Publications by authors named "Andrew Castle"

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Single extracellular vesicle detection assay identifies membrane-associated α-synuclein as an early-stage biomarker in Parkinson's disease.
Shijun Yan, Wenjing Zhang, Xinying Li, Suman Dutta, Andrew R Castle

Cell Rep Med· March 2025

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Prion Protein Endoproteolysis: Cleavage Sites, Mechanisms and Connections to Prion Disease.
Andrew R Castle, David Westaway

J Neurochem· January 2025

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Monitoring α-synuclein ubiquitination dynamics reveals key endosomal effectors mediating its trafficking and degradation.
Dmitry Zenko, Jade Marsh, Andrew R Castle, Rahel Lewin, Roman Fischer

Sci Adv· June 2023

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Beta-endoproteolysis of the cellular prion protein by dipeptidyl peptidase-4 and fibroblast activation protein.
Andrew R Castle, Sang-Gyun Kang, Ghazaleh Eskandari-Sedighi, Serene Wohlgemuth, My-Anh Nguyen

Proc Natl Acad Sci U S A· January 2023

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Investigating CRISPR/Cas9 gene drive for production of disease-preventing prion gene alleles.
Andrew R Castle, Serene Wohlgemuth, Luis Arce, David Westaway

PLoS One· June 2022

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Prion protein with a mutant N-terminal octarepeat region undergoes cobalamin-dependent assembly into high-molecular weight complexes.
Nathalie Daude, Agnes Lau, Ilaria Vanni, Sang-Gyun Kang, Andrew R Castle

J Biol Chem· April 2022

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Susceptibility of Beavers to Chronic Wasting Disease.
Allen Herbst, Serene Wohlgemuth, Jing Yang, Andrew R Castle, Diana Martinez Moreno

Biology (Basel)· April 2022

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Application of high-throughput, capillary-based Western analysis to modulated cleavage of the cellular prion protein.
Andrew R Castle, Nathalie Daude, Sabine Gilch, David Westaway

J Biol Chem· February 2019

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The cellular and pathologic prion protein.
Andrew C Gill, Andrew R Castle

Handb Clin Neurol· September 2018

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Physiological Functions of the Cellular Prion Protein.
Andrew R Castle, Andrew C Gill

Front Mol Biosci· April 2017

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Use of sustainable chemistry to produce an acyl amino acid surfactant.
Gabriel O Reznik, Prashanth Vishwanath, Michelle A Pynn, Joy M Sitnik, Jeffrey J Todd, Andrew B Castle

Appl Microbiol Biotechnol· May 2010

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Lean thinking on the wards.
Andrew Castle

Nurs Stand· August 2008

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Service improvement. In the driving seat.
Andrew Castle, Rachel Harvey, Andie Hallihan

Health Serv J· February 2007

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