Publications by authors named "Andrew Germain"

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Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects.
Florence F Wagner, Joshua A Bishop, Jennifer P Gale, Xi Shi, Michelle Walk, Andrew R Germain

ACS Chem Biol· July 2016

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Discovery of bisamide-heterocycles as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake.
Chris Dockendorff, Patrick W Faloon, Andrew Germain, Miao Yu, Willmen Youngsaye

Bioorg Med Chem Lett· June 2015

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Diversity-oriented synthesis yields a new drug lead for treatment of chagas disease.
Sivaraman Dandapani, Andrew R Germain, Ivan Jewett, Sebastian le Quement, Jean-Charles Marie

ACS Med Chem Lett· February 2014

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Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Andrew R Germain, Leigh C Carmody, Partha P Nag, Barbara Morgan, Lynn Verplank

Bioorg Med Chem Lett· March 2013

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Phenotypic high-throughput screening elucidates target pathway in breast cancer stem cell-like cells.
Leigh C Carmody, Andrew R Germain, Lynn VerPlank, Partha P Nag, Benito Muñoz

J Biomol Screen· October 2012

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Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies.
Chris Dockendorff, Marek M Nagiec, Michel Weïwer, Sara Buhrlage, Amal Ting, Andrew Germain

ACS Med Chem Lett· October 2012

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Identification of a selective small molecule inhibitor of breast cancer stem cells.
Andrew R Germain, Leigh C Carmody, Barbara Morgan, Cristina Fernandez, Erin Forbeck

Bioorg Med Chem Lett· May 2012

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Identification of small-molecule inhibitors of Trypansoma cruzi replication.
Andrew R Germain, Leigh C Carmody, Chris Dockendorff, Cristina Galan-Rodriguez, Ana Rodriguez

Bioorg Med Chem Lett· December 2011

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Synthesis of the azaphilones (+)-sclerotiorin and (+)-8-O-methylsclerotiorinamine utilizing (+)-sparteine surrogates in copper-mediated oxidative dearomatization.
Andrew R Germain, Daniel M Bruggemeyer, Jianglong Zhu, Cedric Genet, Peter O'Brien

J Org Chem· April 2011

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Synthesis of azaphilones and related molecules by employing cycloisomerization of o-alkynylbenzaldehydes.
Jianglong Zhu, Andrew R Germain, John A Porco

Angew Chem Int Ed Engl· February 2004

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