Publications by authors named "Andrew Getahun"

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Deletion of Ptpn2 in B cells promotes autoimmunity via TLR and JAK/STAT signaling.
Bridget N Alexander, Soojin Kim, Kristen L Wells, Maya J Hunter, Kevin P Toole, Andrew Getahun

JCI Insight· December 2025

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Allergens abrogate antiinflammatory DNA effects and unmask macrophage-driven neutrophilic asthma via ILC2/STING/TNF-α signaling.
Anand Sripada, Divya Verma, Rangati Varma, Kapil Sirohi, Carolyn Kwiat, Andrew Getahun

J Clin Invest· August 2025

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Interleukin-1 signaling and CD4 T cells control B cell recruitment to the lungs in chronic beryllium disease.
Joseph M Gaballa, Caley Valdez, Douglas G Mack, Faiz Minhajuddin, Masoom Raza, Andrew Getahun

Front Immunol· May 2025

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The Src-family kinase Lyn plays a critical role in establishing and maintaining B cell anergy by suppressing PI3K-dependent signaling.
Brigita E Fiske, Scott M Wemlinger, Bergren W Crute, Andrew Getahun

bioRxiv· May 2024

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Failed Downregulation of PI3K Signaling Makes Autoreactive B Cells Receptive to Bystander T Cell Help.
Brigita E Fiske, Andrew Getahun

J Immunol· April 2024

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Polymorphic KIR3DL3 expression modulates tissue-resident and innate-like T cells.
William H Palmer, Laura Ann Leaton, Ana Campos Codo, Bergren Crute, James Roest, Andrew Getahun

Sci Immunol· June 2023

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Failed down-regulation of PI3K signaling makes autoreactive B cells receptive to bystander T cell help.
Brigita E Fiske, Andrew Getahun

bioRxiv· January 2023

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Comparative analysis of the repertoire of insulin-reactive B cells in type 1 diabetes-prone and resistant mice.
Maureen Banach, Isaac T W Harley, Andrew Getahun, John C Cambier

Front Immunol· October 2022

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Role of inhibitory signaling in peripheral B cell tolerance.
Andrew Getahun

Immunol Rev· May 2022

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Preclinical Analysis of Candidate Anti-Human CD79 Therapeutic Antibodies Using a Humanized CD79 Mouse Model.
Scott M Wemlinger, Chelsea R Parker Harp, Bo Yu, Ian R Hardy, Matthew Seefeldt, Andrew Getahun

J Immunol· April 2022

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B cells promote CD8 T cell primary and memory responses to subunit vaccines.
Jared Klarquist, Eric W Cross, Scott B Thompson, Benjamin Willett, Daniel L Aldridge, Andrew Getahun

Cell Rep· August 2021

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Inhibitory Receptor Trap: A Platform for Discovery of Inhibitory Receptors That Utilize Inositol Lipid and Phosphotyrosine Phosphatase Effectors.
Bergren W Crute, Rachel Sheraden, Vanessa L Ott, Isaac T W Harley, Andrew Getahun

Front Immunol· June 2021

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Selective Loss of Responsiveness to Exogenous but Not Endogenous Cyclic-Dinucleotides in Mice Expressing STING-R231H.
Melissa M Walker, Soojin Kim, William J Crisler, Kimberlie Nguyen, Laurel L Lenz, Andrew Getahun

Front Immunol· March 2021

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γδ T cells shape memory-phenotype αβ T cell populations in non-immunized mice.
Swati Popat Phalke, Yafei Huang, Kira Rubtsova, Andrew Getahun, Deming Sun

PLoS One· February 2020

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The c-Myc/miR17-92/PTEN Axis Tunes PI3K Activity to Control Expression of Recombination Activating Genes in Early B Cell Development.
David Benhamou, Verena Labi, Andrew Getahun, Eli Benchetrit, Reem Dowery

Front Immunol· October 2019

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Non-Antibody-Secreting Functions of B Cells and Their Contribution to Autoimmune Disease.
Andrew Getahun, John C Cambier

Annu Rev Cell Dev Biol· October 2019

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A Precision B Cell-Targeted Therapeutic Approach to Autoimmunity Caused by Phosphatidylinositol 3-Kinase Pathway Dysregulation.
S Elizabeth Franks, Andrew Getahun, John C Cambier

J Immunol· June 2019

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Protective role of B cells in sterile particulate-induced lung injury.
Shaikh M Atif, Douglas G Mack, Amy S McKee, Javier Rangel-Moreno, Allison K Martin, Andrew Getahun

JCI Insight· May 2019

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Elevated PTEN expression maintains anergy in human B cells and reveals unexpectedly high repertoire autoreactivity.
Mia J Smith, B Rhodes Ford, Marynette Rihanek, Brianne M Coleman, Andrew Getahun

JCI Insight· February 2019

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Silencing of high-affinity insulin-reactive B lymphocytes by anergy and impact of the NOD genetic background in mice.
Mia J Smith, Rochelle M Hinman, Andrew Getahun, Soojin Kim, Thomas A Packard

Diabetologia· December 2018

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B Cell-Intrinsic STING Signaling Triggers Cell Activation, Synergizes with B Cell Receptor Signals, and Promotes Antibody Responses.
Melissa M Walker, Bergren W Crute, John C Cambier, Andrew Getahun

J Immunol· November 2018

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High-efficiency RNA-based reprogramming of human primary fibroblasts.
Igor Kogut, Sandra M McCarthy, Maryna Pavlova, David P Astling, Xiaomi Chen, Andrew Getahun

Nat Commun· February 2018

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Impaired B cell function during viral infections due to PTEN-mediated inhibition of the PI3K pathway.
Andrew Getahun, Scott M Wemlinger, Pratyaydipta Rudra, Mario L Santiago, Linda F van Dyk

J Exp Med· April 2017

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Targeting B cells in treatment of autoimmunity.
S Elizabeth Franks, Andrew Getahun, P Mark Hogarth, John C Cambier

Curr Opin Immunol· December 2016

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B Cell Receptor Affinity for Insulin Dictates Autoantigen Acquisition and B Cell Functionality in Autoimmune Diabetes.
Thomas A Packard, Mia J Smith, Francis J Conrad, Sara A Johnson, Andrew Getahun

J Clin Med· November 2016

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