Publications by authors named "Andrew Ayscough"

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Discovery of : A Highly Potent, Selective, and CNS Penetrant mGluR Allosteric Agonist.
Louise Dickson, Martin Teall, Elodie Chevalier, Toni Cheung, Gemma M Liwicki, Andrew P Ayscough

ACS Med Chem Lett· April 2023

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Assessing molecular scaffolds for CNS drug discovery.
Joan Mayol-Llinàs, Adam Nelson, William Farnaby, Andrew Ayscough

Drug Discov Today· July 2017

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1,2,4-Triazolo-[1,5-a]pyridine HIF Prolylhydroxylase Domain-1 (PHD-1) Inhibitors With a Novel Monodentate Binding Interaction.
Saleh Ahmed, Andrew Ayscough, Greg R Barker, Hannah E Canning, Richard Davenport

J Med Chem· July 2017

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Peptidomimetic inhibitors of bacterial peptide deformylase.
Stephen P East, Andrew Ayscough, Ian Toogood-Johnson, Steven Taylor, Wayne Thomas

Bioorg Med Chem Lett· July 2011

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CHR-2797: an antiproliferative aminopeptidase inhibitor that leads to amino acid deprivation in human leukemic cells.
David Krige, Lindsey A Needham, Lindsay J Bawden, Nicolas Flores, Hannah Farmer, Andrew Ayscough

Cancer Res· August 2008

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Synthesis of a simplified analogue of eleutherobin via a Claisen rearrangement and ring closing metathesis strategy.
Gary C H Chiang, Andrew D Bond, Andrew Ayscough, Gilles Pain, Sylvie Ducki

Chem Commun (Camb)· April 2005

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Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the methylene spacer and the P1' side chain.
Stephen J Davies, Andrew P Ayscough, R Paul Beckett, Ryan A Bragg, John M Clements

Bioorg Med Chem Lett· August 2003

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Structure--activity relationships of the peptide deformylase inhibitor BB-3497: modification of the P2' and P3' side chains.
Stephen J Davies, Andrew P Ayscough, R Paul Beckett, John M Clements, Sheila Doel

Bioorg Med Chem Lett· August 2003

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