Publications by authors named "Andrew D Rouillard"

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Systems Analysis Implicates WAVE2 Complex in the Pathogenesis of Developmental Left-Sided Obstructive Heart Defects.
Jonathan J Edwards, Andrew D Rouillard, Nicolas F Fernandez, Zichen Wang, Alexander Lachmann

JACC Basic Transl Sci· April 2020

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Could advances in representation learning in Artificial Intelligence provide the new paradigm for data integration in drug discovery?
Vinaya Vijayan, Andrew D Rouillard, Deepak K Rajpal, Pankaj Agarwal

Expert Opin Drug Discov· March 2019

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Systematic interrogation of diverse Omic data reveals interpretable, robust, and generalizable transcriptomic features of clinically successful therapeutic targets.
Andrew D Rouillard, Mark R Hurle, Pankaj Agarwal

PLoS Comput Biol· May 2018

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The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins.
Andrew D Rouillard, Gregory W Gundersen, Nicolas F Fernandez, Zichen Wang, Caroline D Monteiro

Database (Oxford)· November 2017

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Pharos: Collating protein information to shed light on the druggable genome.
Dac-Trung Nguyen, Stephen Mathias, Cristian Bologa, Soren Brunak, Nicolas Fernandez, Andrew D Rouillard

Nucleic Acids Res· January 2017

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Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd.
Zichen Wang, Caroline D Monteiro, Kathleen M Jagodnik, Nicolas F Fernandez, Gregory W Gundersen, Andrew D Rouillard

Nat Commun· September 2016

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L1000CDS: LINCS L1000 characteristic direction signatures search engine.
Qiaonan Duan, St Patrick Reid, Neil R Clark, Zichen Wang, Nicolas F Fernandez, Andrew D Rouillard

NPJ Syst Biol Appl· August 2016

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Enrichr: a comprehensive gene set enrichment analysis web server 2016 update.
Maxim V Kuleshov, Matthew R Jones, Andrew D Rouillard, Nicolas F Fernandez, Qiaonan Duan

Nucleic Acids Res· July 2016

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Reprint of "Abstraction for data integration: Fusing mammalian molecular, cellular and phenotype big datasets for better knowledge extraction".
Andrew D Rouillard, Zichen Wang, Avi Ma'ayan

Comput Biol Chem· December 2015

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Publisher’s Note:Abstraction for data integration:Fusing mammalian molecular, cellular and phenotype big datasets for better knowledge extraction.
Andrew D Rouillard, Zichen Wang, Avi Ma'ayan

Comput Biol Chem· October 2015

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GEO2Enrichr: browser extension and server app to extract gene sets from GEO and analyze them for biological functions.
Gregory W Gundersen, Matthew R Jones, Andrew D Rouillard, Yan Kou, Caroline D Monteiro

Bioinformatics· September 2015

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Drug/Cell-line Browser: interactive canvas visualization of cancer drug/cell-line viability assay datasets.
Qiaonan Duan, Zichen Wang, Nicolas F Fernandez, Andrew D Rouillard, Christopher M Tan

Bioinformatics· November 2014

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Lean Big Data integration in systems biology and systems pharmacology.
Avi Ma'ayan, Andrew D Rouillard, Neil R Clark, Zichen Wang, Qiaonan Duan

Trends Pharmacol Sci· September 2014

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Coupled agent-based and finite-element models for predicting scar structure following myocardial infarction.
Andrew D Rouillard, Jeffrey W Holmes

Prog Biophys Mol Biol· August 2014

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LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures.
Qiaonan Duan, Corey Flynn, Mario Niepel, Marc Hafner, Jeremy L Muhlich, Andrew D Rouillard

Nucleic Acids Res· July 2014

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Mechanical boundary conditions bias fibroblast invasion in a collagen-fibrin wound model.
Andrew D Rouillard, Jeffrey W Holmes

Biophys J· February 2014

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Mechanical regulation of fibroblast migration and collagen remodelling in healing myocardial infarcts.
Andrew D Rouillard, Jeffrey W Holmes

J Physiol· September 2012

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Regional mechanics determine collagen fiber structure in healing myocardial infarcts.
Gregory M Fomovsky, Andrew D Rouillard, Jeffrey W Holmes

J Mol Cell Cardiol· May 2012

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Methods for photocrosslinking alginate hydrogel scaffolds with high cell viability.
Andrew D Rouillard, Caroline M Berglund, Jae Youn Lee, William J Polacheck, Yvonne Tsui

Tissue Eng Part C Methods· February 2011

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Control of the electromechanical properties of alginate hydrogels via ionic and covalent cross-linking and microparticle doping.
Andrew D Rouillard, Yvonne Tsui, William J Polacheck, Jae Youn Lee, Lawrence J Bonassar

Biomacromolecules· August 2010

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