Publications by authors named "Andrew Dippel"

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Accelerating high-concentration monoclonal antibody development with large-scale viscosity data and ensemble deep learning.
Lateefat A Kalejaye, Jia-Min Chu, I-En Wu, Bismark Amofah, Amber Lee, Andrew Dippel

MAbs· December 2025

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Preemptive optimization of a clinical antibody for broad neutralization of SARS-CoV-2 variants and robustness against viral escape.
Fangqiang Zhu, Saravanan Rajan, Conor F Hayes, Ka Yin Kwong, Andre R Goncalves, Andrew Dippel

Sci Adv· March 2025

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IL-2-armored peptide-major histocompatibility class I bispecific antibodies redirect antiviral effector memory CD8+ T cells to induce potent anti-cancer cytotoxic activity with limited cytokine release.
John S Schardt, Even Walseng, Kim Le, Chunning Yang, Pooja Shah, Andrew Dippel

MAbs· August 2024

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Toward enhancement of antibody thermostability and affinity by computational design in the absence of antigen.
Mark Hutchinson, Jeffrey A Ruffolo, Nantaporn Haskins, Michael Iannotti, Giuliana Vozza, Andrew Dippel

MAbs· June 2024

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AZD3152 neutralizes SARS-CoV-2 historical and contemporary variants and is protective in hamsters and well tolerated in adults.
Yingyun Cai, Seme Diallo, Kim Rosenthal, Kuishu Ren, Daniel J Flores, Andrew Dippel

Sci Transl Med· June 2024

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Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the C1-C interface.
John D Bagert, Vaheh Oganesyan, Chi-I Chiang, Mike Iannotti, Jia Lin, Andrew Dippel

MAbs· November 2023

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A scalable and high yielding SARS-CoV-2 spike protein receptor binding domain production process.
Valeria Riguero, Jared Delmar, Andrew Dippel, Patrick McTamney, Ethan Luo

Protein Expr Purif· May 2023

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Developability profiling of a panel of Fc engineered SARS-CoV-2 neutralizing antibodies.
Andrew Dippel, Austin Gallegos, Vineela Aleti, Arnita Barnes, Xiaoru Chen

MAbs· December 2022

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Chemiluminescent sensors for quantitation of the bacterial second messenger cyclic di-GMP.
Wyatt A Anderson, Andrew B Dippel, Michael M Maiden, Christopher M Waters, Ming C Hammond

Methods Enzymol· June 2021

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Tuning the Innate Immune Response to Cyclic Dinucleotides by Using Atomic Mutagenesis.
Yao Li, Andrea Fin, Alexander R Rovira, Yichi Su, Andrew B Dippel

Chembiochem· September 2020

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Development of Ratiometric Bioluminescent Sensors for Detection of Bacterial Signaling.
Andrew B Dippel, Wyatt A Anderson, Jin Hwan Park, Fitnat H Yildiz, Ming C Hammond

ACS Chem Biol· April 2020

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A Poxin on Both of Your Houses: Poxviruses Degrade the Immune Signal cGAMP.
Andrew B Dippel, Ming C Hammond

Biochemistry· May 2019

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Chemiluminescent Biosensors for Detection of Second Messenger Cyclic di-GMP.
Andrew B Dippel, Wyatt A Anderson, Robert S Evans, Samuel Deutsch, Ming C Hammond

ACS Chem Biol· July 2018

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In Vivo Biochemistry: Single-Cell Dynamics of Cyclic Di-GMP in Escherichia coli in Response to Zinc Overload.
Jongchan Yeo, Andrew B Dippel, Xin C Wang, Ming C Hammond

Biochemistry· January 2018

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Probing the effectiveness of spectroscopic reporter unnatural amino acids: a structural study.
Andrew B Dippel, Gregory M Olenginski, Nicole Maurici, Melanie T Liskov, Scott H Brewer

Acta Crystallogr D Struct Biol· January 2016

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