of Orf Virus Chemokine Binding Protein in Complex with Host Chemokines Reveal Clues to Broad Binding Specificity.
Rafael M Couñago, Karen M Knapp, Yoshio Nakatani, Stephen B Fleming, Michael Corbett, Andrew A Mercer

Structure· July 2015

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Molecular genetic analysis of orf virus: a poxvirus that has adapted to skin.
Stephen B Fleming, Lyn M Wise, Andrew A Mercer

Viruses· March 2015

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Orf virus IL-10 accelerates wound healing while limiting inflammation and scarring.
Lyn M Wise, Gabriella S Stuart, Nicola C Real, Stephen B Fleming, Andrew A Mercer

Wound Repair Regen· February 2015

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Effect of a broad-specificity chemokine-binding protein on brain leukocyte infiltration and infarct development.
Seyoung Lee, Hannah X Chu, Hyun Ah Kim, Nicola C Real, Saeed Sharif, Andrew A Mercer

Stroke· February 2015

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Poxviral ankyrin proteins.
Michael H Herbert, Christopher J Squire, Andrew A Mercer

Viruses· February 2015

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Inactivated ORF virus shows antifibrotic activity and inhibits human hepatitis B virus (HBV) and hepatitis C virus (HCV) replication in preclinical models.
Daniela Paulsen, Andreas Urban, Andreas Knorr, Claudia Hirth-Dietrich, Angela Siegling, Andrew A Mercer

PLoS One· May 2014

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The vascular endothelial growth factor (VEGF)-E encoded by orf virus regulates keratinocyte proliferation and migration and promotes epidermal regeneration.
Lyn M Wise, Marie K Inder, Nicola C Real, Gabriella S Stuart, Stephen B Fleming, Andrew A Mercer

Cell Microbiol· September 2012

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How viruses affect the cell cycle through manipulation of the APC/C.
Min Mo, Saleha Shahar, Stephen B Fleming, Andrew A Mercer

Trends Microbiol· September 2012

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ORFV: a novel oncolytic and immune stimulating parapoxvirus therapeutic.
Julia L Rintoul, Chantal G Lemay, Lee-Hwa Tai, Marianne M Stanford, Theresa J Falls, Andrew A Mercer

Mol Ther· June 2012

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Development of orf virus as a bifunctional recombinant vaccine: surface display of Echinococcus granulosus antigen EG95 by fusion to membrane structural proteins.
Joanne L Tan, Norihito Ueda, David Heath, Andrew A Mercer, Stephen B Fleming

Vaccine· January 2012

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