Publications by authors named "Andrew C Chan"

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Publisher Correction: Fifty years of monoclonals: the past, present and future of antibody therapeutics.
Andrew C Chan, Greg D Martyn, Paul J Carter

Nat Rev Immunol· December 2025

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Fifty years of monoclonals: the past, present and future of antibody therapeutics.
Andrew C Chan, Greg D Martyn, Paul J Carter

Nat Rev Immunol· October 2025

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Sequence diversity lost in early pregnancy.
Gudny A Arnadottir, Hakon Jonsson, Tanja Schlaikjær Hartwig, Jennifer R Gruhn, Peter Loof Møller, Andrew Chi-Ho Chan

Nature· June 2025

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Maternal PRDM10 activates essential genes for oocyte-to-embryo transition.
Michelle K Y Seah, Brenda Y Han, Yan Huang, Louise J H Rasmussen, Andrina J Stäubli, Andrew Chi-Ho Chan

Nat Commun· February 2025

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Improving Health Equity in Rheumatology Through Workforce Diversification and Support for Health Equity Research and Education.
Maria T Vassileva, Vandana Suresh, Andrew C Chan, Alisha Valdez Akinsete, Irene Blanco

Arthritis Rheumatol· July 2024

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Vaccination and protective immunity to SARS-CoV-2 omicron variants in people with immunodeficiencies.
Angalee Nadesalingam, Diego Cantoni, Ernest T Aguinam, Andrew Cy Chan, Minna Paloniemi

Lancet Microbe· February 2023

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NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22.
Marianne R Spalinger, Stephanie Kasper, Claudia Gottier, Silvia Lang, Kirstin Atrott, Andrew C Chan

J Clin Invest· February 2023

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B cell-mediated regulatory mechanisms control tumor-promoting intestinal inflammation.
Christian Melcher, Jinbo Yu, Vu Huy Hoang Duong, Katrin Westphal, Noushin Helmi Siasi Farimany, Andrew C Chan

Cell Rep· July 2022

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Identification of a unique epigenetic profile in women with diminished ovarian reserve.
Kristina W Olsen, Juan Castillo-Fernandez, Andrew Cho Chan, Nina la Cour Freiesleben, Anne Zedeler

Fertil Steril· March 2021

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Autoimmunity linked protein phosphatase PTPN22 as a target for cancer immunotherapy.
Rafael Cubas, Zia Khan, Qian Gong, Marina Moskalenko, Huizhong Xiong, Andrew C Chan

J Immunother Cancer· October 2020

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30 Years of Biotherapeutics Development-What Have We Learned?
Nico Ghilardi, Rajita Pappu, Joseph R Arron, Andrew C Chan

Annu Rev Immunol· April 2020

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Chromosome errors in human eggs shape natural fertility over reproductive life span.
Jennifer R Gruhn, Agata P Zielinska, Vallari Shukla, Robert Blanshard, Antonio Capalbo, Andrew Chi-Ho Chan

Science· September 2019

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Protein tyrosine phosphatase non-receptor type 22 modulates colitis in a microbiota-dependent manner.
Marianne R Spalinger, Thomas Sb Schmidt, Marlene Schwarzfischer, Larissa Hering, Kirstin Atrott, Andrew C Chan

J Clin Invest· May 2019

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Surface receptor Toso controls B cell-mediated regulation of T cell immunity.
Jinbo Yu, Vu Huy Hoang Duong, Katrin Westphal, Andreas Westphal, Abdulhadi Suwandi, Andrew C Chan

J Clin Invest· May 2018

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Ocrelizumab: A New Therapeutic Paradigm for Multiple Sclerosis.
Peter Chin, Andrew C Chan

Biochemistry· February 2018

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PTPN22 regulates NLRP3-mediated IL1B secretion in an autophagy-dependent manner.
Marianne R Spalinger, Silvia Lang, Claudia Gottier, Xuezhi Dai, David J Rawlings, Andrew C Chan

Autophagy· September 2017

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NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22.
Marianne R Spalinger, Stephanie Kasper, Claudia Gottier, Silvia Lang, Kirstin Atrott, Andrew C Chan

J Clin Invest· November 2016

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NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22.
Marianne R Spalinger, Stephanie Kasper, Claudia Gottier, Silvia Lang, Kirstin Atrott, Andrew C Chan

J Clin Invest· May 2016

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Recurrent viral infections associated with a homozygous CORO1A mutation that disrupts oligomerization and cytoskeletal association.
Christina S Yee, Michel J Massaad, Wayne Bainter, Toshiro K Ohsumi, Niko Föger, Andrew C Chan

J Allergy Clin Immunol· March 2016

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Regulation of T Cell Receptor Signaling by DENND1B in TH2 Cells and Allergic Disease.
Chiao-Wen Yang, Caroline D Hojer, Meijuan Zhou, Xiumin Wu, Arthur Wuster, Andrew C Chan

Cell· January 2016

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Stratified medicine in inflammatory disorders: From theory to practice.
Joseph R Arron, Michael J Townsend, Mary E Keir, Brian L Yaspan, Andrew C Chan

Clin Immunol· November 2015

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Autoimmunity-associated protein tyrosine phosphatase PEP negatively regulates IFN-α receptor signaling.
Derek A Holmes, Eric Suto, Wyne P Lee, Qinglin Ou, Qian Gong, Andrew C Chan

J Exp Med· June 2015

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Dusp5 negatively regulates IL-33-mediated eosinophil survival and function.
Derek A Holmes, Jung-Hua Yeh, Donghong Yan, Min Xu, Andrew C Chan

EMBO J· January 2015

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Pillars article: Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science. 1994. 263: 1136-1139.
Makio Iwashima, Bryan A Irving, Nicolai S C van Oers, Andrew C Chan, Arthur Weiss

J Immunol· November 2014

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Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity.
Catalina Lee-Chang, Monica Bodogai, Kanako Moritoh, Purevdorj B Olkhanud, Andrew C Chan

Blood· August 2014

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