Publications by authors named "Andrew Geall"

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Divergent Delivery and Expression Kinetics of Lipid and Polymeric Nanoparticles across mRNA Modalities.
Irafasha C Casmil, Josh J Friesen, Nuthan V Bathula, Anneke Strumpel, Chia Hao Ho, Andrew J Geall

Adv Sci (Weinh)· October 2025

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Durability of next-generation self-replicating RNA vaccine RBI-4000: a phase 1, randomized open label clinical trial.
Christian J Maine, Gaelle Picarda, Shigeki J Miyake-Stoner, Brandon Essink, Guillermo Somodevilla, Andrew J Geall

Commun Med (Lond)· September 2025

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Safety and immunogenicity of an optimized self-replicating RNA platform for low dose or single dose vaccine applications: a randomized, open label Phase I study in healthy volunteers.
Christian J Maine, Shigeki J Miyake-Stoner, Darina S Spasova, Gaelle Picarda, Annie C Chou, Andrew J Geall

Nat Commun· January 2025

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Targeted tissue delivery of RNA therapeutics using antibody-oligonucleotide conjugates (AOCs).
Barbora Malecova, Rob S Burke, Michael Cochran, Michael D Hood, Rachel Johns, Andrew Geall

Nucleic Acids Res· July 2023

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Next generation self-replicating RNA vectors for vaccines and immunotherapies.
Parinaz Aliahmad, Shigeki J Miyake-Stoner, Andrew J Geall, Nathaniel S Wang

Cancer Gene Ther· June 2023

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Vaccines on demand, part II: future reality.
Andrew J Geall, Zoltan Kis, Jeffrey B Ulmer

Expert Opin Drug Discov· February 2023

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OX40 agonist stimulation increases and sustains humoral and cell-mediated responses to SARS-CoV-2 protein and saRNA vaccines.
Rebekka Duhen, Michael Beymer, Shawn M Jensen, Srinivas Abbina, Suraj Abraham, Andrew J Geall

Front Immunol· October 2022

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Polymeric and lipid nanoparticles for delivery of self-amplifying RNA vaccines.
Anna K Blakney, Paul F McKay, Kai Hu, Karnyart Samnuan, Nikita Jain, Andrew Geall

J Control Release· October 2021

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An Update on Self-Amplifying mRNA Vaccine Development.
Anna K Blakney, Shell Ip, Andrew J Geall

Vaccines (Basel)· January 2021

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Self-Amplifying RNA Vaccines for Venezuelan Equine Encephalitis Virus Induce Robust Protective Immunogenicity in Mice.
Marcelo M Samsa, Lesley C Dupuy, Clayton W Beard, Carolyn M Six, Connie S Schmaljohn, Andrew J Geall

Mol Ther· April 2019

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Neutralization of the Plasmodium-encoded MIF ortholog confers protective immunity against malaria infection.
Alvaro Baeza Garcia, Edwin Siu, Tiffany Sun, Valerie Exler, Luis Brito, Andrew Geall

Nat Commun· July 2018

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Self-Amplifying mRNA Vaccines Expressing Multiple Conserved Influenza Antigens Confer Protection against Homologous and Heterosubtypic Viral Challenge.
Diletta Magini, Cinzia Giovani, Simona Mangiavacchi, Silvia Maccari, Raffaella Cecchi, Andrew J Geall

PLoS One· July 2017

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Induction of an IFN-Mediated Antiviral Response by a Self-Amplifying RNA Vaccine: Implications for Vaccine Design.
Timothy Pepini, Anne-Marie Pulichino, Thomas Carsillo, Alicia L Carlson, Farid Sari-Sarraf, Andrew J Geall

J Immunol· May 2017

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Immunogenicity and protective efficacy induced by self-amplifying mRNA vaccines encoding bacterial antigens.
Giulietta Maruggi, Emiliano Chiarot, Cinzia Giovani, Scilla Buccato, Stefano Bonacci, Andrew Geall

Vaccine· January 2017

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RNA Vaccination Therapy: Advances in an Emerging Field.
Sebastian Kreiter, Mustafa Diken, Steve Pascolo, Smita K Nair, Kris M Thielemans, Andrew Geall

J Immunol Res· November 2016

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Recent innovations in mRNA vaccines.
Jeffrey B Ulmer, Andrew J Geall

Curr Opin Immunol· August 2016

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Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin.
Michela Brazzoli, Diletta Magini, Alessandra Bonci, Scilla Buccato, Cinzia Giovani, Andrew J Geall

J Virol· January 2016

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CD8 T-cell priming upon mRNA vaccination is restricted to bone-marrow-derived antigen-presenting cells and may involve antigen transfer from myocytes.
Sandra Lazzaro, Cinzia Giovani, Simona Mangiavacchi, Diletta Magini, Domenico Maione, Andrew J Geall

Immunology· October 2015

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Self-amplifying mRNA vaccines.
Luis A Brito, Sushma Kommareddy, Domenico Maione, Yasushi Uematsu, Cinzia Giovani, Andrew J Geall

Adv Genet· September 2015

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Control of alphavirus-based gene expression using engineered riboswitches.
Christie L Bell, Dong Yu, Christina D Smolke, Andrew J Geall, Clayton W Beard

Virology· September 2015

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Potent immune responses in rhesus macaques induced by nonviral delivery of a self-amplifying RNA vaccine expressing HIV type 1 envelope with a cationic nanoemulsion.
Willy M Bogers, Herman Oostermeijer, Petra Mooij, Gerrit Koopman, Ernst J Verschoor, Andrew J Geall

J Infect Dis· March 2015

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Introduction to RNA-based vaccines and therapeutics.
Andrew J Geall, Jeffrey B Ulmer

Expert Rev Vaccines· February 2015

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Vaccines 'on demand': science fiction or a future reality.
Jeffrey B Ulmer, Monique K Mansoura, Andrew J Geall

Expert Opin Drug Discov· February 2015

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A cationic nanoemulsion for the delivery of next-generation RNA vaccines.
Luis A Brito, Michelle Chan, Christine A Shaw, Armin Hekele, Thomas Carsillo, Andrew J Geall

Mol Ther· December 2014

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Nucleic acid vaccines: prospects for non-viral delivery of mRNA vaccines.
Raquel P Deering, Sushma Kommareddy, Jeffrey B Ulmer, Luis A Brito, Andrew J Geall

Expert Opin Drug Deliv· June 2014

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